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Using Cancer Omics To Understand Cancer

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Using Cancer Omics To Understand Cancer

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Author : Daoud Meerzaman
language : en
Publisher: Frontiers Media SA
Release Date : 2020-10-23

Using Cancer Omics To Understand Cancer written by Daoud Meerzaman and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-23 with Medical categories.

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Using Cancer Omics To Understand Cancer

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Author : Daoud Meerzaman
language : en
Publisher:
Release Date : 2020

Using Cancer Omics To Understand Cancer written by Daoud Meerzaman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.

Omics Approaches In Breast Cancer

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Author : Debmalya Barh
language : en
Publisher: Springer
Release Date : 2014-10-13

Omics Approaches In Breast Cancer written by Debmalya Barh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-13 with Medical categories.

Breast cancer is the most common cancer in females that accounts for highest cancer specific deaths worldwide. In the last few decades research has proven that breast cancer can be treated if diagnosed at early stages and proper therapeutic strategy is adopted. Omics-based recent approaches have unveiled the molecular mechanism behind the breast tumorigenesis and aid in identification of next-generation molecular markers for early diagnosis, prognosis and even the effective targeted therapy. Significant development has taken place in the field of omics in breast cancer in the last decade. The most promising omics approaches and their outcomes in breast cancer have been presented in this book for the first time. The book covers omics technologies and budding fields such as breast cancer miRNA, lipidomics, epigenomics, proteomics, nutrigenomics, stem cell, pharmacogenomics and personalized medicine and many more along with conventional topics such as breast cancer management etc. It is a research-based reference book useful for clinician-scientists, researchers, geneticists and health care industries involved in various aspects of breast cancer. The book will also be useful for students of biomedicine, pathology and pharmacy.

An Omics Perspective On Cancer Research

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Author : William C.S. Cho
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-07

An Omics Perspective On Cancer Research written by William C.S. Cho and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-07 with Medical categories.

Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality will provide a knowledge base which changes the face of cancer understanding and therapeutics. This is the first book to provide such a comprehensive coverage of a rapidly evolving area written by leading experts in the field of omics. It complies and details cutting-edge cancer research that covers the broad advances in the field and its application from cancer-associated gene discovery to drug target validation. It also highlights the potential of using integration approach for cancer research. This unique and timely book provides a thorough overview of developing omics, which will appeal to anyone involved in cancer research. It will be a useful reference book for graduate students of different subjects (medicine, biology, engineering, etc) and senior scientists interested in the fascinating area of advanced technologies in cancer research. Readership: This is a precious book for all types of readers – cancer researchers, oncologists, pathologists, biologists, clinical chemists, pharmacologists, pharmaceutical specialists, biostatisticians, and bioinformaticists who want to expand their knowledge in cancer research.

Translational Research And Onco Omics Applications In The Era Of Cancer Personal Genomics

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Author : Erika Ruiz-Garcia
language : en
Publisher: Springer Nature
Release Date : 2019-11-11

Translational Research And Onco Omics Applications In The Era Of Cancer Personal Genomics written by Erika Ruiz-Garcia and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-11 with Science categories.

Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.

Essentials Of Cancer Genomic Computational Approaches And Precision Medicine

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Author : Nosheen Masood
language : en
Publisher: Springer Nature
Release Date : 2020-03-20

Essentials Of Cancer Genomic Computational Approaches And Precision Medicine written by Nosheen Masood and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-20 with Medical categories.

This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.

Systems Biology Of Tumor Physiology

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Author : David H. Nguyen
language : en
Publisher: Springer
Release Date : 2015-12-11

Systems Biology Of Tumor Physiology written by David H. Nguyen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-11 with Medical categories.

This exciting SpringerBrief presents evidence for new ideas that will challenge several theories of how cancer biology is understood. Cancer biology has undergone several intellectual revolutions in the past 50 years. A mutation-centric view of cancer has given way to the tumor microenvironment view. Reductionistic studies of one gene at a time have given way to systems biology approaches that analyze the whole genome (omics) at the same time. However, this text combines the complex levels studying cancer at the molecular biology level, endocrinology level, and transcriptomics level. What researchers are now realizing is that there is a need to combine omics with physiology concepts in order to better understand cancer and this book will give insight to the merging of these two fields in order to define how cancer is studied in the future.

Essentials Of Cancer Genomic Computational Approaches And Precision Medicine

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Author :
language : en
Publisher:
Release Date : 2020

Essentials Of Cancer Genomic Computational Approaches And Precision Medicine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Cancer categories.

Computational Systems Biology Approaches In Cancer Research

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Author : Inna Kuperstein
language : en
Publisher: CRC Press
Release Date : 2019-09-09

Computational Systems Biology Approaches In Cancer Research written by Inna Kuperstein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-09 with Computers categories.

Praise for Computational Systems BiologyApproaches in Cancer Research: "Complex concepts are written clearly and with informative illustrations and useful links. The book is enjoyable to read yet provides sufficient depth to serve as a valuable resource for both students and faculty." — Trey Ideker, Professor of Medicine, UC Xan Diego, School of Medicine "This volume is attractive because it addresses important and timely topics for research and teaching on computational methods in cancer research. It covers a broad variety of approaches, exposes recent innovations in computational methods, and provides acces to source code and to dedicated interactive web sites." — Yves Moreau, Department of Electrical Engineering, SysBioSys Centre for Computational Systems Biology, University of Leuven With the availability of massive amounts of data in biology, the need for advanced computational tools and techniques is becoming increasingly important and key in understanding biology in disease and healthy states. This book focuses on computational systems biology approaches, with a particular lens on tackling one of the most challenging diseases - cancer. The book provides an important reference and teaching material in the field of computational biology in general and cancer systems biology in particular. The book presents a list of modern approaches in systems biology with application to cancer research and beyond. It is structured in a didactic form such that the idea of each approach can easily be grasped from the short text and self-explanatory figures. The coverage of topics is diverse: from pathway resources, through methods for data analysis and single data analysis to drug response predictors, classifiers and image analysis using machine learning and artificial intelligence approaches. Features Up to date using a wide range of approaches Applicationexample in each chapter Online resources with useful applications’

Integrative Multi Omics Analysis To Understand Cancer And Anticancer Therapy

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Author : Michelle Ting Dow
language : en
Publisher:
Release Date : 2020

Integrative Multi Omics Analysis To Understand Cancer And Anticancer Therapy written by Michelle Ting Dow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.

Precision cancer medicine promises better treatments to a disease as complex and heterogenous as cancer. Many anti-cancer therapies are beneficial to only a subset of patients due to the variability in patient genetic and tumor heterogeneity. Thus, we need better frameworks for understanding underlying genomic and transcriptomic patterns influencing differential patient outcomes, yet our understanding of how genetic alterations connect to treatment in in vivo and in vitro models remains understudied. To address this gap, I utilized human patient data from The Cancer Genome Atlas (TCGA), hepatocellular carcinoma (HCC) models, prostate cancer (PCa) models, and chronic myelogenous leukemia (CML) cell lines. Through the integration of multi-omic data, I identified parallel features of human and model organism data that could reveal disease specific characteristics. Additionally, I characterized the landscape of acquired resistance for a panel of chemotherapeutic treatments and revealed potential alleles and genes that mediate the process. The analyses I conducted expose the role of genetic information and suggest future applications for development of precision medicine.

Using Cancer Omics To Understand Cancer

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