Time Lags In Biological Models

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Time Lags In Biological Models

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Author : N. MacDonald
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08

Time Lags In Biological Models written by N. MacDonald and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Mathematics categories.

In many biological models it is necessary to allow the rates of change of the variables to depend on the past history, rather than only the current values, of the variables. The models may require discrete lags, with the use of delay-differential equations, or distributed lags, with the use of integro-differential equations. In these lecture notes I discuss the reasons for including lags, especially distributed lags, in biological models. These reasons may be inherent in the system studied, or may be the result of simplifying assumptions made in the model used. I examine some of the techniques available for studying the solution of the equations. A large proportion of the material presented relates to a special method that can be applied to a particular class of distributed lags. This method uses an extended set of ordinary differential equations. I examine the local stability of equilibrium points, and the existence and frequency of periodic solutions. I discuss the qualitative effects of lags, and how these differ according to the choice of discrete or distributed lag. The models studied are drawn from the population dynamiCS of single species (logistic growth, the chemostat) and of interacting pairs of species (predation, mutualism), from cell population dynamiCS (haemopoiesis) and from biochemical kinetics (the Goodwin oscillator). The last chapter is devoted to a population model employing difference equations. All these models include non-linear terms.

Biological Delay Systems

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Author : Norman MacDonald
language : en
Publisher: Cambridge University Press
Release Date : 2008-01-03

Biological Delay Systems written by Norman MacDonald and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-03 with Mathematics categories.

In studying the dynamics of populations, whether of animals, plants or cells, it is crucial to allow for delays such as those due to gestation, maturation or transport. This book deals with a fundamental question in the analysis of the effects of delays, namely whether they affect the stability of steady states.

Optimal Control Applied To Biological Models

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Author : Suzanne Lenhart
language : en
Publisher: CRC Press
Release Date : 2007-05-07

Optimal Control Applied To Biological Models written by Suzanne Lenhart and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-07 with Mathematics categories.

From economics and business to the biological sciences to physics and engineering, professionals successfully use the powerful mathematical tool of optimal control to make management and strategy decisions. Optimal Control Applied to Biological Models thoroughly develops the mathematical aspects of optimal control theory and provides insight into t

Delay Differential Equations And Applications To Biology

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Author : Fathalla A. Rihan
language : en
Publisher: Springer Nature
Release Date : 2021-08-19

Delay Differential Equations And Applications To Biology written by Fathalla A. Rihan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-19 with Mathematics categories.

This book discusses the numerical treatment of delay differential equations and their applications in bioscience. A wide range of delay differential equations are discussed with integer and fractional-order derivatives to demonstrate their richer mathematical framework compared to differential equations without memory for the analysis of dynamical systems. The book also provides interesting applications of delay differential equations in infectious diseases, including COVID-19. It will be valuable to mathematicians and specialists associated with mathematical biology, mathematical modelling, life sciences, immunology and infectious diseases.

Dynamic Models And Control Of Biological Systems

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Author : Vadrevu Sree Hari Rao
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-07-30

Dynamic Models And Control Of Biological Systems written by Vadrevu Sree Hari Rao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-30 with Science categories.

Mathematical Biology has grown at an astonishing rate and has established itself as a distinct discipline. Mathematical modeling is now being applied in every major discipline in the biological sciences. Though the field has become increasingly large and specialized, this book remains important as a text that introduces some of the exciting problems which arise in the biological sciences and gives some indication of the wide spectrum of questions that modeling can address.

Mathematical Biology

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Author : James D. Murray
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Mathematical Biology written by James D. Murray and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Mathematics categories.

Mathematical biology - the use of mathematical ideas and models in the biosciences - is a fast growing, very exciting and increasingly important inderdisciplinary field. This textbook is an account of some of the major techniques and models used and of some genuine practical applications drawn from current areas of research interest in, for example, population ecology, developmental biology, physiology, epidemiology and evolution. It provides the reader with a thorough background, sufficient to start genuine interdisciplinary collaborative reserach with biomedical scientists.

Mathematical Modeling

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Author : Sandip Banerjee
language : en
Publisher: CRC Press
Release Date : 2021-12-05

Mathematical Modeling written by Sandip Banerjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-05 with Mathematics categories.

Mathematical Modeling: Models, Analysis and Applications, Second Edition introduces models of both discrete and continuous systems. This book is aimed at newcomers who desires to learn mathematical modeling, especially students taking a first course in the subject. Beginning with the step-by-step guidance of model formulation, this book equips the reader about modeling with difference equations (discrete models), ODE’s, PDE’s, delay and stochastic differential equations (continuous models). This book provides interdisciplinary and integrative overview of mathematical modeling, making it a complete textbook for a wide audience. A unique feature of the book is the breadth of coverage of different examples on mathematical modelling, which include population models, economic models, arms race models, combat models, learning model, alcohol dynamics model, carbon dating, drug distribution models, mechanical oscillation models, epidemic models, tumor models, traffic flow models, crime flow models, spatial models, football team performance model, breathing model, two neuron system model, zombie model and model on love affairs. Common themes such as equilibrium points, stability, phase plane analysis, bifurcations, limit cycles, period doubling and chaos run through several chapters and their interpretations in the context of the model have been highlighted. In chapter 3, a section on estimation of system parameters with real life data for model validation has also been discussed. Features Covers discrete, continuous, spatial, delayed and stochastic models. Over 250 illustrations, 300 examples and exercises with complete solutions. Incorporates MATHEMATICA® and MATLAB®, each chapter contains Mathematica and Matlab codes used to display numerical results (available at CRC website). Separate sections for Projects. Several exercise problems can also be used for projects. Presents real life examples of discrete and continuous scenarios. The book is ideal for an introductory course for undergraduate and graduate students, engineers, applied mathematicians and researchers working in various areas of natural and applied sciences.

Recent Trends In Mathematical Modeling And High Performance Computing

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Author : Vinai K. Singh
language : en
Publisher: Springer Nature
Release Date : 2021-08-23

Recent Trends In Mathematical Modeling And High Performance Computing written by Vinai K. Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-23 with Mathematics categories.

This volume explores the connections between mathematical modeling, computational methods, and high performance computing, and how recent developments in these areas can help to solve complex problems in the natural sciences and engineering. The content of the book is based on talks and papers presented at the conference Modern Mathematical Methods and High Performance Computing in Science & Technology (M3HPCST), held at Inderprastha Engineering College in Ghaziabad, India in January 2020. A wide range of both theoretical and applied topics are covered in detail, including the conceptualization of infinity, efficient domain decomposition, high capacity wireless communication, infectious disease modeling, and more. These chapters are organized around the following areas: Partial and ordinary differential equations Optimization and optimal control High performance and scientific computing Stochastic models and statistics Recent Trends in Mathematical Modeling and High Performance Computing will be of interest to researchers in both mathematics and engineering, as well as to practitioners who face complex models and extensive computations.

Ordinary Differential Equations And Integral Equations

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Author : C.T.H. Baker
language : en
Publisher: Gulf Professional Publishing
Release Date : 2001-07-04

Ordinary Differential Equations And Integral Equations written by C.T.H. Baker and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-04 with Juvenile Nonfiction categories.

/homepage/sac/cam/na2000/index.html7-Volume Set now available at special set price ! This volume contains contributions in the area of differential equations and integral equations. Many numerical methods have arisen in response to the need to solve "real-life" problems in applied mathematics, in particular problems that do not have a closed-form solution. Contributions on both initial-value problems and boundary-value problems in ordinary differential equations appear in this volume. Numerical methods for initial-value problems in ordinary differential equations fall naturally into two classes: those which use one starting value at each step (one-step methods) and those which are based on several values of the solution (multistep methods). John Butcher has supplied an expert's perspective of the development of numerical methods for ordinary differential equations in the 20th century. Rob Corless and Lawrence Shampine talk about established technology, namely software for initial-value problems using Runge-Kutta and Rosenbrock methods, with interpolants to fill in the solution between mesh-points, but the 'slant' is new - based on the question, "How should such software integrate into the current generation of Problem Solving Environments?" Natalia Borovykh and Marc Spijker study the problem of establishing upper bounds for the norm of the nth power of square matrices. The dynamical system viewpoint has been of great benefit to ODE theory and numerical methods. Related is the study of chaotic behaviour. Willy Govaerts discusses the numerical methods for the computation and continuation of equilibria and bifurcation points of equilibria of dynamical systems. Arieh Iserles and Antonella Zanna survey the construction of Runge-Kutta methods which preserve algebraic invariant functions. Valeria Antohe and Ian Gladwell present numerical experiments on solving a Hamiltonian system of Hénon and Heiles with a symplectic and a nonsymplectic method with a variety of precisions and initial conditions. Stiff differential equations first became recognized as special during the 1950s. In 1963 two seminal publications laid to the foundations for later development: Dahlquist's paper on A-stable multistep methods and Butcher's first paper on implicit Runge-Kutta methods. Ernst Hairer and Gerhard Wanner deliver a survey which retraces the discovery of the order stars as well as the principal achievements obtained by that theory. Guido Vanden Berghe, Hans De Meyer, Marnix Van Daele and Tanja Van Hecke construct exponentially fitted Runge-Kutta methods with s stages. Differential-algebraic equations arise in control, in modelling of mechanical systems and in many other fields. Jeff Cash describes a fairly recent class of formulae for the numerical solution of initial-value problems for stiff and differential-algebraic systems. Shengtai Li and Linda Petzold describe methods and software for sensitivity analysis of solutions of DAE initial-value problems. Again in the area of differential-algebraic systems, Neil Biehn, John Betts, Stephen Campbell and William Huffman present current work on mesh adaptation for DAE two-point boundary-value problems. Contrasting approaches to the question of how good an approximation is as a solution of a given equation involve (i) attempting to estimate the actual error (i.e., the difference between the true and the approximate solutions) and (ii) attempting to estimate the defect - the amount by which the approximation fails to satisfy the given equation and any side-conditions. The paper by Wayne Enright on defect control relates to carefully analyzed techniques that have been proposed both for ordinary differential equations and for delay differential equations in which an attempt is made to control an estimate of the size of the defect. Many phenomena incorporate noise, and the numerical solution of stochastic differential equations has developed as a relatively new item of study in the area. Keven Burrage, Pamela Burrage and Taketomo Mitsui review the way numerical methods for solving stochastic differential equations (SDE's) are constructed. One of the more recent areas to attract scrutiny has been the area of differential equations with after-effect (retarded, delay, or neutral delay differential equations) and in this volume we include a number of papers on evolutionary problems in this area. The paper of Genna Bocharov and Fathalla Rihan conveys the importance in mathematical biology of models using retarded differential equations. The contribution by Christopher Baker is intended to convey much of the background necessary for the application of numerical methods and includes some original results on stability and on the solution of approximating equations. Alfredo Bellen, Nicola Guglielmi and Marino Zennaro contribute to the analysis of stability of numerical solutions of nonlinear neutral differential equations. Koen Engelborghs, Tatyana Luzyanina, Dirk Roose, Neville Ford and Volker Wulf consider the numerics of bifurcation in delay differential equations. Evelyn Buckwar contributes a paper indicating the construction and analysis of a numerical strategy for stochastic delay differential equations (SDDEs). This volume contains contributions on both Volterra and Fredholm-type integral equations. Christopher Baker responded to a late challenge to craft a review of the theory of the basic numerics of Volterra integral and integro-differential equations. Simon Shaw and John Whiteman discuss Galerkin methods for a type of Volterra integral equation that arises in modelling viscoelasticity. A subclass of boundary-value problems for ordinary differential equation comprises eigenvalue problems such as Sturm-Liouville problems (SLP) and Schrödinger equations. Liviu Ixaru describes the advances made over the last three decades in the field of piecewise perturbation methods for the numerical solution of Sturm-Liouville problems in general and systems of Schrödinger equations in particular. Alan Andrew surveys the asymptotic correction method for regular Sturm-Liouville problems. Leon Greenberg and Marco Marletta survey methods for higher-order Sturm-Liouville problems. R. Moore in the 1960s first showed the feasibility of validated solutions of differential equations, that is, of computing guaranteed enclosures of solutions. Boundary integral equations. Numerical solution of integral equations associated with boundary-value problems has experienced continuing interest. Peter Junghanns and Bernd Silbermann present a selection of modern results concerning the numerical analysis of one-dimensional Cauchy singular integral equations, in particular the stability of operator sequences associated with different projection methods. Johannes Elschner and Ivan Graham summarize the most important results achieved in the last years about the numerical solution of one-dimensional integral equations of Mellin type of means of projection methods and, in particular, by collocation methods. A survey of results on quadrature methods for solving boundary integral equations is presented by Andreas Rathsfeld. Wolfgang Hackbusch and Boris Khoromski present a novel approach for a very efficient treatment of integral operators. Ernst Stephan examines multilevel methods for the h-, p- and hp- versions of the boundary element method, including pre-conditioning techniques. George Hsiao, Olaf Steinbach and Wolfgang Wendland analyze various boundary element methods employed in local discretization schemes.

Mathematical Ecology Of Populations And Ecosystems

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Author : John Pastor
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-31

Mathematical Ecology Of Populations And Ecosystems written by John Pastor and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-31 with Science categories.

MATHEMATICAL ECOLOGY Population ecologists study how births and deaths affect the dynamics of populations and communities, while ecosystem ecologists study how species control the flux of energy and materials through food webs and ecosystems. Although all these processes occur simultaneously in nature, the mathematical frameworks bridging the two disciplines have developed independently. Consequently, this independent development of theory has impeded the cross-fertilization of population and ecosystem ecology. Using recent developments from dynamical systems theory, this advanced undergraduate/graduate level textbook shows how to bridge the two disciplines seamlessly. The book shows how bifurcations between the solutions of models can help understand regime shifts in natural populations and ecosystems once thresholds in rates of births, deaths, consumption, competition, nutrient inputs, and decay are crossed. Mathematical Ecology is essential reading for students of ecology who have had a first course in calculus and linear algebra or students in mathematics wishing to learn how dynamical systems theory can be applied to ecological problems.