Translational Research Methods In Neurodevelopmental Disorders
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Translational Research Methods In Neurodevelopmental Disorders
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Author : Stéphane Martin
language : en
Publisher: Springer Nature
Release Date : 2022-09-29
Translational Research Methods In Neurodevelopmental Disorders written by Stéphane Martin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-29 with Medical categories.
This volume explores the latest techniques used to study neurodevelopmental diseases (NDD) that range from molecular aspects to integrated research approaches and brain imaging in living rodents. Chapters in this book cover topics such as protocols to deliver shRNA in vitro and in vivo using lentiviral particles to knock-down specific protein expression; experimental procedures to use recombinant fluorescent probes to visualize endogenous proteins at the mammalian synapse; CRISPR/Cas9 toolkit to assess either gain- or loss-of-gene function in brain organoids; detailed protocols to use in vivo manipulations to correct the behavioral phenotypes in cognitive disorder mouse lines; and experimental approaches to genetically engineer macaque models of NDDs and investigate how genetic predisposition may cause neural and functional alterations. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Research Methods in Neurodevelopmental Disorders is a valuable resource for all researchers who want to learn more about this important and developing field.
Neurodevelopmental Disorders
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Author : Jo Van Herwegen
language : en
Publisher: Psychology Press
Release Date : 2014-12-05
Neurodevelopmental Disorders written by Jo Van Herwegen and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-05 with Psychology categories.
Interest in the field of neurodevelopmental disorders has grown exponentially in recent years across a range of disciplines, including psychology, psychiatry, education and neuroscience. The research itself has become more sophisticated, using multidisciplinary methods to probe interdisciplinary questions. Neurodevelopmental Disorders: Research Challenges and Solutions provides a thorough overview of the key issues involved in researching neurodevelopmental disorders. The volume includes 14 chapters, arranged over three sections. Chapters in the first section address general research challenges for the study of neurodevelopmental disorders. The second section draws upon specific disorders (such as Williams syndrome, Autism Spectrum Disorders, Down Syndrome, Fragile X Syndrome, ADHD, and Language Disorders) to consider the syndrome-specific issues or challenges that may be crucial to advancing our understanding of aspects of cognition and behavior associated with them. The final section considers how research evidence may be translated into practice to begin making an impact upon the lives of individuals who have neurodevelopmental disorders and their families. Each chapter in the book also includes ‘practical tips’ for either conducting research with individuals who have neurodevelopmental disorders or considering wider practical issues. The book will be indispensable reading for advanced students, researchers, and practitioners in the fields of developmental psychology, developmental psychopathology, special needs education, neuropsychology, and neurodevelopmental disorders.
The Oxford Handbook Of Adult Cognitive Disorders
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Author : Michael L. Alosco
language : en
Publisher: Oxford University Press
Release Date : 2019-05-07
The Oxford Handbook Of Adult Cognitive Disorders written by Michael L. Alosco and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-07 with Psychology categories.
The prevalence of adult cognitive disorders will dramatically rise over the next 25 years due to the aging population. Clinical research on adult cognitive disorders has rapidly evolved, including evidence of new adult cognitive disorders and greater insight into the clinical presentation, mechanism, diagnosis, and treatment of established diseases. The Oxford Handbook of Adult Cognitive Disorders is an up-to-date, scholarly, and comprehensive volume covering most diseases, conditions, and injuries resulting in impairments in cognitive function in adults. Topics covered include normal cognitive and brain aging, the impact of medical disorders and psychiatric illnesses on cognitive function, adult neurodevelopmental disorders, and various neurological conditions. This Handbook also provides a section on unique perspectives and special considerations for clinicians and clinical researchers, covering topics such as cognitive reserve, genetics, diversity, and neuroethics. Readers will be able to draw upon this volume to facilitate clinical practice (including differential diagnosis, treatment recommendations, assessment practices), and to obtain an in-depth review of current research across a wide spectrum of disorders, provided by leaders in their fields. The Oxford Handbook of Adult Cognitive Disorders is a one-of a kind resource appropriate for both clinicians and clinical researchers, from advanced trainees to seasoned professionals.
Meeting The Challenge Of Translational Research In Child Psychology Volume 35
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Author : Dante Cicchetti
language : en
Publisher: John Wiley & Sons
Release Date : 2009-02-03
Meeting The Challenge Of Translational Research In Child Psychology Volume 35 written by Dante Cicchetti and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-03 with Psychology categories.
The collected papers from this symposia provide scholars, students, and practitioners with access to the newest work of top tier scientists in psychology. Volume 35 addresses issues relevant to disorders of development and presents their processes and findings. It covers the translation of research on learning, attention/attention deficit, and early conduct problems into practice at a clinical and policy level. In addition, it explores cutting-edge issues in the field, heralding critical up-and-coming areas of scholarship. Academic researchers in developmental psychology, as well as developmental psychopathology will look forward to this volume.
Translational Neuroscience
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Author : James Elmer Barrett
language : en
Publisher: Cambridge University Press
Release Date : 2012-06-28
Translational Neuroscience written by James Elmer Barrett and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-28 with Medical categories.
Translational neuroscience is at the heart of clinical advancement in the fields of psychiatry, neurology and neurodevelopmental disorders. Written and edited by leading scientists and clinicians, this is a comprehensive and authoritative analysis of this emerging strategy for developing more effective treatments for brain disorders. Introductory chapters bring together perspectives from both academia and industry, while subsequent sections focus on disease groups, including bipolar disorder and depression, attention deficit hyperactivity disorder, substance abuse, autism, Alzheimer's disease, pain, epilepsy, Parkinson's disease and multiple sclerosis. Each section includes topical introductory and summary chapters, providing an overview and synthesis of the field. Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders is an important text for clinicians, scientists and students in academic settings, government agencies and industry, as well as those working in the fields of public health and the behavioural sciences.
Translational Research Models And Methods For Mother Infant Interactions And Developmental Studies
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Author : Josephine Johns
language : en
Publisher: Frontiers Media SA
Release Date : 2012-10-01
Translational Research Models And Methods For Mother Infant Interactions And Developmental Studies written by Josephine Johns and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-01 with categories.
The disruption of mother-infant interactions can have life-long detrimental consequences for offspring and mothers. This topic of Frontiers will focus on maternal-infant interactions including factors that may affect or alter infant or child development and maternal response capability in clinical and preclinical (animal) populations. Articles may highlight topics such as drug abuse, maternal neglect, altered reward systems, stress, biological and neural system development, child and infant behavioral development, genetics/epigenetics and intergenerational studies. Submissions can include research methods papers, reviews, original research articles, techniques and opinion articles that address the topics of interest. This Research Topic will highlight translational research including common measures and results found in both animal and human studies. Please contact one of the Editors for submission proposals or for additional information.
Biomarkers To Enable Therapeutics Development In Neurodevelopmental Disorders
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Author : Mustafa Sahin
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-31
Biomarkers To Enable Therapeutics Development In Neurodevelopmental Disorders written by Mustafa Sahin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-31 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Emerging Trends In The Diagnosis And Intervention Of Neurodevelopmental Disorders
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Author : Gupta, Sanjeev Kumar
language : en
Publisher: IGI Global
Release Date : 2018-10-26
Emerging Trends In The Diagnosis And Intervention Of Neurodevelopmental Disorders written by Gupta, Sanjeev Kumar and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-26 with Medical categories.
Neurodevelopmental disorders encompass a group of conditions that can typically manifest during early childhood. These include intellectual disabilities, communication disorders, autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), specific learning disorder (SLD), and motor disorders. Early identification and assessment can be a valuable tool in determining diagnosis, prognosis, functional abilities, and formulating clinical intervention for both children and adults with neurodevelopmental disorders. Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders is an essential reference source that discusses and disseminates contributions covering recent trends in diagnosis, assessment, and intervention techniques. Featuring research on topics such as clinical linguistics, neural connectivity, and animal-assisted therapy, this book is ideally designed for speech pathologists, social workers, occupational therapists, psychologists, psychiatrists, neurologists, pediatricians, researchers, clinicians, and academicians seeking coverage on neural and developmental disorder identification and strategies for clinician support and therapies.
Translational And Clinical Research In Autism Spectrum Disorders
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Author : Paul Spencer
language : en
Publisher: American Medical Publishers
Release Date : 2023-09-26
Translational And Clinical Research In Autism Spectrum Disorders written by Paul Spencer and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Medical categories.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects how a person perceives and interacts with others, leading to problems in social interaction and communication. Limited and repetitive patterns of conduct are also part of the disorder. While autism is a lifelong disease, the extent to which these challenges limit a person's capacity to function varies from person to person. The term 'spectrum disorders' signifies the wide variety of symptoms and severity associated with autism. Genetic factors are primarily the reason for the disorder's occurrence. ASD appears early in childhood and is related to social, scholastic, and occupational challenges. Autism signs appear as early as the first year of life. Some of the complications linked with the disease include difficulties in school and successful learning, work issues, inability to live independently, social isolation, and family stress. This book is a collection of translational and clinical researches on autism. The readers would gain knowledge that would broaden their perspective about autism spectrum disorders.
The Genetics Of Neurodevelopmental Disorders
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Author : Kevin J. Mitchell
language : en
Publisher: John Wiley & Sons
Release Date : 2015-08-04
The Genetics Of Neurodevelopmental Disorders written by Kevin J. Mitchell and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-04 with Medical categories.
Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.