The Role Of Nrf2 Transcription Factor

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The Role Of Nrf2 Transcription Factor

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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-11-27

The Role Of Nrf2 Transcription Factor written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-27 with Science categories.

The regulation of the transcription factor NRF2 opens a therapeutic window for a host of chronic degenerative diseases, such as diabetes and its complications, cancer, obesity, neurodegenerative diseases, kidney diseases, immunological diseases, and so on. The ability to regulate cytoprotective functions such as antioxidant defenses or pro-apoptotic or anti-apoptotic functions is of utmost importance. Currently, there are therapeutic agents to activate or inhibit NRF2; research should focus on understanding how NRF2 makes “the decision” to perform one function or another.

Inflammation And Cancer

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Author : Bharat B. Aggarwal
language : en
Publisher: Springer
Release Date : 2014-05-12

Inflammation And Cancer written by Bharat B. Aggarwal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.

This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Natural Bioactive Compounds

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Author : Rajeshwar P. Sinha
language : en
Publisher: Academic Press
Release Date : 2020-10-06

Natural Bioactive Compounds written by Rajeshwar P. Sinha and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-06 with Science categories.

Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications. - Explores natural sources of bioactive compounds, including cyanobacteria, bacteria, viruses, fungi and higher plants - Discusses the potential applications of biological products, such as their use in medicine (antibiotics, cancer research, immunology), as food additives, supplements and technological substances - Analyzes the contributions of emerging or developing technologies for the study of bioactive natural compounds (characterization and purification)

Targeting Cellular Signalling Pathways In Lung Diseases

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Author : Kamal Dua
language : en
Publisher: Springer Nature
Release Date : 2021-07-02

Targeting Cellular Signalling Pathways In Lung Diseases written by Kamal Dua and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-02 with Medical categories.

The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.

Dietary Interventions In Liver Disease

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Author : Ronald Ross Watson
language : en
Publisher: Academic Press
Release Date : 2019-01-16

Dietary Interventions In Liver Disease written by Ronald Ross Watson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-16 with Science categories.

Dietary Interventions in Liver Disease: Foods, Nutrients, and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the liver. It provides nutritional treatment options for those suffering from liver disease. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus illustrating that variations in intake can change antioxidant and disease preventing non-nutrients that affect liver health and/or disease promotion. This book is a valuable resource for biomedical researchers who focus on identifying the causes of liver diseases and food scientists targeting health-related product development.

Who Global Air Quality Guidelines

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Author : Weltgesundheitsorganisation
language : en
Publisher: World Health Organization
Release Date : 2021-09-07

Who Global Air Quality Guidelines written by Weltgesundheitsorganisation and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-07 with Nature categories.

The main objective of these updated global guidelines is to offer health-based air quality guideline levels, expressed as long-term or short-term concentrations for six key air pollutants: PM2.5, PM10, ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide. In addition, the guidelines provide interim targets to guide reduction efforts of these pollutants, as well as good practice statements for the management of certain types of PM (i.e., black carbon/elemental carbon, ultrafine particles, particles originating from sand and duststorms). These guidelines are not legally binding standards; however, they provide WHO Member States with an evidence-informed tool, which they can use to inform legislation and policy. Ultimately, the goal of these guidelines is to help reduce levels of air pollutants in order to decrease the enormous health burden resulting from the exposure to air pollution worldwide.

Basic Leucine Zipper Transcription Factors Advances In Research And Application 2011 Edition

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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09

Basic Leucine Zipper Transcription Factors Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.

Basic-Leucine Zipper Transcription Factors: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Basic-Leucine Zipper Transcription Factors in a compact format. The editors have built Basic-Leucine Zipper Transcription Factors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Basic-Leucine Zipper Transcription Factors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Basic-Leucine Zipper Transcription Factors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Adverse Drug Reactions

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Author : Jack Uetrecht
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-18

Adverse Drug Reactions written by Jack Uetrecht and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-18 with Medical categories.

This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug reactions. There is also a description of several examples of ADRs that serve to illustrate specific aspects of ADR mechanisms. Eventually the book shows that ultimately better methods are needed to predict which drug candidates are likely to cause ADRs and which patients are at increased risk. But at present research seems to be far from this goal.

Transcription Factors In Blood Cell Development

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Author : Tilman Borggrefe
language : en
Publisher: Springer Nature
Release Date : 2024-07-17

Transcription Factors In Blood Cell Development written by Tilman Borggrefe and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-17 with Science categories.

This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that contain a part of a transcription factor. In the given chapters covering each one particular example, the function of transcription factors is characterized in normal as well as leukemic contexts. New technologies such as ChIP-Seq or RNA-Seq, that make use of genome-wide sequencing, have shown that such master regulators of blood cell development often work in combinatorial fashion and, when dysregulated, results in leukemogenesis. This book is not only intended for experts but it should also be a useful resource for younger scientists or scientists from other disciplines, who may use this book as a stimulating starting point for further discoveries and/ or translational endeavors.

Encyclopedia Of Signaling Molecules

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Author : Sangdun Choi
language : en
Publisher: Springer
Release Date : 2017-12-15

Encyclopedia Of Signaling Molecules written by Sangdun Choi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-15 with Medical categories.

The second edition of this encyclopedia presents over 400 biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts. The molecules are described by recognized leaders in each molecule. The interactions of these single molecules in signal transduction networks will also be explored. This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike. Currently, there are more than 30,000 genes in human genome. However, not all the proteins encoded by these genes work equally in order to maintain homeostasis. Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities.