The Systemic Response To Injury
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The Systemic Response To Injury
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Author : Walter Reed Army Institute of Research
language : en
Publisher:
Release Date : 1955
The Systemic Response To Injury written by Walter Reed Army Institute of Research and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1955 with Korean War, 1950-1953 categories.
Inflammation And The Microcirculation
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Author : D. Neil Granger
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2010
Inflammation And The Microcirculation written by D. Neil Granger and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Hot Topics In Burn Injuries
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Author : Selda Pelin Kartal
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-05-23
Hot Topics In Burn Injuries written by Selda Pelin Kartal and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-23 with Medical categories.
The aim of this book is to give readers a broad review of burn injuries, which may affect people from birth to death and can lead to high morbidity and mortality. The book consists of four sections and seven chapters. The first section consists of the introductory review chapter, which overviews the burn injuries. The second section includes chapter "Burn Etiology and Pathogenesis," which focuses on burn injuries and clinical findings. The third section consists of chapter "Controlling Inflammation in Burn Injury" and is devoted to the role of inflammatory response, which is fundamental to the healing process, while a prolonged inflammation may lead to scarring and fibrosis. The fourth section consists of four chapters as follows: "Therapeutic Effects of Conservative Treatments on Burn Scars," "Herbal Therapy for Burns and Burn Scars," "Platelet-Rich Plasma in Burn Treatment," and "Surgical Treatment of Burn Scars." The book is easy to read and includes hot topics on burn injury to enhance the reader's understanding and knowledge.
Clinical Foundations Of Musculoskeletal Medicine
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Author : Robert J. Esther
language : en
Publisher: Springer Nature
Release Date : 2021-07-22
Clinical Foundations Of Musculoskeletal Medicine written by Robert J. Esther and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-22 with Medical categories.
Musculoskeletal (MSK) disorders have a high prevalence and are one of the main reasons for patients to consult with a provider. For a range of issues from injury to back pain to rheumatic disease, musculoskeletal pathology is the second most common reason for a patient to see a primary care provider. However, despite their prevalence and significant socioeconomic impact, musculoskeletal disorders are relatively undertaught in medical schools in the United States. While all medical, nursing and physician assistant students receive exposure to some MSK content, in many medical schools this material does not receive curricular exposure commensurate with its prevalence. This practical textbook fills in that gap. All aspects of musculoskeletal disease and its management are presented concisely for quick reference and review, with each chapter opening with clear goals and objectives. The text begins with a discussion of the anatomy and physiology of bone, cartilage and muscle, including imaging techniques and interpretation. Musculoskeletal infections, tumors and vascular conditions are then covered, along with common rheumatic conditions such as rheumatoid and osteoarthritis, metabolic bone disease, and age-specific and traumatic conditions. Finally, the upper and lower extremity and spine are thoroughly discussed in terms of anatomy/pathoanatomy, common clinical conditions, physical exam, and common radiographic and clinical correlations. The main audience for Clinical Foundations of Musculoskeletal Medicine is medical students seeking to improve their understanding of common musculoskeletal conditions. Given the relevance of musculoskeletal conditions to a range of providers, this book can also be used for the musculoskeletal education of allied professionals such as physician assistants (PA) and nurse practitioner students. It could likewise serve as a resource for practicing medical professionals to develop and enhance their knowledge in this content area.
Surgical Metabolism
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Author : Kimberly A. Davis
language : en
Publisher: Springer
Release Date : 2014-07-22
Surgical Metabolism written by Kimberly A. Davis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-22 with Medical categories.
This volume is a comprehensive, state-of-the-art review for clinicians with an interest in the peri-operative nutritional management of all surgical patients. The text reviews normal physiology, the pathophysiology of starvation and surgical stressors, and focuses on appropriate nutritional repletion for various common disease states. Specifically, the text addresses the severe metabolic demands created by systemic inflammation, infection, and major insults such as trauma and burns. In addition, the book addresses the growing problem of obesity in surgical populations, including appropriate strategies directed towards the metabolic management of these patients. The text is designed for clinicians across levels of training and provides clear and concise evidence based guidelines for the metabolic management and nutritional support of the surgical patient. Written by experts in the field, Surgical Metabolism: The Metabolic Care of the Surgical Patient is a valuable resource for all clinicians involved in the care of the critically ill.
Vasoplegic Endothelial Dysfunction
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Author : Paulo Roberto Barbosa Evora
language : en
Publisher: Springer Nature
Release Date : 2021-05-31
Vasoplegic Endothelial Dysfunction written by Paulo Roberto Barbosa Evora and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-31 with Medical categories.
This unique work presents one of the most significant organ failure condition – cardiocirculatory shock – and the prominent role of Methylene Blue (MB). Through their extensive experience, the authors’ consider that the lifesaving feature of MB is still underestimated. For this reason they outline key concepts of MB, mentioning essential experimental data, yet focusing mainly on its application in the care of critically ill patients. In an easy-to-read format, the 18 chapters were organized in a didactically structured order, distributed in four parts. The first part introduces the general conceptual aspects and physiology of the endothelium. The second part presents the particularities of endothelial dysfunction in different types of shock. Methylene blue is discussed in detail in the third part. In the fourth part, particular situations of endothelial dysfunction, such as heart surgery and organ transplantation, are described. Additionally, the two complementary subjects of acid-base balance and the therapeutic use of inhaled nitric oxide are mentioned. Finally, looking for therapeutic alternatives for what we classify as "vasoplegic endothelial dysfunction", MB remains promising as an adjuvant to sympathomimetic amines. The combination of three recently proposed concepts may be useful in obtaining better results against the high mortality rates in critically ill patients. These three concepts are "wide-spectrum vasopressors", vasopressor economy strategies, and microcirculation protection against the harmful effects of using high concentrations of amines. This book ́s translational approach will appeal to a variety of readers within the health specialties of medicine, biomedicine, physiotherapy, nursing, odontology, and basic science.
Complications In Anesthesia
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Author : John L. Atlee
language : en
Publisher: Elsevier Health Sciences
Release Date : 2007-01-01
Complications In Anesthesia written by John L. Atlee and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-01 with Medical categories.
Practical text focuses on complications in the practice of anesthesia. Divided into sections similar to the thought processes involved in decision-making. Thumb indexing and cross-references are also included. All chapters have a case synopsis, problem analysis, and discussion of management and prevention.
The Resolution Of Inflammation
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Author : Adriano Rossi
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-17
The Resolution Of Inflammation written by Adriano Rossi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-17 with Medical categories.
This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Common Surgical Diseases
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Author : Jonathan A. Myers
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Common Surgical Diseases written by Jonathan A. Myers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.
In a concise manner, this book presents common surgical problems encountered by medical students and residents. The book provides easy access for residents before teaching rounds, lectures, etc. The algorithm approach lends itself to rapid learning, making the book a must for every surgical resident.
Sepsis And Organ Dysfunction
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Author : A.E. Baue
language : en
Publisher: Springer
Release Date : 2000
Sepsis And Organ Dysfunction written by A.E. Baue and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
An experienced physician knows how to recognize a patient suffering from sepsis, but cannot accurately determine whether the patient will survive. Cardinal elements of the treatment for sepsis include specific antibiotic and vasoactive drugs, enteral and parenteral nutrition, artificial respiration, and optimization of the oxygen transport to tissues. Nonetheless, with a certain frequency, these techniques are insufficient to ensure the recovery of a critically ill patient, especially when it is necessary to overcome functional alterations subsequent to organ and vital-system overload. The key elements in the progression of the sepsis-MODS syndrome are tied to numerous factors. These include: the severity and location of the lesion; the patient's age; the remaining functional reserve; the presence of mediatory which may be stimulatory, inhibitory or both.