Toxicological Risk Assessment For Beginners
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Toxicological Risk Assessment For Beginners
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Author : José A. Torres
language : en
Publisher: Springer
Release Date : 2015-03-27
Toxicological Risk Assessment For Beginners written by José A. Torres and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-27 with Medical categories.
This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypothetical case studies. Toxicological Risk Assessment for Beginners aims not to create an expert, but rather to provide readers with their first understanding of the risk assessment topic. This book was designed with the student in mind. We simplify a complex process for beginners and balance theory with practical aspects, but remain fluid enough to increase difficulty with case studies. By incorporating an action based, step by step approach to learning the risk assessment process, this book provides its readers with an elementary understanding of how the risk assessment process is initiated, developed and finished, making it a valuable guide for graduate students, post-doctoral fellows and early career scientists in industry.
A Practical Guide To Toxicology And Human Health Risk Assessment
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Author : Laura Robinson
language : en
Publisher: John Wiley & Sons
Release Date : 2018-11-05
A Practical Guide To Toxicology And Human Health Risk Assessment written by Laura Robinson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-05 with Science categories.
Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.
Toxicological Risk Assessment And Multi System Health Impacts From Exposure
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Author : Aristidis M. Tsatsakis
language : en
Publisher: Elsevier
Release Date : 2021-08-05
Toxicological Risk Assessment And Multi System Health Impacts From Exposure written by Aristidis M. Tsatsakis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-05 with Medical categories.
Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research
Environmental Risk Assessment
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Author : Ted Simon
language : en
Publisher: CRC Press
Release Date : 2019-12-06
Environmental Risk Assessment written by Ted Simon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-06 with Medical categories.
The purpose of risk assessment is to support science-based decisions about how to solve complex societal problems. Indeed, the problems humankind faces in the 21st century have many social, political, and technical complexities. Environmental risk assessment in particular is of increasing importance as health and safety regulations grow and become more complicated. Environmental Risk Assessment: A Toxicological Approach, 2nd Edition looks at various factors relating to exposure and toxicity, human health, and risk. In addition to the original chapters being updated and expanded upon, four new chapters discuss current software and platforms that have recently been developed and provide examples of risk characterizations and scenarios. Features: Introduces the science of risk assessment—past, present, and future Provides environmental sampling data for conducting practice risk assessments Considers how bias and conflict of interest affect science-based decisions in the 21st century Includes fully worked examples, case studies, discussion questions, and suggestions for additional reading Discusses new software and computational platforms that have developed since the first edition Aimed at the next generation of risk assessors and students who need to know more about developing, conducting, and interpreting risk assessments, the book delivers a comprehensive view of the field, complete with sufficient background to enable readers to probe for themselves the science underlying the key issues in environmental risk.
Practical Toxicology
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Author : David Woolley
language : en
Publisher: CRC Press
Release Date : 2017-03-16
Practical Toxicology written by David Woolley and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-16 with Medical categories.
Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data. Revised and updated chapters on risk assessment guide the reader to setting the foundations necessary for submission to regulatory authorities. In addition, a new chapter in the book reviews the errors in toxicology, mistakes, misuse, mismanagement, and misunderstanding with a view to avoiding these in the future. New Chapters in the Third Edition: Toxicology in silico Errors in Toxicology Safety Assessment of Extractables and Leachables. This new edition follows a practical sequence from introducing the basics of toxicology (including the vital concept of normality in controls) to describing a test program and then interpreting the data and translating that to risk assessment that can be used in a number of real world situations where safety and secure risk assessment are essential. Although written primarily from the perspective of pharmaceutical development, the test designs and toxicological problems encountered in that field are entirely relevant to those with other classes of chemicals, the only difference being the regulatory context. Toxicology is an international discipline and the book has been written to take into account some of the differences in regulatory nuance between the main regions of the world. Completely revised and written in an easily accessible style, the text address several audiences—from students and post-graduates coming to the subject for the first time to established professionals who find themselves needing to learn about toxicology, toxicity testing, interpretation of the results, and risk assessment. It is intended primarily as a textbook, with case studies and information on where to go to ask questions, but can also be used as a practical reference book. It covers all the basics of toxicology and the main aspects of safety evaluation testing and risk assessment while reviewing critically the current state of the discipline. It also provides a foundation for those seeking registration or certification.
Oxford Textbook Of Global Public Health
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Author : Roger Detels
language : en
Publisher: Oxford University Press
Release Date : 2017
Oxford Textbook Of Global Public Health written by Roger Detels and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Medical categories.
Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology comprehensively covering the scope, methods, and practice of the discipline.
Risk Assessment Of Chemicals An Introduction
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Author : C.J. van Leeuwen
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-18
Risk Assessment Of Chemicals An Introduction written by C.J. van Leeuwen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-18 with Science categories.
At last – a second edition of this hugely important text that reflects the progress and experience gained in the last decade and aims at providing background and training material for a new generation of risk assessors. The authors offer an introduction to risk assessment of chemicals as well as basic background information on sources, emissions, distribution and fate processes for the estimation of exposure of plant and animal species in the environment and humans exposed via the environment, consumer products, and at the workplace. The coverage describes the basic principles and methods of risk assessment within their legislative frameworks (EU, USA, Japan and Canada).
Exposure And Risk Assessment Of Chemical Pollution Contemporary Methodology
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Author : Mahmoud A. Hassanien
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-31
Exposure And Risk Assessment Of Chemical Pollution Contemporary Methodology written by Mahmoud A. Hassanien and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-31 with Science categories.
The book contains the contributions at the NATO Study Institute on Exposure and Risk Assessment of Chemical Pollution – Contemporary Methodology, which took place in Sofia – Borovetz, Bulgaria, July 1–10, 2008. Rapid advances in mathematics, computer science and molecular biology and chemistry have lead to the development in of a new branch of toxicology called Computational Toxicology. This emerging field is addressing the estimation and prediction of exposure risk and effects of chemicals based on experimental data, measured concentration and biological mechanisms and computational models of biological systems. Mathematical models are also being used to predict the fate and transport of substances in the environment. Because this area is still in its infancy, there has been limited application from governmental agencies to regulating controllable processes, such as registration of new chemicals, determination of estimated exposure and risk based limits and maximum acceptable concentrations in different compartments of the environment – ambient air, waters, soil and food products. However, this is soon to change as the ability to collect, analyze and interpret the required information is becoming increasingly more efficient and cost effective. Full implementation of the new processes have to involve education on both part of the experimentalists who are generating the data and the models, and the risk assessors who will use them to better protect human health and the environment.
Risk Assessment Methods
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Author : V.T. Covello
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Risk Assessment Methods written by V.T. Covello and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Technology & Engineering categories.
Much has already been written about risk assessment. Epidemiologists write books on how risk assessment is used to explore the factors that influence the distribution of disease in populations of people. Toxicologists write books on how risk assess ment involves exposing animals to risk agents and concluding from the results what risks people might experience if similarly exposed. Engineers write books on how risk assessment is utilized to estimate the risks of constructing a new facility such as a nuclear power plant. Statisticians write books on how risk assessment may be used to analyze mortality or accident data to determine risks. There are already many books on risk assessment-the trouble is that they all seem to be about different sUbjects! This book takes another approach. It brings together all the methods for assessing risk into a common framework, thus demonstrating how the various methods relate to one another. This produces four important benefits: • First, it provides a comprehensive reference for risk assessment. This one source offers readers concise explanations of the many methods currently available for describing and quantifying diverse types of risks. • Second, it consistently evaluates and compares available risk assessment methods and identifies their specific strengths and limitations. Understand ing the limitations of risk assessment methods is important. The field is still in its infancy, and the problems with available methods are disappoint ingly numerous. At the same time, risk assessment is being used.
Toxicological Risk Assessment Of Chemicals
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Author : Elsa Nielsen
language : en
Publisher: CRC Press
Release Date : 2008-02-21
Toxicological Risk Assessment Of Chemicals written by Elsa Nielsen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-21 with Medical categories.
Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk