Optical Detection Of Cancer
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Optical Detection Of Cancer
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Author : Arlen D. Meyers
language : en
Publisher: World Scientific
Release Date : 2012
Optical Detection Of Cancer written by Arlen D. Meyers and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Ch. 1. The optical detection of cancer: an introduction / Toby Steele and Arlen Meyers -- ch. 2. Optical coherence tomography in oral cancer / Shahareh Sabet and Petra Wilder-Smith -- ch. 3. Optical coherence tomography in laryngeal cancer / Marcel Kraft and Christoph Arens -- ch. 4. Fluorescence imaging of the upper aerodigestive tract / Christian Stephan Betz, Andreas Leunig and Christoph Arens -- ch. 5. Photodynamic diagnosis and photodynamic therapy techniques / Zheng Huang -- ch. 6. OCT detection of lung cancer / S. Murgu and M. Brenner -- ch. 7. Diffuse optical spectroscopy and imaging in breast cancer / Albert E. Cerussi and Bruce J. Tromberg -- ch. 8. OCT for skin cancer / Gordon McKenzie and Adam Meekings
Multimodal Optical Diagnostics Of Cancer
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Author : Valery V. Tuchin
language : en
Publisher: Springer Nature
Release Date : 2020-10-23
Multimodal Optical Diagnostics Of Cancer written by Valery V. Tuchin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-23 with Medical categories.
This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination. Coverage includes detailed descriptions of modern state of design for novel methods of optical non-invasive cancer diagnostics; multi-modal methods for earlier cancer diagnostic enhancing the probability of effective cancer treatment; modern clinical trials with novel methods of clinical cancer diagnostics; medical and technical aspects of clinical cancer diagnostics, and long-term monitoring. Biomedical engineers, cancer researchers, and scientists will find the book to be an invaluable resource. Introduces optical imaging strategies; Focuses on multimodal optical diagnostics as a fundamental approach; Discusses novel methods of optical non-invasive cancer diagnostics.
Optical Imaging Of Cancer
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Author : Eben Rosenthal
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-03
Optical Imaging Of Cancer written by Eben Rosenthal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-03 with Medical categories.
To describe principles of optical imaging including chemistry and physics of fluorescence, limitations/advantages of optical imaging compared to metabolic and anatomic imaging. Describe hardware adapted for small animal imaging and for clinical applications: endoscopes and operative microscopes. Outline FDA approved and newer optical imaging probes. Include discussion of chemistry and linkage to other proteins. Review current techniques to image cancer and the development of techniques to specifically image cancer cells. Review use of exploiting differences in tissue autofluorescence to diagnose and treat cancer. Include agents such as 5-aminoleculinic acid. Review mechanisms that require proteolytic processing within the tumor to become active fluorophores. Review use of cancer selective proteins to localize probes to cancer cells: include toxins, antibodies, and minibodies. Introduction of plasmids, viruses or other genetic material may be used to express fluorescent agents in vivo. This chapter will review multiple vectors and delivery mechanisms of optical imaging cassettes.Preclinical investigations into the use of optical contrast agents for the detection of primary tumors in conventional and orthotopic models will be discussed. Preclinical investigations into the use of optical contrast agents for the detection of metastatic tumors in mouse models will be discussed. Use of targeted and non-specific optical contrast agents have been used for the detection of sentinel lymph node detection. These applications and how they differ from other applications will be discussed. Because of the unique difficulty of identifying tumor from normal tissue in brain tissue, a separate chapter would be needed. More clinical data is available for this cancer type than any other. Discussion of potential clinical applications for optical imaging and an assessment of the potential market.
Optical Spectroscopy And Imaging For Cancer Diagnostics Fundamentals Progress And Challenges
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Author : Noureddine Melikechi
language : en
Publisher: World Scientific
Release Date : 2023-01-06
Optical Spectroscopy And Imaging For Cancer Diagnostics Fundamentals Progress And Challenges written by Noureddine Melikechi and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-06 with Technology & Engineering categories.
This is an interdisciplinary book that presents the applications of novel laser spectroscopy and imaging techniques for the detection of cancers recently developed by some of the world's most renown researchers. The book consists of three parts and a total of 16 chapters. Each chapter is written by leading experts who are actively seeking to develop novel spectroscopic and analytical methods for cancer detection and diagnosis.In Part I, the authors present fundamentals on optics, atoms and molecules, biophysics, cancer and machine learning. These chapters are intended for those who are not experts in the field but wish to learn about fundamentals' aspects of some of the key topics that are addressed in this book. Particular attention has been given to providing key references for those who wish to go further into the fundamental aspects of atoms and molecules, light-matter interaction, optical instrumentation, machine learning and cancer.In Part II, the authors present key applications of various laser spectroscopic methods in cancer diagnosis. They have provided recent progress in cancer diagnostics obtained by combining laser spectroscopy and machine learning for the analysis of the spectra acquired from biomedical tissues and biofluids.In Part III, the authors present chapters that discuss key developments in the applications of various laser imaging techniques for cancer detection.This is one of the few books that addresses cancer detection and diagnosis using laser spectroscopic and imaging tools with an eye on providing the reader the scientific tools, including machine learning ones.
Novel Biosensors For Early Cancer Detection
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Author : Jeanne Elisabeth van Dongen
language : en
Publisher:
Release Date : 2022
Novel Biosensors For Early Cancer Detection written by Jeanne Elisabeth van Dongen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
Miniature And Molecularly Specific Optical Screening Technologies For Breast Cancer
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Author :
language : en
Publisher:
Release Date : 2009
Miniature And Molecularly Specific Optical Screening Technologies For Breast Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
The goal of this proposal is to harness the power of light to create "miniature and molecularly specific optical technologies" for breast cancer diagnosis and detection. The miniature technologies will leverage on millimeter scale silicon detectors and LEDs to make compact devices that can be used in a practical clinical setting for breast cancer detection. The features that will be exploited for optical detection/diagnosis of breast cancer will include the physiological, structural and molecular alterations that accompany the transformation of a cell from a normal to malignant state. This proposal also focuses on using contrast agents, specifically aminolevulinic acid (ALA) induced protoporphyrin IX (PpIX) and NBDG, for the molecular detection of breast cancer.
Novel Optical Endoscopes For Early Cancer Diagnosis And Therapy
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Author : Dale Jonathan Waterhouse
language : en
Publisher: Springer
Release Date : 2019-07-09
Novel Optical Endoscopes For Early Cancer Diagnosis And Therapy written by Dale Jonathan Waterhouse and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-09 with Science categories.
This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications.
Non Invasive Optical Detection Of Epithelial Cancer Using Oblique Incidence Diffuse Reflectance Spectroscopy
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Author : Alejandro Garcia-Uribe
language : en
Publisher:
Release Date : 2010
Non Invasive Optical Detection Of Epithelial Cancer Using Oblique Incidence Diffuse Reflectance Spectroscopy written by Alejandro Garcia-Uribe and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
This dissertation describes the design, fabrication and testing of an oblique incidence diffuse reflectance spectrometry (OIDRS) system for in-vivo and noninvasive detection of epithelial cancer. Two probes were fabricated using micromachining technology, which plays a significant role in the probe development by enabling device miniaturization, low-cost fabrication and precise assembly. The fist probe was developed and clinically tested for skin cancer detection. This probe consists of three source fibers, two linear array of collection fibers and four micromachined positioning devices for accurate alignment of the fibers. The spatially resolved diffuse reflectance spectra from 167 pigmented and 78 non-pigmented skin abnormalities were measured and used to design a set of classifiers to separate them into benign or malignant ones. These classifiers perform with an overall classification rate of 91%. The absorption and reduced scattering coefficient spectra were estimated to link the anatomic and physiologic properties of the lesions with the optical diagnosis. The melanoma cases presented larger average absorption and reduced scattering spectra than the dysplastic and benign ones. A second probe was designed to demonstrate the feasibility of a miniaturized?side viewing? optical sensor probe for OIDRS. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates. This miniaturize probe was used to measure twenty ex-vivo esophageal samples. Two statistical classifiers were designed to separate the esophageal cases. The first one distinguishes benign and low dysplastic from high dysplastic and cancerous lesions. The second classifier separates benign lesions from low dysplastic ones. Both classifiers generated a classification rate of 100%.
Optical Imaging For Cancer Detection And Characterization
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Author : Behnoosh Tavakoli
language : en
Publisher:
Release Date : 2012
Optical Imaging For Cancer Detection And Characterization written by Behnoosh Tavakoli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Optical Fluorescence Imaging Techniques For The Early Detection Of Cancer Of The Gastrointestinal Tract And Skin
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Author : Tracy McKechnie
language : en
Publisher:
Release Date : 2000
Optical Fluorescence Imaging Techniques For The Early Detection Of Cancer Of The Gastrointestinal Tract And Skin written by Tracy McKechnie and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.