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Optical Imaging Of Breast Cancers


Optical Imaging Of Breast Cancers
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Optical Imaging Of Breast Cancers


Optical Imaging Of Breast Cancers
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Author : Yan Xu
language : en
Publisher:
Release Date : 2013

Optical Imaging Of Breast Cancers written by Yan Xu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.




Optical Detection Of Cancer


Optical Detection Of Cancer
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Author : Arlen D. Meyers
language : en
Publisher: World Scientific
Release Date : 2012

Optical Detection Of Cancer written by Arlen D. Meyers and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.


Ch. 1. The optical detection of cancer: an introduction / Toby Steele and Arlen Meyers -- ch. 2. Optical coherence tomography in oral cancer / Shahareh Sabet and Petra Wilder-Smith -- ch. 3. Optical coherence tomography in laryngeal cancer / Marcel Kraft and Christoph Arens -- ch. 4. Fluorescence imaging of the upper aerodigestive tract / Christian Stephan Betz, Andreas Leunig and Christoph Arens -- ch. 5. Photodynamic diagnosis and photodynamic therapy techniques / Zheng Huang -- ch. 6. OCT detection of lung cancer / S. Murgu and M. Brenner -- ch. 7. Diffuse optical spectroscopy and imaging in breast cancer / Albert E. Cerussi and Bruce J. Tromberg -- ch. 8. OCT for skin cancer / Gordon McKenzie and Adam Meekings



Optical Imaging Of Mammaglobin Expression Of Breast Cancer


Optical Imaging Of Mammaglobin Expression Of Breast Cancer
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Author :
language : en
Publisher:
Release Date : 2003

Optical Imaging Of Mammaglobin Expression Of Breast Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.


Mammaglobin (MMG) is a breast-specific glycoprotein that is over-expressed in 80% of all primary and metastatic breast cancer. Despite its uniqueness as a breast-specific cancer marker, the utility of MMG in breast cancer imaging has not been explored. Consequently, the goal of this project is to evaluate the potential of imaging the expression of MMG in established human breast cancer models. TO accomplish this goal, we labeled polyclonal and monoclonal anti-MMG antibodies with a near infrared fluorescent probe for optical imaging and 64Cu-DOTA for positron emission tomography (mPET). Preliminary results indicate that the mPET imaging with 64Cu-DOTA-anti MMG monoclonal antibodies showed predominant liver uptake in mice. In contrast, the fluorescent-labeled derivative of polyclonal MMG antibody primarily accumulated in the tumor, kidneys and liver. We have also developed a tumor model with increased expression of MMG. Our preliminary results appear to support the hypothesis that targeting the expression of MMG will enhance the localization of breast cancer tumors.



Optical Imaging Of Cancer


Optical Imaging Of Cancer
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Author : Eben Rosenthal
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-03

Optical Imaging Of Cancer written by Eben Rosenthal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-03 with Medical categories.


To describe principles of optical imaging including chemistry and physics of fluorescence, limitations/advantages of optical imaging compared to metabolic and anatomic imaging. Describe hardware adapted for small animal imaging and for clinical applications: endoscopes and operative microscopes. Outline FDA approved and newer optical imaging probes. Include discussion of chemistry and linkage to other proteins. Review current techniques to image cancer and the development of techniques to specifically image cancer cells. Review use of exploiting differences in tissue autofluorescence to diagnose and treat cancer. Include agents such as 5-aminoleculinic acid. Review mechanisms that require proteolytic processing within the tumor to become active fluorophores. Review use of cancer selective proteins to localize probes to cancer cells: include toxins, antibodies, and minibodies. Introduction of plasmids, viruses or other genetic material may be used to express fluorescent agents in vivo. This chapter will review multiple vectors and delivery mechanisms of optical imaging cassettes.Preclinical investigations into the use of optical contrast agents for the detection of primary tumors in conventional and orthotopic models will be discussed. Preclinical investigations into the use of optical contrast agents for the detection of metastatic tumors in mouse models will be discussed. Use of targeted and non-specific optical contrast agents have been used for the detection of sentinel lymph node detection. These applications and how they differ from other applications will be discussed. Because of the unique difficulty of identifying tumor from normal tissue in brain tissue, a separate chapter would be needed. More clinical data is available for this cancer type than any other. Discussion of potential clinical applications for optical imaging and an assessment of the potential market.



Diagnostic Optical Imaging Of Breast Cancer From Animal Models To First In Men Studies


Diagnostic Optical Imaging Of Breast Cancer From Animal Models To First In Men Studies
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Author : Michel Eisenblätter
language : en
Publisher:
Release Date : 2011

Diagnostic Optical Imaging Of Breast Cancer From Animal Models To First In Men Studies written by Michel Eisenblätter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.




Physics Of Mammographic Imaging


Physics Of Mammographic Imaging
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Author : Mia K. Markey
language : en
Publisher: CRC Press
Release Date : 2012-11-09

Physics Of Mammographic Imaging written by Mia K. Markey and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-09 with Science categories.


Due to the increasing number of digital mammograms and the advent of new kinds of three-dimensional x-ray and other forms of medical imaging, mammography is undergoing a dramatic change. To meet their responsibilities, medical physicists must constantly renew their knowledge of advances in medical imaging or radiation therapy, and must be prepared to function at the intersection of these two fields. Physics of Mammographic Imaging gives an overview on the current role and future potential of new alternatives to mammography in the context of clinical need, complementary approaches, and ongoing research. This book provides comprehensive coverage on the fundamentals of image formation, image interpretation, analysis, and modeling. It discusses the use of mammographic imaging in the detection, diagnosis, treatment planning, and monitoring of breast cancer. Expert authors give a balanced summary of core topics such as digital mammography, contrast-enhanced mammography, stereomammography, breast tomosynthesis, and breast CT. The book highlights the use of mammographic imaging with complementary breast imaging modalities such as ultrasound, MRI, and nuclear medicine techniques. It discusses critical issues such as computer-aided diagnosis, perception, and quality assurance. This is an exciting time in the development of medical imaging, with many new technologies poised to make a substantial impact on breast cancer care. This book will help researchers and students get up to speed on crucial developments and contribute to future advances in the field.



Advances In Optical Biopsy And Optical Mammography


Advances In Optical Biopsy And Optical Mammography
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Author : Robert R. Alfano
language : en
Publisher:
Release Date : 1998

Advances In Optical Biopsy And Optical Mammography written by Robert R. Alfano and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.


Proceedings of a conference by the New York Academy of Sciences held in 1997. The papers explore optical biopsy and optical mammography - new techniques that allow investigators to determine whether a tissue is cancerous without using invasive techniques. The text offers an analysis of the spectrum light emitted from optically excited tissue which allows investigators to detect physical and chemical changes in tissue and determine whether the tissue is normal, benign or cancerous.



Breast Cancer


Breast Cancer
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Author : Susan Done
language : en
Publisher: IntechOpen
Release Date : 2011-12-14

Breast Cancer written by Susan Done and has been published by IntechOpen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-14 with Medical categories.


In recent years it has become clear that breast cancer is not a single disease but rather that the term encompasses a number of molecularly distinct tumors arising from the epithelial cells of the breast. There is an urgent need to better understand these distinct subtypes and develop tailored diagnostic approaches and treatments appropriate to each. This book considers breast cancer from many novel and exciting perspectives. New insights into the basic biology of breast cancer are discussed together with high throughput approaches to molecular profiling. Innovative strategies for diagnosis and imaging are presented as well as emerging perspectives on breast cancer treatment. Each of the topics in this volume is addressed by respected experts in their fields and it is hoped that readers will be stimulated and challenged by the contents.



Concurrent Mr Nir Imaging For Breast Cancer Diagnosis


Concurrent Mr Nir Imaging For Breast Cancer Diagnosis
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Author :
language : en
Publisher:
Release Date : 2005

Concurrent Mr Nir Imaging For Breast Cancer Diagnosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.


The primary objective of this research program is to investigate concurrent near infrared (NTR) optical and magnetic resonance (MR) imaging for breast cancer diagnosis. The NIR diffuse optical imaging offers novel criteria for cancer differentiation with the ability to measure (in vivo) oxygenation and vascularization state, the uptake and release of contrast agents and chromophore concentrations with high sensitivity. However, NIR diffuse optical tomography is inherently a low spatial resolution imaging modality due to diffuse nature of light photons. Alternatively, MRI provides high spatial resolution with excellent tissue discrimination, but has limited ability to monitor hemoglobin dynamics and other contrast mechanisms that optical imaging provides. Therefore, concurrent MRI-NIR optical imaging brings together the most advantageous aspects of the two imaging modalities for breast cancer diagnosis.



Three Dimensonal Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis


Three Dimensonal Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis
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Author : Minming Huang
language : en
Publisher:
Release Date : 2005

Three Dimensonal Near Infrared Optical Imaging Using Ultrasound Guidance For Breast Cancer Detection And Diagnosis written by Minming Huang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.