Understanding Gene And Environmental Interactions For Disease Prevention
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Understanding Gene And Environmental Interactions For Disease Prevention
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Author : Thailand Environmental Mutagen Society
language : en
Publisher:
Release Date : 1998
Understanding Gene And Environmental Interactions For Disease Prevention written by Thailand Environmental Mutagen Society and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Environment categories.
Understanding Gene And Environmental Interactions For Disease Prevention
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Author :
language : en
Publisher:
Release Date : 1999
Understanding Gene And Environmental Interactions For Disease Prevention written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Gene Environment Interactions
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Author : Lucio G. Costa
language : en
Publisher: John Wiley & Sons
Release Date : 2005-12-16
Gene Environment Interactions written by Lucio G. Costa and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-16 with Science categories.
Understanding the play between heredity and environment, and relating it to disease causation, is the task of ecogenetics. Gene-Environment Interactions: Fundamentals of Ecogenetics presents the first comprehensive survey of this discipline, reflecting its relationship with toxicology, epidemiology, pharmacology, public health, and other medical and biological fields. Divided into four sections, the text elucidates key basic and advanced topics: * Section 1 covers fundamentals, including the history of the discipline, a discussion of the molecular laboratory tools currently available to assess genotypes, using such measurements in molecular epidemiology studies, and the statistical issues involved in their analysis. * Section 2 focuses on a number of key genetic polymorphisms relevant for ecogenetics, including enzymes of phase I and phase II metabolism, enzymes involved in DNA repair, as well as receptors and ion channels. This highlights characteristics of selected, widely studied genotypic/phenotypic differences, and allows discussion of how given genetic variations can influence responses to exogenous chemicals. * Section 3 examines gene-environment interactions through a disease-based approach, addressing how genetic polymorphisms can influence susceptibility to various diseases. Chapters cover important disease conditions such as various types of cancer, neurodegenerative diseases, cardiovascular disease, chronic pulmonary diseases, infectious diseases, diabetes, and obesity. * The final section discusses the ethical, legal, and social issues that arise when investigating and evaluating genetic polymorphisms in human populations, as well as the impact of ecogenetics on risk assessment, regulatory policies, and medicine and public health. Packed with clear examples illustrating concepts, as well as numerous tables and figures, Gene-Environment Interactions: Fundamentals of Ecogenetics is a unique resource for a wide range of physicians, students, and other specialists.
Beyond Our Genes
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Author : Raffaele Teperino
language : en
Publisher: Springer Nature
Release Date : 2020-01-24
Beyond Our Genes written by Raffaele Teperino and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-24 with Medical categories.
The genotype/phenotype dichotomy is being slowly replaced by a more complex relationship whereby the majority of phenotypes arise from interactions between one’s genotype and the environment in which one lives. Interestingly, it seems that not only our lives, but also our ancestors’ lives, determine how we look. This newly recognized form of inheritance is known as (epi)genetic, as it involves an additional layer of information on top of the one encoded by the genes. Its discovery has constituted one of the biggest paradigm shifts in biology in recent years. Understanding epigenetic factors may help explain the pathogenesis of several complex human diseases (such as diabetes, obesity and cancer) and provide alternative paths for disease prevention, management and therapy. This book introduces the reader to the importance of the environment for our own health and the health of our descendants, sheds light on the current knowledge on epigenetic inheritance and opens a window to future developments in the field.
Genome Analysis And Human Health
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Author : Leena Rawal
language : en
Publisher: Springer
Release Date : 2017-06-08
Genome Analysis And Human Health written by Leena Rawal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-08 with Medical categories.
This book highlights selected current data and its relevance in the human health care system, offering a fundamental primer on genetics and human health. With the advent of new high-throughput technologies (for the whole genome including exome sequencing), the conventional focus on genetics and individual genes is now shifting toward the analysis of complex genes, gene-gene interactions and the association between genes and environment, including epigenetics. The rapidly changing scientific research landscape, with the ever-growing influx of data on one hand and emergence of newer and more complicated diseases on the other, has created a dilemma for researchers and caregivers, who are still hopeful that advances in genetics and genomics will provide avenues for the understanding, prevention and possible cure of human diseases. The book focuses on the interactions between genes and proteins at both the transcriptome and proteome levels, which in turn affect the human genome and health. Additionally, it covers the domain that must be explored in order to understand the gene-gene and protein-protein interactions that contribute to human health. The book offers a valuable guide for all students and researchers working in the area of molecular genetics and genomics.
Genes Behavior And The Social Environment
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2006-12-07
Genes Behavior And The Social Environment written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-07 with Social Science categories.
Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.
Gene Environment Interactions And Human Diseases
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Author : Lu Qi
language : en
Publisher: Nova Science Publishers
Release Date : 2016
Gene Environment Interactions And Human Diseases written by Lu Qi and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Genotype-environment interaction categories.
With tremendous success of genomic research in discovering genetic variations determining human diseases, it is now time to re-evaluate how the environment affects disease risk by taking into consideration these genetic findings. This book addresses a rapidly growing interest in assessing the relations between environmental risk factors (such as diet, lifestyle) and human diseases, by considering the potential roles of genomic make-up. The book brings together a selection of chapters written by specialists with a variety of backgrounds such as epidemiology, nutrition, genetics, epigenetics, microbiome, biostatistics and bioinformatics. These authors are united in their concerns on the same scientific question how do genomic events modify the effects of traditional, environmental risk factors on disease risk? This book offers an expert overview of the advances in the field of gene-environment interactions on human diseases and the cutting-edge methods used to detect the interactions. The majority of the chapters provide detailed up-to-date descriptions of the major findings of gene-environment interactions on various chronic diseases and risk factors such as obesity, lipids, diabetes, cardiovascular disease, cancer, multiple sclerosis, pancreatitis, Parkinson's disease, and longevity. The book also covers the potential influence of epigenetic events and microbiome on the relation between environment and diseases. In addition, the book also captures the potential application of the findings from this field in personalised prevention and treatment of human diseases.
Genetics And Common Disorders
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Author :
language : en
Publisher:
Release Date : 2005
Genetics And Common Disorders written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Between The Lines Of Genetic Code
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Author : Leonid Padyukov
language : en
Publisher: Academic Press
Release Date : 2013-09-28
Between The Lines Of Genetic Code written by Leonid Padyukov and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-28 with Science categories.
Between the Lines of Genetic Code lays out methodologies and tools for the measurement and evaluation of gene-gene and gene-environment studies and gives perspective on the future of this discipline. The book begins by defining terms for interaction studies, describing methodologies, and critically assessing the viability of current study designs and the possibilities for integrating designs. It then provides recent applications data with case studies in rheumatoid arthritis, multiple sclerosis, myositis and other complex human diseases. Last, it examines current studies and directions for future applications in patient care. Recent multivariate studies show that gene-gene and gene-environment interactions can explain significant variances in inheritance that have previously been undetectable in univariate analysis. These links among genes and between genes and their environments during the development of diseases may serve as important hints for understanding pathogenic mechanisms and for developing new tools for prognosis, diagnosis, and treatment of various diseases. Systematically integrates methods of defining and detecting gene interactions to provide an overview of the field Critically analyzes current methods and tools to aid researchers in integrating gene interaction studies Includes examples of current biomedical applications and presents current research expected to shape clinical research in the near future
Cancer And The Environment
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2002-08-01
Cancer And The Environment written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-08-01 with Science categories.
The Roundtable on Environmental Health Sciences, Research, and Medicine wanted to address the link between environmental factors and the development of cancer in light of recent advances in genomics. They asked what research tools are needed, how new scientific information can be applied in a timely manner to reduce the burden of cancer, and how this can be flexible enough to treat the individual.