Novel Optical Endoscopes For Early Cancer Diagnosis And Therapy


Novel Optical Endoscopes For Early Cancer Diagnosis And Therapy
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Novel Optical Endoscopes For Early Cancer Diagnosis And Therapy


Novel Optical Endoscopes For Early Cancer Diagnosis And Therapy
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Author : Dale Jonathan Waterhouse
language : en
Publisher: Springer
Release Date : 2019-07-09

Novel Optical Endoscopes For Early Cancer Diagnosis And Therapy written by Dale Jonathan Waterhouse and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-09 with Science categories.


This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications.



Multimodal Optical Diagnostics Of Cancer


Multimodal Optical Diagnostics Of Cancer
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Author : Valery V. Tuchin
language : en
Publisher: Springer Nature
Release Date : 2020-10-23

Multimodal Optical Diagnostics Of Cancer written by Valery V. Tuchin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-23 with Medical categories.


This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination. Coverage includes detailed descriptions of modern state of design for novel methods of optical non-invasive cancer diagnostics; multi-modal methods for earlier cancer diagnostic enhancing the probability of effective cancer treatment; modern clinical trials with novel methods of clinical cancer diagnostics; medical and technical aspects of clinical cancer diagnostics, and long-term monitoring. Biomedical engineers, cancer researchers, and scientists will find the book to be an invaluable resource. Introduces optical imaging strategies; Focuses on multimodal optical diagnostics as a fundamental approach; Discusses novel methods of optical non-invasive cancer diagnostics.



Optical Detection Of Cancer


Optical Detection Of Cancer
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Author : Arlen D. Meyers
language : en
Publisher: World Scientific
Release Date : 2012

Optical Detection Of Cancer written by Arlen D. Meyers and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.


Ch. 1. The optical detection of cancer: an introduction / Toby Steele and Arlen Meyers -- ch. 2. Optical coherence tomography in oral cancer / Shahareh Sabet and Petra Wilder-Smith -- ch. 3. Optical coherence tomography in laryngeal cancer / Marcel Kraft and Christoph Arens -- ch. 4. Fluorescence imaging of the upper aerodigestive tract / Christian Stephan Betz, Andreas Leunig and Christoph Arens -- ch. 5. Photodynamic diagnosis and photodynamic therapy techniques / Zheng Huang -- ch. 6. OCT detection of lung cancer / S. Murgu and M. Brenner -- ch. 7. Diffuse optical spectroscopy and imaging in breast cancer / Albert E. Cerussi and Bruce J. Tromberg -- ch. 8. OCT for skin cancer / Gordon McKenzie and Adam Meekings



Endoscopic Imaging Techniques And Tools


Endoscopic Imaging Techniques And Tools
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Author : Vani J.A. Konda
language : en
Publisher: Springer
Release Date : 2016-08-09

Endoscopic Imaging Techniques And Tools written by Vani J.A. Konda and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-09 with Medical categories.


This book is a comprehensive, state-of-the art update of the field of endoscopic imaging. The approaches to novel imaging and cutting edge techniques are demonstrated in the context of gastrointestinal endoscopic imaging, with discussions on both techniques in use and exploration of novel imaging platforms on the horizon in gastrointestinal endoscopy. Designed to convey practical information on these innovative approaches in a user-friendly manner, each chapter focuses on the principals of the technology under discussion, highlights key clinical indications, demonstrates the equipment and set up required, covers the basic technique, and reviews complication profiles, and comparison to standard or alternative approaches. Chapters also provides the expert’s tips and tricks for the reader to more practically and easily translate the information provided into safe and successful practice. The volume is also accompanied by videos demonstrating highlighting certain techniques. Written by experts in the field, Endoscopic Imaging Techniques and Tools is a valuable resource for clinicians, trainees, and researchers interested in the field of endoscopic imaging.



Diagnostic Endoscopy


Diagnostic Endoscopy
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Author : Haishan Zeng
language : en
Publisher: Taylor & Francis
Release Date : 2013-12-09

Diagnostic Endoscopy written by Haishan Zeng and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-09 with Science categories.


Combining a professional development course on diagnostic endoscopy from SPIE (the international society advancing light-based research) and the authors’ graduate course on biomedical optics, this work is written for researchers in medical optics and biomedical engineering as well as graduate medical optics students. It uses extensive examples/case studies to familiarize readers with the basics of endoscopic optics, the pros and cons of white light endoscopy and fluorescence endoscopy for diagnostic applications, and various microscopic endoscopy imaging modalities. It covers basic optics, details of design and biomedical uses, as well as microscopic endoscopy, and endoscopic spectroscopy.



Endoscopy


Endoscopy
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Author : Costin Teodor Streba
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-03-06

Endoscopy written by Costin Teodor Streba and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-06 with Medical categories.


Endoscopic techniques are widely used for screening, diagnostic and therapeutic maneuvers in all groups of patients and for a large spectrum of complaints. The availability of basic iterations of endoscopic techniques made screening programs for various diseases viable in most parts of the world, while the advent of modern techniques opens new perspectives for rapid and correct diagnosis. Going beyond normal human vision, innovative techniques opened the prospect of in-situ pathology. Endoscopic ultrasound has made incredible progress in recent years. Reaching the smaller orifices by endoscopy was a major step forward in the surveillance of previously inaccessible lesions. Investigatory techniques were complemented by advances in therapy, with novel applications in many major areas of medicine.



Proceedings Of Optical Methods For Tumor Treatment And Early Diagnosis


Proceedings Of Optical Methods For Tumor Treatment And Early Diagnosis
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Author :
language : en
Publisher:
Release Date : 1991

Proceedings Of Optical Methods For Tumor Treatment And Early Diagnosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Cancer categories.




Optical Imaging Of Cancer


Optical Imaging Of Cancer
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Author : Eben Rosenthal
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-03

Optical Imaging Of Cancer written by Eben Rosenthal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-03 with Medical categories.


To describe principles of optical imaging including chemistry and physics of fluorescence, limitations/advantages of optical imaging compared to metabolic and anatomic imaging. Describe hardware adapted for small animal imaging and for clinical applications: endoscopes and operative microscopes. Outline FDA approved and newer optical imaging probes. Include discussion of chemistry and linkage to other proteins. Review current techniques to image cancer and the development of techniques to specifically image cancer cells. Review use of exploiting differences in tissue autofluorescence to diagnose and treat cancer. Include agents such as 5-aminoleculinic acid. Review mechanisms that require proteolytic processing within the tumor to become active fluorophores. Review use of cancer selective proteins to localize probes to cancer cells: include toxins, antibodies, and minibodies. Introduction of plasmids, viruses or other genetic material may be used to express fluorescent agents in vivo. This chapter will review multiple vectors and delivery mechanisms of optical imaging cassettes.Preclinical investigations into the use of optical contrast agents for the detection of primary tumors in conventional and orthotopic models will be discussed. Preclinical investigations into the use of optical contrast agents for the detection of metastatic tumors in mouse models will be discussed. Use of targeted and non-specific optical contrast agents have been used for the detection of sentinel lymph node detection. These applications and how they differ from other applications will be discussed. Because of the unique difficulty of identifying tumor from normal tissue in brain tissue, a separate chapter would be needed. More clinical data is available for this cancer type than any other. Discussion of potential clinical applications for optical imaging and an assessment of the potential market.



Safety In Minimal Access Surgery


Safety In Minimal Access Surgery
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Author : Om Tantia
language : en
Publisher: Jaypee Brothers Medical Publishers
Release Date : 2021-02-13

Safety In Minimal Access Surgery written by Om Tantia and has been published by Jaypee Brothers Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-13 with Medical categories.




Gastroenterology And Nutrition


Gastroenterology And Nutrition
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Author : Derek G. Waller
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-09-13

Gastroenterology And Nutrition written by Derek G. Waller and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-13 with Medical categories.


Gastroenterology & Nutrition is a new e-book in a collection of subject-themed e-books containing relevant key articles from Medicine. The e-books provide a perfect source of revision for post-graduate exams in clinical medicine and portfolio material for life-long learning. As well as mapping to the UK Core Medical Training curriculum, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. The whole board has been involved in the creation of this content and are therefore listed as authors on all the e-books. In addition we extend our warm thanks for their contribution to these e-books to the past Chairman Allister Vale (who stepped down from the board in 2015) and to John Mucklow, who stepped down in 2016. Derek Waller, on behalf of the Editorial Board About the journal The parent journal (www.medicinejournal.co.uk) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for core medical training. Its Editorial Board comprises some of Europe’s most influential specialists. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates. About the Medicine journal e-books Gastroenterology & Nutrition is a new e-book in a collection of subject-themed e-books containing relevant key articles from Medicine. The e-books provide a perfect source of revision for post-graduate exams in clinical medicine and portfolio material for life-long learning. As well as mapping to the UK Core Medical Training curriculum, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. The whole board has been involved in the creation of this content and are therefore listed as authors on all the e-books. In addition we extend our warm thanks for their contribution to these e-books to the past Chairman Allister Vale (who stepped down from the board in 2015) and to John Mucklow, who stepped down in 2016. Derek Waller, on behalf of the Editorial Board About the journal The parent journal (www.medicinejournal.co.uk) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for core medical training. Its Editorial Board comprises some of Europe’s most influential specialists. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates.