Trends In Neuroimmunology Cross Talk Between Brain Resident And Peripheral Immune Cells In Both Health And Disease
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Trends In Neuroimmunology Cross Talk Between Brain Resident And Peripheral Immune Cells In Both Health And Disease
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Author : Estela Maris Muñoz
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-26
Trends In Neuroimmunology Cross Talk Between Brain Resident And Peripheral Immune Cells In Both Health And Disease written by Estela Maris Muñoz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-26 with Medical categories.
The functional anatomy of organisms is maintained by the coordination of different systems, that often rely on particular interactions between specialized cells and between macromolecules. The immune system works with the circulatory and the lymphatic systems to protect most of the organs. However, some organs are considered immune privileged due to the presence of highly selective and regulated barriers, such as the blood-brain barrier (BBB) within the brain. The BBB controls periphery-brain molecule exchange and prevents immune effector cells from entering the homeostatic brain. BBB-associated elements, such as endothelial cells, pericytes, astrocytes, and microglia, potentially can function as antigen-presenting cells (APC). Pathological scenarios that induce dysfunction of the BBB and its associated cells may lead to the infiltration of lymphocytes crossing over from the blood to brain. Similarly, traumas can also enable B and T lymphocytes to pass bidirectionally between the CNS and the periphery, via the meningeal lymphatic vessels which drain into the cervical lymph nodes. Research in animals and in humans has revealed that B and T cells are involved in the progression of neurological diseases. It has been showed that under particular conditions, T cells establish themselves and become resident in the brain (T RM cells), from where they can either exert beneficial or detrimental effects on brain function. Amazing efforts have been made to further comprehend interactions between brain-specific cells and peripheral immune cells, and especially their roles and impact on the onset, progression, and eventual resolution of diverse brain pathologies.
Neuroscience In The 21st Century
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Author : Donald W. Pfaff
language : en
Publisher: Springer
Release Date : 2016-10-27
Neuroscience In The 21st Century written by Donald W. Pfaff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-27 with Medical categories.
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.
Cytokines And The Cns
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Author : Richard M. Ransohoff
language : en
Publisher: CRC Press
Release Date : 2005-10-31
Cytokines And The Cns written by Richard M. Ransohoff and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-31 with Medical categories.
Provides Insight into How Cytokine Action Impacts the Physiology and Pathology of the CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised edition introduces neurobiologists to cytokine biology and immunologists to the unique functions of cytokines in CNS physiology. The dramatically accelera
Infections Of The Nervous System
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Author : David Schlossberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Infections Of The Nervous System written by David Schlossberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Dr. David Schlossberg presents his fifth volume in the series Clinical Topics in Infectious Disease, Infections of the Nervous System. This edited monograph brings together the leading authorities in infectious disease, neurology, and radiology to review the diagnosis and treatment of all major neurological infections. Topics covered include meningitis; acute CNS inflammation; infections of CNS shunts; brain and spinal epidural abscesses; the cerebellum and CNS infection; post-infection complications and syndromes; acute viral encephalitis; neurodegenerative peripheral nerve diseases; myelitis; CNS tuberculosis; cryptococcal, fungal, and parasitic infections; neurosyphilis, AIDS; Lyme disease; diagnostic imaging of CNS infection and inflammation; and evaluation of spinal fluid.
Brain Neurotrauma
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Author : Firas H. Kobeissy
language : en
Publisher: CRC Press
Release Date : 2015-02-25
Brain Neurotrauma written by Firas H. Kobeissy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-25 with Medical categories.
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
The Enteric Nervous System
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Author : John Barton Furness
language : en
Publisher:
Release Date : 1987
The Enteric Nervous System written by John Barton Furness and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
The Mouse Nervous System
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Author : Charles Watson
language : en
Publisher: Academic Press
Release Date : 2011-11-28
The Mouse Nervous System written by Charles Watson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-28 with Science categories.
The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness
Adverse Effects Of Vaccines
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-04-26
Adverse Effects Of Vaccines written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-26 with Medical categories.
In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
Prebiotics And Probiotics
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-03-04
Prebiotics And Probiotics written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-04 with Technology & Engineering categories.
Probiotic bacteria are found in the intestinal microbiota of the host and favor multiple metabolic reactions. Prebiotics provide food for probiotic bacteria and have an effect on their own performance in favor of host health. Numerous metabolic and immunological mechanisms are involved in its effects. Probiotics have been studied for several decades and their use for human consumption is still unclear. However, new types of molecules with prebiotic functions and components of probiotic bacteria with therapeutic potential are still being studied. The versatility of these molecules makes their incorporation into human food and animal diets feasible. This book is a compendium of recent scientific information on the use of probiotics and prebiotics for the benefit of human and animal health.
Philosophy Of Immunology
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Author : Thomas Pradeu
language : en
Publisher: Cambridge University Press
Release Date : 2020-02-13
Philosophy Of Immunology written by Thomas Pradeu and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-13 with Science categories.
Immunology is central to contemporary biology and medicine, but it also provides novel philosophical insights. Its most significant contribution to philosophy concerns the understanding of biological individuality: what a biological individual is, what makes it unique, how its boundaries are established and what ensures its identity through time. Immunology also offers answers to some of the most interesting philosophical questions. What is the definition of life? How are bodily systems delineated? How do the mind and the body interact? In this Element, Thomas Pradeu considers the ways in which immunology can shed light on these and other important philosophical issues. This title is also available as Open Access on Cambridge Core.