Unfolded Protein Response Upr An Impending Target For Multiple Neurological Disorders
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Unfolded Protein Response Upr An Impending Target For Multiple Neurological Disorders
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Author : Safikur Rahman
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-08
Unfolded Protein Response Upr An Impending Target For Multiple Neurological Disorders written by Safikur Rahman and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-08 with Science categories.
Current Thoughts On Dementia
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Author : Ghulam Md Ashraf
language : en
Publisher: Springer Nature
Release Date : 2022-07-06
Current Thoughts On Dementia written by Ghulam Md Ashraf and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-06 with Medical categories.
This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
Progressive Brain Disorders In Childhood
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Author : Juan M. Pascual
language : en
Publisher: Cambridge University Press
Release Date : 2017-04-20
Progressive Brain Disorders In Childhood written by Juan M. Pascual and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-20 with Medical categories.
A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.
Diagnosis And Management Of Ovarian Disorders
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Author : Albert Altchek
language : en
Publisher: Elsevier
Release Date : 2003-09-04
Diagnosis And Management Of Ovarian Disorders written by Albert Altchek and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-04 with Medical categories.
This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine
The M2 Macrophage
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Author : Tamás Röszer
language : en
Publisher: Springer Nature
Release Date : 2020-08-03
The M2 Macrophage written by Tamás Röszer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-03 with Medical categories.
Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of immunity, tissue development and turnover, metabolism, and endocrine signaling. Dysfunction in M2 macrophages can ruin the healthy interplay between the immune system and metabolic processes, and lead to diseases such as insulin resistance, metabolic syndrome, and type 1 and 2 diabetes mellitus. Furthermore, M2 macrophages are essential for healthy tissue development and immunological self-tolerance. Worryingly, these functions of M2 macrophages can also be disrupted, resulting in tumor growth and autoimmunity. This book comprehensively discusses the biology of M2 macrophages, summarizes the current state of knowledge, and highlights key questions that remain unanswered.
Tau Biology
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Author : Akihiko Takashima
language : en
Publisher: Springer
Release Date : 2020-02-25
Tau Biology written by Akihiko Takashima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-25 with Medical categories.
This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death. With the help of new technologies, researchers are now solving these long-standing questions. In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.
Neonatal Anesthesia
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Author : D. Ryan Cook
language : en
Publisher: Davies Publishing
Release Date : 1988
Neonatal Anesthesia written by D. Ryan Cook and has been published by Davies Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.
Protein Misfolding Disorders
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Author : Claudio Hetz
language : en
Publisher: Bentham Science Publishers
Release Date : 2009
Protein Misfolding Disorders written by Claudio Hetz and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.
Neurodegenerative disorders such as Amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), Prion-related disorders (PrD) and Huntington’s disease (HD) share a common neuropathology, primarily featuring the presence of abnormal protein inclusions containing specific misfolded proteins. These groups of diseases are now classified as Protein Misfolding Disorders. This book gives a comprehensive overview of the possible mechanisms involved in Protein Misfolding Disorders and possible therapeutic strategies to treat these diseases. The Ebook provides the most recent evidence addressing the role of cellular stress responses to neurological diseases, along with therapeutic strategies to alleviate ER stress in a disease context. -- Publisher.