Unraveling The Biology Genetics And Host Environmental Interactions Of Acinetobacter
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Unraveling The Biology Genetics And Host Environmental Interactions Of Acinetobacter
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Author : Maria Alejandra Mussi
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-19
Unraveling The Biology Genetics And Host Environmental Interactions Of Acinetobacter written by Maria Alejandra Mussi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with categories.
Despite not being a disease in and of itself, antibiotic resistance could be considered the global epidemic of modern times, since it produces the failure to prevent and treat many infectious diseases. This can ultimately lead to untreatable microbial infections becoming more widespread and this will significantly increase morbidity and mortality. This worldwide problem is estimated to cause millions of deaths per year and could become an even more significant menace to humanity than established illnesses, such as cancer. In February 2017, the World Health Organization (WHO) published a list of antibiotic-resistant “priority pathogens” – a catalogue of 12 families of bacteria which pose the greatest threat to human health - and Acinetobacter baumannii is leading the list. The most critical group includes multidrug-resistant bacteria, which pose a particular threat in hospitals, nursing homes, and among patients whose care requires devices such as ventilators and blood catheters. This group includes Acinetobacter, Pseudomonas, and various Enterobacteriaceae and they are often associated with deadly infections, such as bloodstream infections and pneumonia. Furthermore, these bacteria have become resistant to a large number of antibiotics, including carbapenems and third generation cephalosporins – the best available antibiotics for treating multidrug-resistant bacteria. A. baumannii is a particularly worrisome example and demands attention: This pathogen turned into a menace to humans during the late 70s, likely as a result of intense antibiotic use in hospital settings, and became one of the microorganisms that are challenging the antibiotic era. Its extreme genome plasticity, combined with mechanisms of horizontal genetic transfer, have played a key role in the evolution of this microorganism, as well as its adaptability to unfavorable environments. However, its pathophysiology, as well as the mechanisms leading to its success as a pathogen, are not that simple to unveil. However, what is clear is that the triad of host-pathogen-environment is crucial in selection and establishment of multidrug-resistant clones and outbreaks. Indeed, there are still many aspects of this pathogen that require a deeper understanding - not only regarding mechanisms of resistance but also its global pathophysiology. For example, basic understanding of transmission mechanisms; knowledge of ‘external’ factors modulating persistence of the pathogen; genetic effects on host susceptibility and infectiousness; mechanisms of pathogenicity and their dynamics; and genetic variation of the pathogen affecting virulence and transmissibility are some aspects that would require further study. Furthermore, the importance of other members of the genus as important nosocomial pathogens, such as Acinetobacter nosocomialis, has been increasingly recognized during the last few years.
Diseases Of Coral
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Author : Cheryl M. Woodley
language : en
Publisher: John Wiley & Sons
Release Date : 2016-01-26
Diseases Of Coral written by Cheryl M. Woodley and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-26 with Medical categories.
Coral disease is quickly becoming a crisis to the health and management of the world’s coral reefs. There is a great interest from many in preserving coral reefs. Unfortunately, the field of epizootiology is disorganized and lacks a standard vocabulary, methods, and diagnostic techniques, and tropical marine scientists are poorly trained in wildlife pathology, veterinary medicine, and epidemiology. Diseases of Coral will help to rectify this situation.
Quorum Sensing
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Author : Saurabh Sudha Dhiman
language : en
Publisher:
Release Date : 2021
Quorum Sensing written by Saurabh Sudha Dhiman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Science categories.
New developments in researching quorum sensing Microbial growth affects industries as diverse as agriculture, engineering, and medicine, to name a few. As more precise solutions are needed for modern challenges, researchers must understand the mechanisms of microbial growth. Quorum sensing (QS) is an essential part of microbial growth, and this work contains key areas such as signal molecules; mechanisms of signal transfer, role, and type of signal receptors; quorum quenching; characterization of microbial plasmids in quorum sensing; and novel and underexplored molecules involved in QS, along with therapeutic roles of quorum sensing inhibitors. This volume is perfect for researchers working on microbiology or biotechnology.
Ticks And Tick Borne Pathogens
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Author : Muhammad Abubakar
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-03-13
Ticks And Tick Borne Pathogens written by Muhammad Abubakar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-13 with Medical categories.
It is vital to understand ticks and tick-borne pathogens as well as their impact on humans. This book is intended for students in parasitology, biologists, parasitologists involved in molecular diagnostics of tick-borne diseases, practicing veterinarians, and for others who may require information on ticks and tick-borne diseases. Here we have put together a collection of chapters focused on different aspects of ticks and tick-borne diseases mainly to provide the reader with novel information in the field, but not the basic generalised information provided by many textbooks. This book includes topics such as high-throughput technologies in diagnosis, discovery of novel tick vaccines, identification of new pathogens transmitted by ticks, and new epidemiological information of certain well-known ticks and tick-borne diseases. These chapters were authored by parasitologists from all over the world, giving an insight to the reader about significant ticks and tick-borne diseases prevalent in those particular geographical regions with the local expert's point of view. Each of the chapters has separate reference lists, making it easier for the reader to find additional reading material related to their topic of interest.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1997
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medicine categories.
Principles Of Plant Microbe Interactions
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Author : Ben Lugtenberg
language : en
Publisher: Springer
Release Date : 2014-12-04
Principles Of Plant Microbe Interactions written by Ben Lugtenberg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-04 with Science categories.
The use of microbial plant protection products is growing and their importance will strongly increase due to political and public pressure. World population is growing and the amount of food needed by 2050 will be double of what is produced now whereas the area of agricultural land is decreasing. We must increase crop yield in a sustainable way. Chemical plant growth promoters must be replaced by microbiological products. Also here, the use of microbial products is growing and their importance will strongly increase. A growing area of agricultural land is salinated. Global warming will increase this process. Plants growth is inhibited by salt or even made impossible and farmers tend to disuse the most salinated lands. Microbes have been very successfully used to alleviate salt stress of plants. Chemical pollution of land can make plant growth difficult and crops grown are often polluted and not suitable for consumption. Microbes have been used to degrade these chemical pollutants.
Endospore Forming Soil Bacteria
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Author : Niall A. Logan
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-07-06
Endospore Forming Soil Bacteria written by Niall A. Logan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-06 with Science categories.
Aerobic endospore-forming bacteria are found in soils of all kinds, ranging from acid to alkaline, hot to cold, and fertile to desert. It is well known that endospores confer special properties upon their owners and play dominant parts in their life cycles and dispersal, and much has been written about the spores, genetics, and economic importance of these organisms. Much has also been written about soil ecology, but there is a relative dearth of literature that brings together different aspects of the behaviour and characters of endospore-formers with their contributions to soil ecosystems. This Soil Biology volume fills that gap. Following chapters that describe the current classification of these organisms, that review methods for their detection and for studying their life cycles in soils, and that examine their dispersal, other chapters show that they are active and dynamic members of soil floras that interact widely with other soil inhabitants, with roles in nitrogen fixation, denitrification, and soil remediation.
Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery
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Author : Busi Siddhardha
language : en
Publisher: Springer Nature
Release Date : 2020-03-28
Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery written by Busi Siddhardha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-28 with Science categories.
This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
Microorganisms In Sustainable Agriculture And Biotechnology
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Author : Tulasi Satyanarayana
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-03
Microorganisms In Sustainable Agriculture And Biotechnology written by Tulasi Satyanarayana and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-03 with Science categories.
This review of recent developments in our understanding of the role of microbes in sustainable agriculture and biotechnology covers a research area with enormous untapped potential. Chemical fertilizers, pesticides, herbicides and other agricultural inputs derived from fossil fuels have increased agricultural production, yet growing awareness and concern over their adverse effects on soil productivity and environmental quality cannot be ignored. The high cost of these products, the difficulties of meeting demand for them, and their harmful environmental legacy have encouraged scientists to develop alternative strategies to raise productivity, with microbes playing a central role in these efforts. One application is the use of soil microbes as bioinoculants for supplying nutrients and/or stimulating plant growth. Some rhizospheric microbes are known to synthesize plant growth-promoters, siderophores and antibiotics, as well as aiding phosphorous uptake. The last 40 years have seen rapid strides made in our appreciation of the diversity of environmental microbes and their possible benefits to sustainable agriculture and production. The advent of powerful new methodologies in microbial genetics, molecular biology and biotechnology has only quickened the pace of developments. The vital part played by microbes in sustaining our planet’s ecosystems only adds urgency to this enquiry. Culture-dependent microbes already contribute much to human life, yet the latent potential of vast numbers of uncultured—and thus untouched—microbes, is enormous. Culture-independent metagenomic approaches employed in a variety of natural habitats have alerted us to the sheer diversity of these microbes, and resulted in the characterization of novel genes and gene products. Several new antibiotics and biocatalysts have been discovered among environmental genomes and some products have already been commercialized. Meanwhile, dozens of industrial products currently formulated in large quantities from petrochemicals, such as ethanol, butanol, organic acids, and amino acids, are equally obtainable through microbial fermentation. Edited by a trio of recognized authorities on the subject, this survey of a fast-moving field—with so many benefits within reach—will be required reading for all those investigating ways to harness the power of microorganisms in making both agriculture and biotechnology more sustainable.
Chemical Biology
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Author : Jonathan E. Hempel
language : en
Publisher: Humana
Release Date : 2016-09-24
Chemical Biology written by Jonathan E. Hempel and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-24 with Science categories.
This volume seeks to enable the discovery of tools in chemical biology by providing readers with various techniques ranging from initial chemical genetic screening to target identification. To successfully highlight the essential components of the chemical biology tool discovery process, the book is organizes into four parts that focus on platforms for molecular discovery in in vitro cellular systems, in vivo chemical genetic screening protocols, and methods used to discover functional protein targets. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Practical and informative, Chemical Biology: Methods and Protocols seeks to improve the success rate of the chemical biology field through the dissemination of detailed and experiential knowledge.