Tumor Bone Diseases And Osteoporosis In Cancer Patients
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Tumor Bone Diseases And Osteoporosis In Cancer Patients
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Author : Jean-Jac Body
language : en
Publisher: CRC Press
Release Date : 1999-10-22
Tumor Bone Diseases And Osteoporosis In Cancer Patients written by Jean-Jac Body and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-10-22 with Medical categories.
With bone metastases found to develop in more than half of patients with advanced cancers, this remarkable reference sheds much-needed light on the relation of various cancers-particularly breast and prostate cancer and multiple myeloma-to bone morbidity. The book addresses new therapies that can reduce the frequency of morbid skeletal events by as much as half. Examines cancer's effects on bone tissue from pathophysiological, diagnostic, monitoring, and therapeutic points of view! Written by more than 40 international experts in the field, Tumor Bone Diseases and Osteoporosis in Cancer Patients reviews the basics of bone physiology investigates the propensity of breast cancer cells to metastasize in bone due primarily to the abundance of growth factors in the skeletal microenvironment-strongly supporting the seed-and-soil hypothesis of the metastatic process discusses the efficacy of local radiotherapy and radioactive isotopes in treating bone metastases covers endocrine and chemotherapy trials on patients with bone metastases explores osteoclast activation and direct osteolytic effects of metastatic cancer cells evaluates the noncytotoxic treatments of bisphosphonates as potent inhibitors of osteoclast-mediated bone resorption assesses bisphosphonates as agents for ameliorating pain and preventing metastases in cancer patients describes preventive therapy against osteoporosis and more! Containing over 1700 references and more than 200 tables, drawings, and micrographs, Tumor Bone Diseases and Osteoporosis in Cancer Patients is a first-rank resource for medical, surgical, and clinical oncologists and radiotherapists, endocrinologists, internists, biologists, biochemists, and graduate and medical school students in these disciplines.
Textbook Of Bone Metastases
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Author : Claude Jasmin
language : en
Publisher: John Wiley & Sons
Release Date : 2005-09-27
Textbook Of Bone Metastases written by Claude Jasmin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-27 with Medical categories.
The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life. Bone metastases have generally received insufficient attention because of the difficulty in quantifying them, which has left them outside the scope of therapeutic trials This textbook is the result of the remarkable progress made in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis, and their development for therapeutic purposes. The treatment of malignant hypercalcaemia has also been revolutionised by the use of bisphosphonates. The Textbook of Bone Metastases presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the physiopathology of bone metastases and therapeutics. It provides a better understanding of recent advances and, more importantly, will give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases.
Metastatic Bone Disease
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Author : Ingo J. Diel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Metastatic Bone Disease written by Ingo J. Diel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
"Metastatic Bone Disease: Fundamental and Clinical Aspects" is an expanded version of a workshop on bone metastases which was held in Heidelberg, Germany, in April 1993. Bone metastases very often develop from malignant tumors and lead to complications which considerably diminish the quality of life of the patient. Bone pain, pathological fractures, and hypercalcemic syndrome should be recognized and treated ear- ly, so as to prevent any further morbidity and immobilizati- on. Antiosteolytic substances such as biophosphonate can supplement the established palliative and supportive thera- pies. Highly qualified basic researchers and clinicians in pathophysiology, diagnosis, and treatment of metastatic bone disease have contributed to this book, providing a good overview ofpresent knowledge and research. The book will be of interest not only to specialists, but also to any physi- cian interested in oncology.
Metastatic Bone Disease
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Author : R. Lor Randall
language : en
Publisher: Springer Nature
Release Date :
Metastatic Bone Disease written by R. Lor Randall and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Bone Metastases
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Author : Vassilios Vassiliou
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-19
Bone Metastases written by Vassilios Vassiliou and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-19 with Medical categories.
The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.
Handbook Of Cancer Related Bone Disease
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Author : Ralph Edward Coleman
language : en
Publisher:
Release Date : 2010
Handbook Of Cancer Related Bone Disease written by Ralph Edward Coleman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Bone metastasis categories.
Bone Metastases
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Author : Robert D. Rubens
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Bone Metastases written by Robert D. Rubens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Bone Metastases brings together the many recent developments that are gradually improving the prospects for patients with secondary involvement of the skeleton in a primary cancer elsewhere. The morbidity from bone metastases is extensive, and the palliative and supportive treatment that sufferers require for many months or even years constitutes a major health problem. A multidisciplinary approach is essential since a variety of specialists are involved: radiation and medical oncologists, general and orthopaedic surgeons, general physicians, radiologists and nuclear medicine physicians, symptom control and terminal care specialists. The book's editors, themselves authorities in the fields of oncology and bone disease respectively, have brought together experts from all these disciplines to provide comprehensive coverage of metastatic bone disease. They cover the biology and pathophysiology, hypercalcaemia, imaging, assessment of response to treatment, types of treatment (systemic, radiotherapy, surgery), and symptomatic and supportive care. Particularly new approaches included are magnetic resonance imaging, the assessment of skeletal response and isotope therapy.
Bone Remodelling And Its Disorders
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Author : Gregory R Mundy
language : en
Publisher: CRC Press
Release Date : 1999-01-01
Bone Remodelling And Its Disorders written by Gregory R Mundy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-01 with Medical categories.
Abnormalities in bone remodelling occur in some of the most common diseases, including osteoporosis, cancer and Paget's disease, and cause considerable suffering This book bridges the gap between cellular and molecular biology, and pathophysiology and treatment This practical and succinct text will be of interest for all those involved in the study, diagnosis and treatment of bone disease
Bone And Cancer
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Author : Felix Bronner
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-20
Bone And Cancer written by Felix Bronner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-20 with Medical categories.
The fifth in a series of reviews, centered on a single major topic (vol. 1 Bone Formation, vol. 2 Bone Resorption, vol. 3 Engineering of Functional Skeletal Tissues, vol. 4 Osteoarthritis) written by acknowledged authorities in the field, and aimed at researchers, clinicians and others involved in the bone field.
Bone Mineral Metabolism In Cancer
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Author : J. Szymendera
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Bone Mineral Metabolism In Cancer written by J. Szymendera and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The introduction of new methods for studying the plasma state, renal handling, and kinetics of calcium and inorganic phosphate has rendered possible a more efficient and appropriate approach to the problems of bone-tissue metabolism and more ade quate investigation of the pathogenesis of its miscellaneous abnormalities. Used to study the metabolism of bone mineral in osteoporosis, hypo- and hyperparathy roidism, and other metabolic bone diseases, the new methods have given much valuable information. In malignancy they also promise to supplement the scantiness of the existing information better than the routine examination procedures, yet they have been used far more rarely in this field. The material presented in this work represents an attempt to marshal the facts and to answer, by the aid of recent techniques, some still open problems of bone mineral metabolism in patients with cancer. Since the new techniques involve an entirely new approach, the first two chapters are devoted to it and details of these techniques are presented in the third chapter. I realize the shortcomings of this work, but the never-ending and continuously increasing search for new discoveries makes some data obsolete at the moment of their presentation. Nevertheless, I hope that this work will give some information which will be useful in interpreting disturbances of bone-tissue metabolism in patients, both without any evidence of bone secondaries, and with widespread osseous metas tases.