Using Animal Models In Biomedical Research
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Using Animal Models In Biomedical Research
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Author : Pierce K. H. Chow
language : en
Publisher: World Scientific
Release Date : 2008
Using Animal Models In Biomedical Research written by Pierce K. H. Chow and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
Ch. 1. Scientific considerations and choice of species. ch. 1.1. The rationale for the use of animal models in biomedical research / Pierce Chow. ch. 1.2. Experimental animal models in biomedical resarch / Robert Ng. ch. 1.3. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- ch. 2. Regulatory considerations in the use of animal models. ch. 2.1. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. ch. 2.2. The functions of the institutional animal care and use committee / Pierce Chow. ch. 2.3. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. ch. 2.4. The 3R's, research variables and the use of alternatives / Hock Soo Ong. ch. 2.5. Use of statistics as determinant for number of animals used / Huihua Li. ch. 2.6. The advantages of accreditation with AAALAC / Bryan Ogden -- ch. 3. Animal handling and surgical procedures. ch. 3.1. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. ch. 3.2. Blood collection from laboratory animals / Jason Villano. ch. 3.3. Antibiotic coverage and therapy / Darvi Sergio. ch. 3.4. Animal preparation and transport / Robert Ng. ch. 3.5. Preparation and implementation of animal surgery / Robert Ng. ch. 3.6. Animal intubation / Robert Ng. ch. 3.7. Anaesthesia and maintenance of homeostasis / Robert Ng. ch. 3.8. Animal euthanasia / Darvi Sergio. ch. 3.9. Rodent sentinel programme / Peik Khin Tan -- ch. 4. Basic animal investigative methods. ch. 4.1. Bioimaging in animals / David Ng [und weitere]. ch. 4.2. Histology sampling and techniques / In Chin Song. ch. 4.3. Animal tissue perfusion and preservation / Robert Ng. ch. 4.4. Animal cell culture / Kai Zhang and Peggy Yong. ch. 4.5. Application of microsurgical techniques in animal research / Bien Keem Tan [und weitere] -- ch. 5. Animal welfare considerations. ch. 5.1. Species specific caging configuration and design / Cindy Phua. ch. 5.2. Postoperative care and pain management / Jason Villano. ch. 5.3. Animal feeds and nutritional requirements / Peik Khin Tan -- ch. 6. Safety management of an animal facility. ch. 6.1. Occupational health and safety programme / Angela Goh. ch. 6.2. New employee and external users orientation / Inria Kurniawan Then. ch. 6.3. Radiation safety awareness in animal research / S. Somanesan. ch. 6.4. Emergency crisis management / Irene Kee. ch. 6.5. Zoonoses and laboratory animal allergies / Jason Villano -- ch. 7. Supporting facilities design. ch. 7.1. Clinical skills laboratory / Robert Ng. ch. 7.2. Animal research supporting laboratories / Robert Ng. ch. 7.3. Animal research and housing facilities / Robert Ng -- ch. 8. The development of comprehensive animal facilities in Singapore. ch. 8.1. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng
Sourcebook Of Models For Biomedical Research
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Author : P. Michael Conn
language : en
Publisher: Springer Science & Business Media
Release Date : 2008
Sourcebook Of Models For Biomedical Research written by P. Michael Conn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.
Animal Models For The Study Of Human Disease
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Author : P. Michael Conn
language : en
Publisher: Academic Press
Release Date : 2013-05-29
Animal Models For The Study Of Human Disease written by P. Michael Conn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-29 with Science categories.
Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease
Using Animal Models In Biomedical Research
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Author :
language : en
Publisher:
Release Date : 2008
Using Animal Models In Biomedical Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Animal models in research categories.
Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials. A practical understanding of the choice, care and use of animal models is thus expected and required of all biomedical researchers. However, while both legislations and the practice of laboratory animal science have made great advances in the last decade and have impacted significantly on the use of animal models, this corpus of knowledge is not readily available in formats easily digestible to the average biomedical researcher. This book fills this gap in knowledge and provides material not easily sourced by the average biomedical researcher, such as current information on bioimaging, occupational health and biosafety, animal protocol design and histological-pathological support.
Principles Of Molecular Cardiology
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Author : Marschall S. Runge
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-14
Principles Of Molecular Cardiology written by Marschall S. Runge and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-14 with Medical categories.
An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.
Animal Models In Biomedical Research
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Author :
language : en
Publisher: DIANE Publishing
Release Date : 1993-07
Animal Models In Biomedical Research written by and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-07 with Animal models in research categories.
Refinements To Animal Models For Biomedical Research
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Author : Gabrielle C. Musk
language : en
Publisher: MDPI
Release Date : 2021-04-06
Refinements To Animal Models For Biomedical Research written by Gabrielle C. Musk and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-06 with Science categories.
There is some talk about an antibiotic Armageddon, wherein untreatable post-operative infections and similarly untreatable complications after chemotherapy will occur. The now famous “O’Neill Report” suggests that, by 2050, more people could die from resistant bacterial infections than from cancer. We are still learning about all the subtle drivers of antibiotic resistance, realizing that we need a single “whole health” coordinated policy. We ingest what we sometimes feed to animals, yet there does not seem to be any new classes of antibiotics on the horizon. Maybe there is something that has been around forever that could could to our rescue: bacteriophages. Nevertheless, we have to do things differently. We must use antibiotics appropriately and for the correct indication, duration, and dosage with good practice and stewardship.. While by no means comprehensive, this book covers many topics regarding antibiotic stewardship. It also addresses older antibiotics, new combinations, and even new agents. Last but not least, this book features two excellent articles on bacteriophages. Refinements to animal models used in research for either human or animal benefit must be an ongoing aim for anyone working in this context, whether it be as an animal carrier, an animal user, a veterinarian, or an official. Unfortunately, the details of refinements are often overlooked in publications describing the research outcomes. This book includes manuscripts published in the Animals Special Issue “Refinements to Animal Models for Biomedical Research”. In this contemporary resource, we included 12 peer-reviewed papers that cover a range of approaches to the concept of refinement.
Use Of Laboratory Animals In Biomedical And Behavioral Research
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1988-02-01
Use Of Laboratory Animals In Biomedical And Behavioral Research written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-02-01 with Science categories.
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Animal Models In Biomedical Research
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Author : Cynthia Petrie Smith
language : en
Publisher:
Release Date : 1991
Animal Models In Biomedical Research written by Cynthia Petrie Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Animal models in research categories.
Animal Models In Biomedical Research
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Author : Cynthia Petrie Smith
language : en
Publisher:
Release Date : 1992
Animal Models In Biomedical Research written by Cynthia Petrie Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Animal models in research categories.