Using Novel Technologies And Models To Identify Biomarkers And Explore Therapeutic Strategies For Neurological Disorders
DOWNLOAD
Download Using Novel Technologies And Models To Identify Biomarkers And Explore Therapeutic Strategies For Neurological Disorders PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Using Novel Technologies And Models To Identify Biomarkers And Explore Therapeutic Strategies For Neurological Disorders book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Using Novel Technologies And Models To Identify Biomarkers And Explore Therapeutic Strategies For Neurological Disorders
DOWNLOAD
Author : Dongdong Qin
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-20
Using Novel Technologies And Models To Identify Biomarkers And Explore Therapeutic Strategies For Neurological Disorders written by Dongdong Qin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-20 with Science categories.
Biomarker Exploration In Neuropsychiatry Understanding Of The Pathophysiology And Therapeutic Implications
DOWNLOAD
Author : HuaLin Cai
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-25
Biomarker Exploration In Neuropsychiatry Understanding Of The Pathophysiology And Therapeutic Implications written by HuaLin Cai and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-25 with Science categories.
Biomarkers Of Brain Injury And Neurological Disorders
DOWNLOAD
Author : Kevin K. W. Wang
language : en
Publisher: CRC Press
Release Date : 2014-10-28
Biomarkers Of Brain Injury And Neurological Disorders written by Kevin K. W. Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-28 with Medical categories.
This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies used to identify these biological markers. The book includes findings from "Omics research" that have been utilized to decipher and identify such biomarkers. It discusses protein, microRNA, and altered gene profiles and reviews neurological disorders such as multiple sclerosis, Charcot-Marie-Tooth disease, and prion and Alzheimer’s disease.
Advances In Parkinson S Disease Research Exploring Biomarkers And Therapeutic Strategies For Halting Disease Progression
DOWNLOAD
Author : Carmen Venegas
language : en
Publisher: Frontiers Media SA
Release Date : 2025-08-19
Advances In Parkinson S Disease Research Exploring Biomarkers And Therapeutic Strategies For Halting Disease Progression written by Carmen Venegas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-08-19 with Science categories.
Parkinson’s disease (PD) is the fastest-growing neurodegenerative disorder, being prevalent in 1% of people aged above 65 years. PD is characterized by dopaminergic neurons and the accumulation of alpha-synuclein (α-syn)-rich protein in Lewy bodies. Although aging is the highest risk factor for developing PD, the genetic predisposition and exposure to environmental factors such as herbicides or pesticides can induce oxidative stress, DNA damage, and neuronal death contributing to PD pathogenesis. To date, there is not a therapy to halt the disease. Many studies have shown multiple altered pathways offering different approaches for developing an effective therapy, however, the current therapies are merely symptomatic, and they include a substitution of dopamine by the administration of Levodopa, the use of catechol-O- O -methyltransferase inhibitors, monoamine oxidase inhibitors or Dopamine agonist among others. However, these treatments can only relieve some of the symptoms, they do not slow the progression of the disease and they have limited long-term efficacy.
Proteostasis
DOWNLOAD
Author : Nidhi Puranik
language : en
Publisher: Springer Nature
Release Date : 2025-07-12
Proteostasis written by Nidhi Puranik and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-12 with Science categories.
This book explores the role of proteostasis in neurodegenerative disorders, focusing on protein homeostasis in long-lived, nondividing cells like neurons. It examines how disruptions in proteostasis, influenced by factors such as oxidative stress, aging, and environmental stress, contribute to diseases like Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis. The book begins with an overview of the epidemiology and management of neurodegenerative diseases. Subsequent chapters delve into the mechanisms governing proteostasis, highlighting the ubiquitin-proteasome system, molecular chaperones, and co-chaperones in protein folding and degradation. It further explores how impairments in these pathways contribute to neuroinflammation and disease progression. By providing insights into these cellular processes, the book aims to enhance understanding and support the development of potential therapeutic strategies.
Revolutions In Human Biospecimen Study Leveraging New Technologies To Explore The Pathology Therapeutics And Biomarkers For Atherosclerotic Disease
DOWNLOAD
Author : Ying Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-20
Revolutions In Human Biospecimen Study Leveraging New Technologies To Explore The Pathology Therapeutics And Biomarkers For Atherosclerotic Disease written by Ying Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-20 with Medical categories.
Over the last few years, new high-throughput biotechnologies are revolutionizing our ways to utilize human biospecimens for understanding atherosclerotic disease. These recent advances allow deep profiling of individual cells at the genomics, epigenomics, transcriptomics and proteomics levels, or even simultaneous detection of various combinations of ‘Omics’ in the same cell. Additionally, novel methods to integrate data at different levels from tissue sections and dissociated tissues are the emerging trends in large and institutional biobank studies. Growing literature has shown the value of such sequencing and bioinformatic strategies in shedding light on (1) how risk genes, as identified by the Genome-Wide Association Study, contribute to atherogenesis (genotype to phenotype), and (2) how features of atherosclerotic lesions affect patient response in clinical trials (phenotype to the clinical outcome). The hybrid of cutting-edge biotechnologies and bioinformatic approaches helps us maximize biobank resources to accelerate bench-to-bedside research.
Machine And Deep Learning Solutions For Achieving The Sustainable Development Goals
DOWNLOAD
Author : Ruiz-Vanoye, Jorge A.
language : en
Publisher: IGI Global
Release Date : 2025-03-07
Machine And Deep Learning Solutions For Achieving The Sustainable Development Goals written by Ruiz-Vanoye, Jorge A. and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-07 with Computers categories.
Achieving the United Nations' Sustainable Development Goals (SDGs) requires innovative solutions that address global challenges such as climate change, poverty, and social inequality. Artificial intelligence (AI), machine learning, and data-driven technologies offer transformative potential by optimizing resource management, improving healthcare outcomes, and enhancing decision-making processes. However, integrating AI into sustainable development efforts presents ethical, technical, and policy-related challenges that must be carefully navigated. A multidisciplinary approach is essential to ensure these technologies are applied inclusively and responsibly, maximizing their positive societal impact. Machine and Deep Learning Solutions for Achieving the Sustainable Development Goals enhances understanding and application of machine learning, deep learning, data mining and AI technologies in the context of the SDGs. It fills the gap by linking theory and practice and addresses both the opportunities and challenges inherent in this intersection. Covering topics such as demand side management, agricultural productivity, and smart manufacturing, this book is an excellent resource for engineers, computer scientists, practitioners, policymakers, professionals, researchers, scholars, academicians, and more.
The Handbook Of Nanomedicine
DOWNLOAD
Author : Kewal K. Jain
language : en
Publisher: Humana Press
Release Date : 2017-03-20
The Handbook Of Nanomedicine written by Kewal K. Jain and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-20 with Technology & Engineering categories.
Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals as well as nanooncology, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible. In depth and cutting-edge, The Handbook of Nanomedicine, Third Edition informs its readers of the ever-growing field of nanomedicine, destined to play a significant role in the future of healthcare.
Linking Treatment Target Identification To Biological Mechanisms Underlying Mood Disorders
DOWNLOAD
Author : Shaohua Hu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-25
Linking Treatment Target Identification To Biological Mechanisms Underlying Mood Disorders written by Shaohua Hu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-25 with Medical categories.
Clinical Molecular Medicine
DOWNLOAD
Author : Dhavendra Kumar
language : en
Publisher: Academic Press
Release Date : 2019-11-30
Clinical Molecular Medicine written by Dhavendra Kumar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-30 with Science categories.
Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more