The Science And Applications Of Microbial Genomics

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The Science And Applications Of Microbial Genomics

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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2013-05-02

The Science And Applications Of Microbial Genomics written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-02 with Science categories.

Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us. On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.

The Science And Applications Of Synthetic And Systems Biology

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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2011-12-30

The Science And Applications Of Synthetic And Systems Biology written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-30 with Science categories.

Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Microbial Genomes

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Author : Claire M. Fraser
language : en
Publisher: Humana Press
Release Date : 2010-12-09

Microbial Genomes written by Claire M. Fraser and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-09 with Science categories.

This collection of diverse articles by the pioneers of modern genomics takes stock of the current state of the field and elucidates the contribution that sequencing genomes has made to our understanding of microbial metabolism and evolution. Through twenty-eight thought-provoking chapters, the authors describe some of the most common computational methods and their applications to studying pathogenic microorganisms, show how genomics can be used to reconstruct the history and dynamism of the microbial world, and discuss issues as diverse as reconstruction of metabolic pathways, cell cycle processes, microbial evolution, metagenomics, and vaccine development. Additional chapters deal with microarrays and expression analysis and the role of genomic in drug discovery.

Microbial Diversity In The Genomic Era

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Author : Surajit Das
language : en
Publisher: Academic Press
Release Date : 2018-09-20

Microbial Diversity In The Genomic Era written by Surajit Das and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-20 with Science categories.

Microbial Diversity in the Genomic Era presents insights on the techniques used for microbial taxonomy and phylogeny, along with their applications and respective pros and cons. Though many advanced techniques for the identification of any unknown bacterium are available in the genomics era, a far fewer number of the total microbial species have been discovered and identified to date. The assessment of microbial taxonomy and biosystematics techniques discovered and practiced in the current genomics era with suitable recommendations is the prime focus of this book. - Discusses the techniques used for microbial taxonomy and phylogeny with their applications and respective pros and cons - Reviews the evolving field of bacterial typing and the genomic technologies that enable comparative analysis of multiple genomes and the metagenomes of complex microbial environments - Provides a uniform, standard methodology for species designation

Computing For Comparative Microbial Genomics

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Author : David Wayne Ussery
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-02-26

Computing For Comparative Microbial Genomics written by David Wayne Ussery and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-26 with Science categories.

Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.

Microbial Genomics In Sustainable Agroecosystems

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Author : Vijay Tripathi
language : en
Publisher: Springer Nature
Release Date : 2019-11-23

Microbial Genomics In Sustainable Agroecosystems written by Vijay Tripathi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-23 with Science categories.

Today, microbiology is a rapidly growing discipline in the life sciences, and the technologies are evolving on a virtually daily basis. Next-generation sequencing technologies have revolutionized microbial analysis, and can help us understand the biology and genomic diversity of various bacterial species with significant impacts on agro-ecosystems. In addition, advances in molecular biology and microbiology techniques hold the potential to improve the productivity and sustainability of agriculture and forestry. This new volume addresses the role of microbial genomics in understanding the living systems that exist in the soil and their interactions with plants, an aspect that is also important for crop improvement. The topics covered focus on a deeper and clearer understanding of how microbes cause diseases, the genome-based development of novel antibacterial agents and vaccines, and the role of microbial genomics in crop improvement and agroforestry. Given its scope, the book offers a valuable resource for researchers and students of agriculture and infectious biology.

Metagenomics For Microbiology

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Author : Jacques Izard
language : en
Publisher: Academic Press
Release Date : 2025-09-01

Metagenomics For Microbiology written by Jacques Izard and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-09-01 with Science categories.

Metagenomics for Microbiology, Second Edition unveils the intricate and diverse world of microbial communities, emphasizing their critical roles in health, disease, and ecosystem functionality. This updated edition addresses the significant challenges in the field and introduces promising approaches to make metagenomics research more feasible. Through comprehensive revisions and over five new chapters, readers are equipped with the latest research data and analyses, advancing their understanding of microbial principles. Notably, this edition provides a robust foundation for the design and analysis of omics studies, focusing on technological underpinnings and practical applications. It remains an essential resource for characterizing microbial consortia. - Describes updated methodologies with best-practice prescription, from sample to data analysis, for current metagenomic studies - Updates on sample preparation, data production, data clean up, data analysis, statistics, and experimental biology, with accompanying descriptions - Includes a new chapter on long read applications using Nanopore technology - Provides a new chapter on probability distributions that underpin the structure of microbiome ecosystems - Covers bio surveillance of diseases and biodefense

Functional Microbial Genomics

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Author : Brendan Wren
language : en
Publisher:
Release Date : 2003

Functional Microbial Genomics written by Brendan Wren and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.

Functional Microbial Genomics, edited by two leading experts in the field, provides the researcher with an up-to-date collection of articles on post-genome technologies central to studying the function of microorganisms.Since the release of the first complete genome sequence of a free-living organ

The Science And Applications Of Microbial Genomics

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Author :
language : en
Publisher:
Release Date : 2013

The Science And Applications Of Microbial Genomics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.

On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.--Résumé de l'éditeur.

Marine Microbiology

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Author : Colin B. Munn
language : en
Publisher: CRC Press
Release Date : 2019-11-26

Marine Microbiology written by Colin B. Munn and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-26 with Science categories.

The third edition of this bestselling text has been rigorously updated to reflect major new discoveries and concepts since 2011, especially progress due to extensive application of high-throughput sequencing, single cell genomics and analysis of large datasets. Significant advances in understanding the diversity and evolution of bacteria, archaea, fungi, protists, and viruses are discussed and their importance in marine processes is explored in detail. Now in full colour throughout, all chapters have been significantly expanded, with many new diagrams, illustrations and boxes to aid students’ interest and understanding. Novel pedagogy is designed to encourage students to explore current high-profile research topics. Examples include the impacts of rising CO2 levels on microbial community structure and ocean processes, interactions of microbes with plastic pollution, symbiotic interactions, and emerging diseases of marine life. This is the only textbook addressing such a broad range of topics in the specific area of marine microbiology, now a core topic within broader Marine Science degrees. A Companion Website provides additional online resources for instructors and students, including a summary of key concepts and terminology for each chapter, links to further resources, and flashcards to aid self-assessment.