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Three Dimensonal Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis


Three Dimensonal Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis
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Three Dimensional Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis


Three Dimensional Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis
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Author : Minming Huang
language : en
Publisher:
Release Date : 2004

Three Dimensional Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis written by Minming Huang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Electronic dissertations categories.


This dissertation focuses on the study of three-dimensional near-infrared (NIR) imaging reconstruction using ultrasound localization for breast cancer detection and diagnosis. With the 3D NIR forward model for reflection geometry built and investigated, successful reconstruction of both absorption and scattering coefficients has been obtained and evaluated using both a phantom study and initial clinic data. In this work, we first introduce a dual mesh optical reconstruction method with depth correction using a priori ultrasound information. It can significantly improve the reconstructed absorption distributions in deeper target layers. Clinical results have shown improved correlation between reconstructed total hemoglobin concentrations and the histological micorvessel density counts. Next, a combined Tikhonov regularization and dual mesh scheme based on finite element method (FEM) is proposed to solve the inter-parameter cross talk between the scattering coefficient and absorption coefficient. In this approach, the optimal regularization factor is given by the standard L-curve. Different regularization factors have been assigned to the target region and non-target region to incorporate the priori target information from the co-registered ultrasound images. Both phantom experiments and clinic examples have shown that this new approach has the ability to reconstruct the absorption and diffusion coefficients simultaneously, and the reconstructed target absorption and diffusion maps have no depth dependence effect. Finally, a simple two-layer model is generated and studied to solve a clinical issue related to the chest wall, which is a mixture of bones and muscles. For small breasts, the chest wall appears within 2–3 cm distance from the skin surface. As a result, the simple one layer model is not accurate. Furthermore, for some cases, there is also an obvious chest wall mismatch between the reference site and lesion site. To solve this clinical issue, a simplified two-layer model is generated and a fitting method is adopted to estimate the optical properties of both layers. Then a correction method is applied to correct for the chest wall mismatch between the lesion site and reference site. With this scheme, phantom targets located on top of the chest wall phantom layer can be reconstructed with good contrast and resolution.



Three Dimensonal Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis


Three Dimensonal Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis
DOWNLOAD
Author : Minming Huang
language : en
Publisher:
Release Date : 2005

Three Dimensonal Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis written by Minming Huang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.




Three Dimensional Ultrasound Imaging And Its Applications In Combined Near Infrared Optical Imaging And Co Registered Photoacoustic Imaging


Three Dimensional Ultrasound Imaging And Its Applications In Combined Near Infrared Optical Imaging And Co Registered Photoacoustic Imaging
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Author : Puyun Guo
language : en
Publisher:
Release Date : 2007

Three Dimensional Ultrasound Imaging And Its Applications In Combined Near Infrared Optical Imaging And Co Registered Photoacoustic Imaging written by Puyun Guo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.


This dissertation focuses on three-dimensional (3-D) ultrasound and its applications as an adjunct modality for biomedical optical imaging.



Mammography And Beyond


Mammography And Beyond
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2001-06-04

Mammography And Beyond written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-04 with Medical categories.


X-ray mammography screening is the current mainstay for early breast cancer detection. It has been proven to detect breast cancer at an earlier stage and to reduce the number of women dying from the disease. However, it has a number of limitations. These current limitations in early breast cancer detection technology are driving a surge of new technological developments, from modifications of x-ray mammography such as computer programs that can indicate suspicious areas, to newer methods of detection such as magnetic resonance imaging (MRI) or biochemical tests on breast fluids. To explore the merits and drawbacks of these new breast cancer detection techniques, the Institute of Medicine of the National Academy of Sciences convened a committee of experts. During its year of operation, the committee examined the peer-reviewed literature, consulted with other experts in the field, and held two public workshops. In addition to identifying promising new technologies for early detection, the committee explored potential barriers that might prevent the development of new detection methods and their common usage. Such barriers could include lack of funding from agencies that support research and lack of investment in the commercial sector; complicated, inconsistent, or unpredictable federal regulations; inadequate insurance reimbursement; and limited access to or unacceptability of breast cancer detection technology for women and their doctors. Based on the findings of their study, the committee prepared a report entitled Mammography and Beyond: Developing Technology for Early Detection of Breast Cancer, which was published in the spring of 2001. This is a non-technical summary of that report.



Breast Cancer Diagnosis Using Ultrasound And Diffusive Light


Breast Cancer Diagnosis Using Ultrasound And Diffusive Light
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Author :
language : en
Publisher:
Release Date : 2001

Breast Cancer Diagnosis Using Ultrasound And Diffusive Light written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.


We have developed a novel near-infrared optical technique with ultrasound localization. During the last year, we have made significant progress on using our technique to improve breast cancer diagnosis. Initial results with a group of biopsied patients have shown that early stage invasive cancers present two-fold greater total hemoglobin concentration than fibroadenomas and benign lesions. Initial results of advanced cancers have shown good correlation between cancer angiogenesis distributions imaged by the hybrid imaging technique and histological microvessel density counts. We believe our unique has a great potential to improve current practice on breast cancer diagnosis and monitor treatment responses of advanced cancers.



Photoacoustic Tomography


Photoacoustic Tomography
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Author : Minghua Xu
language : en
Publisher: CRC PressI Llc
Release Date : 2014-09-30

Photoacoustic Tomography written by Minghua Xu and has been published by CRC PressI Llc this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-30 with Technology & Engineering categories.




Optical Imaging Of Breast Cancers


Optical Imaging Of Breast Cancers
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Author : Yan Xu
language : en
Publisher:
Release Date : 2013

Optical Imaging Of Breast Cancers written by Yan Xu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.




Developing Technologies For Early Detection Of Breast Cancer


Developing Technologies For Early Detection Of Breast Cancer
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2000-07-06

Developing Technologies For Early Detection Of Breast Cancer written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-07-06 with Medical categories.


In November 1999, the Institute of Medicine, in consultation with the Commission on Life Sciences, the Commission on Physical Sciences, Mathematics, and Applications, and the Board on Science, Technology and Economic Policy launched a one year study on technologies for early detection of breast cancer. The committee was asked to examine technologies under development for early breast cancer detection, and to scrutinize the process of medical technology development, adoption, and dissemination. The committee is gathering information on these topics for its report in a number of ways, including two public workshops that bring in outside expertise. The first workshop on "Developing Technologies for Early Breast Cancer Detection" was held in Washington DC in February 2000. The content of the presentations at the workshop is summarized here. A second workshop, which will focus on the process of technology development and adoption, will be held in Washington, DC on June 19-20. A formal report on these topics, including conclusions and recommendations, will be prepared by the committee upon completion of the one-year study.



Evaluation Of Near Infrared Contrast Agents For Cancer Detection Using Optical Imaging Techniques


Evaluation Of Near Infrared Contrast Agents For Cancer Detection Using Optical Imaging Techniques
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Author : Akram Abuteen
language : en
Publisher:
Release Date : 2016

Evaluation Of Near Infrared Contrast Agents For Cancer Detection Using Optical Imaging Techniques written by Akram Abuteen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.




Photoacoustic Imaging


Photoacoustic Imaging
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Author : Reda Gharieb
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-05-06

Photoacoustic Imaging written by Reda Gharieb and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-06 with Technology & Engineering categories.


Photoacoustic imaging (PAI) is an emerging non-invasive imaging modality that integrates the advantages of deep ultrasound penetration and high optical contrast. It provides better resolution than pure ultrasonic imaging and deeper penetration than pure optical imaging. Hence, it is opening new frontiers in diagnostic imaging. Photoacoustic Imaging - Principles, Advances and Applications, provides interested readers with the principle knowledge, advanced methodologies, and new applications associated with PAI technology. Written by expert researchers, chapters cover such topics as the generation and detection of photoacoustic signals, sound source localization, image reconstruction and formation, and application of PAI in gastroenterology and ophthalmology.