Toxins And Cancer Therapy
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Toxins And Cancer Therapy
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Author : Adam E. Snook
language : en
Publisher: MDPI
Release Date : 2021-03-02
Toxins And Cancer Therapy written by Adam E. Snook and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-02 with Science categories.
Cancer has been a patient-specific and difficult-to-treat disease for decades, resulting in more deaths since 1900 than all other diseases except cardiovascular diseases. As societies around the world continue to shift towards an aging population, the social and economic burden created by cancer will only rise in the coming decades, necessitating continued improvement in our cancer therapies. Remarkably, in the late 1800s, bone surgeon William Coley serendipitously discovered that bacteria could be administered to patients as an effective (and sometimes toxic) form of cancer therapy known as "Coley's Toxins". His discoveries unknowingly led to two fields of cancer therapy that have been in development for decades and are now leading to significant improvements in therapy for cancer patients: immune-based and toxin-based therapies for cancer. Articles included here discuss the discoveries that emerged from Coley's Toxins that enable us to harness the immune system and microbial toxins to combat cancers, as oncology shifts from a field dominated by chemotherapy for most of the 20th century to biologic therapies that will dominate the 21st century.
Toxins And Cancer Therapy
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Author : Adam E. Snook
language : en
Publisher:
Release Date : 2021
Toxins And Cancer Therapy written by Adam E. Snook and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Cancer has been a patient-specific and difficult-to-treat disease for decades, resulting in more deaths since 1900 than all other diseases except cardiovascular diseases. As societies around the world continue to shift towards an aging population, the social and economic burden created by cancer will only rise in the coming decades, necessitating continued improvement in our cancer therapies. Remarkably, in the late 1800s, bone surgeon William Coley serendipitously discovered that bacteria could be administered to patients as an effective (and sometimes toxic) form of cancer therapy known as "Coley's Toxins". His discoveries unknowingly led to two fields of cancer therapy that have been in development for decades and are now leading to significant improvements in therapy for cancer patients: immune-based and toxin-based therapies for cancer. Articles included here discuss the discoveries that emerged from Coley's Toxins that enable us to harness the immune system and microbial toxins to combat cancers, as oncology shifts from a field dominated by chemotherapy for most of the 20th century to biologic therapies that will dominate the 21st century.
Cancer Therapy
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Author : Ralph W. Moss
language : en
Publisher:
Release Date : 1992
Cancer Therapy written by Ralph W. Moss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Health & Fitness categories.
This thorough guide is a must-read for cancer patients and their families seeking treatment options.
Venom And Toxin As Targeted Therapy
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Author : Hang Fai (Henry) Kwok
language : en
Publisher: MDPI
Release Date : 2019-10-01
Venom And Toxin As Targeted Therapy written by Hang Fai (Henry) Kwok and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-01 with Science categories.
Targeted therapy has developed significantly in the last one and half decades, prescribing specific medications for treatment of particular diseases, such as cancer, diabetes, and heart disease. One of the most exciting recent developments in targeted therapies was the isolation of disease-specific molecules from natural resources, such as animal venoms and plant metabolites/toxins, for use as templates for new drug motif designs. In addition, the study of venom proteins/peptides and toxins naturally targeted mammalian receptors and demonstrated high specificity and selectivity towards defined ion channels of cell membranes. Research has also focsed intensely on receptors. The focus of this Special Issue of Toxins addressed the most recent advances using animal venoms, such as frog secretions, bee/ant venoms and plant/fungi toxins, as medicinal therapy. Recent advances in venom/toxin/immunotoxins for targeted cancer therapy and immunotherapy, along with using novel disease-specific venom-based protein/peptide/toxin and currently available FDA-approved drugs for combinationtreatments will be discussed. Finally, we included an overview of select promising toad/snake venom-based peptides/toxins potentially able to address the forthcoming challenges in this field. Both research and review articles proposing novelties or overviews, respectively, were published in this Special Issue after rigorous evaluation and revision by expert peer reviewers.
Strategies To Mitigate The Toxicity Of Cancer Therapeutics
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-06-30
Strategies To Mitigate The Toxicity Of Cancer Therapeutics written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-30 with Medical categories.
Strategies to Mitigate the Toxicity of Cancer Therapeutics, Volume 155 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters, each of which is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Cancer Research series Includes the latest information on Strategies to Mitigate the Toxicity of Cancer Therapeutics
Cytotoxins And Immunotoxins For Cancer Therapy
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Author : Koji Kawakami
language : en
Publisher: CRC Press
Release Date : 2004-11-15
Cytotoxins And Immunotoxins For Cancer Therapy written by Koji Kawakami and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-15 with Medical categories.
Recent advances in cytotoxins and immunotoxins are accelerating our understanding of cancer and leading to more effective therapeutic treatments. Although a large number of articles have been published on these cytotoxins and immunotoxins, this important information has yet to be compiled into one comprehensive resource. For the first time,
Immunotoxins
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Author : Arthur E. Frankel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunotoxins written by Arthur E. Frankel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Chimeric Toxins
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Author : Haya Lorberboum-Galski
language : en
Publisher: CRC Press
Release Date : 2002-05-30
Chimeric Toxins written by Haya Lorberboum-Galski and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-05-30 with Medical categories.
Bacteria and plants produce powerful toxins that can cause a variety of diseases, some of which are lethal for many animal species. The mechanisms of action are common to many of these toxins and represent general pathways for the interaction of a number of biomolecules with target cells, such as binding to specific surface receptors, internalizati
Treatment Of Bone And Soft Tissue Sarcomas
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Author : Per-Ulf Tunn
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-28
Treatment Of Bone And Soft Tissue Sarcomas written by Per-Ulf Tunn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-28 with Medical categories.
Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.
Resistance To Immunotoxins In Cancer Therapy
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Author : Rama Shanker Verma
language : en
Publisher:
Release Date : 2015
Resistance To Immunotoxins In Cancer Therapy written by Rama Shanker Verma and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
This volume is a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance. Each chapter discusses different aspects of resistance and covers all the factors that may contribute to resistance in cancer cells. Finally, this volume highlights the recent findings and advances associated with tackling cancer resistance.