Tissue Specific In Vitro And In Vivo Evaluation Of Tamoxifen Medicated Gene Expression
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Tissue Specific In Vitro And In Vivo Evaluation Of Tamoxifen Medicated Gene Expression
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Author : Cora Jung-Yee Fong
language : en
Publisher:
Release Date : 2007
Tissue Specific In Vitro And In Vivo Evaluation Of Tamoxifen Medicated Gene Expression written by Cora Jung-Yee Fong and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Ethinyl estradiol categories.
Dissertation Abstracts International
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Author :
language : en
Publisher:
Release Date : 2009
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Dissertations, Academic categories.
The Nuclear Receptor Factsbook
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Author : Vincent Laudet
language : en
Publisher: Elsevier
Release Date : 2001-10-24
The Nuclear Receptor Factsbook written by Vincent Laudet and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-24 with Science categories.
The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure, Isolation, DNA binding properties, Ligands, Expression, Target genes, Knockouts, Disease association, Gene structure, promoter and isoforms, Chromosomal location, Amino acid sequences, Key references
Iarc Monographs On The Evaluation Of Carcinogenic Risks To Humans
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Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
language : en
Publisher:
Release Date : 1988
Iarc Monographs On The Evaluation Of Carcinogenic Risks To Humans written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Carcinogenesis categories.
Estrogen Receptor And Breast Cancer
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Author : Xiaoting Zhang
language : en
Publisher: Humana Press
Release Date : 2019-11-08
Estrogen Receptor And Breast Cancer written by Xiaoting Zhang and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-08 with categories.
The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.
Recapitulating The Stem Cell Niche Ex Vivo
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Author : Susie Nilsson
language : en
Publisher: Academic Press
Release Date : 2022-07-12
Recapitulating The Stem Cell Niche Ex Vivo written by Susie Nilsson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with Science categories.
Recapitulating The Stem Cell Niche Ex Vivo, Volume Six in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Recapitulating the bone marrow stem cell niche ex vivo, The generation of the liver ex vivo, Recapitulating the thymic stem cell niche ex vivo, Recapitulating the intestinal epithelium stem cell niche ex vivo, Recapitulating the lung stem cell niche in vitro, Recapitulating mammary tissue in vitro, and Recapitulating muscle in vitro. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Stem Cells and their Niches series Includes the latest information on Recapitulating the stem cell niche ex vivo
Multifaceted Development And Application Of Biopolymers For Biology Biomedicine And Nanotechnology
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Author : P.K. Dutta
language : en
Publisher: Springer
Release Date : 2013-09-18
Multifaceted Development And Application Of Biopolymers For Biology Biomedicine And Nanotechnology written by P.K. Dutta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-18 with Technology & Engineering categories.
Nanoparticles for Gene Delivery into Stem Cells and Embryos, by Pallavi Pushp, Rajdeep Kaur, Hoon Taek Lee, Mukesh Kumar Gupta. Engineering of Polysaccharides via Nanotechnology, by Joydeep Dutta. Hydroxyapatite-Packed Chitosan-PMMA Nanocomposite: A Promising Material for Construction of Synthetic Bone, by Arundhati Bhowmick, Subhash Banerjee, Ratnesh Kumar, Patit Paban Kundu. Biodegradable Polymers for Potential Delivery Systems for Therapeutics, by Sanjeev K. Pandey, Chandana Haldar, Dinesh K. Patel, Pralay Maiti. Phytomedicine-Loaded Polymeric Nanomedicines: Potential Cancer Therapeutics, by S. Maya, M. Sabitha, Shantikumar V. Nair, R. Jayakumar. Proteins and Carbohydrates as Polymeric Nanodrug Delivery Systems: Formulation, Properties and Toxicological Evaluation, by Dhanya Narayanan, J. Gopikrishna, Shantikumar V. Nair, Deepthy Menon. Biopolymeric Micro and Nanoparticles: Preparation, Characterization and Industrial Applications, by Anil Kumar Anal, Alisha Tuladhar. Applications of Glyconanoparticles as “Sweet” Glycobiological Therapeutics and Diagnostics, by Naresh Kottari, Yoann M. Chabre, Rishi Sharma, René Roy.
Journal Of The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 2009
Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Cancer categories.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 2000
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medicine categories.
Gene Knockout Protocols
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Author : Ralf Kühn
language : en
Publisher: Humana Press
Release Date : 2009-03-27
Gene Knockout Protocols written by Ralf Kühn and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-27 with Science categories.
Following the completion of the mouse and human genome sequences, a major challengeisthefunctionalcharacterizationofeverymammaliangeneandthedeciph- ing of their molecular interaction network. The mouse offers many advantages for the use of genetics to study human biology and disease, unmatched among other m- mals. Its development, body plan, physiology, behavior, and diseases have much in common, based on the fact that 99% of the human genes have a mouse ortholog. The investigation of gene function using mouse models is based on many years of tech- logical development. In the two decades since gene targeting in murine embryonic stem (ES) cells was first described by Mario Capecchi and colleagues, more than 3000 predesigned mouse mutants have been developed. To date, a variety of mouse mutagenesis techniques, either gene- or phenotype-driven, are used as systematic approaches. The availability of the genome sequence supports gene-driven approaches such as gene-trap and targeted mutagenesis in ES cells, allowing efficient and precise gene disruption. In combination with the use of site-specific DNA recombinases, in particular the Cre/loxP system, gene disruptioncan be directed to specific cell types in conditionalmousemutants. Furthermore,chemicalandtransposonmutagenesisofthe mouse genome enables us to perform phenotype-driven screens for the unbiased identification of phenotype–genotype correlations involved in models of human d- ease. Over the next several years, the mouse genome will be systematically altered, and the techniques for achieving predesigned manipulations will be constantly developed further and improved. The second edition of Gene Knockout Protocols brings together distinguished c- tributorswithextensiveexperienceinthegenetargetingandmousegeneticsfields.