Vaccines On Trial
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Statistics In Clinical Vaccine Trials
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Author : Jozef Nauta
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-07
Statistics In Clinical Vaccine Trials written by Jozef Nauta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-07 with Mathematics categories.
This monograph offers well-founded training and expertise on the statistical analysis of data from clinical vaccine trials, i.e., immunogenicity and vaccine field efficacy studies. The book's scope is practical rather than theoretical. It opens with two introductory chapters on the immunology of vaccines to provide readers with the necessary background knowledge. It then continues with an in-depth exploration of the statistical methodology. Many real-life examples and SAS codes are presented, making application of the methods straightforward. Topics discussed include maximum likelihood estimation for censored antibody titers, ANCOVA for antibody values, analysis of equivalence and non-inferiority immunogenicity trial data, analysis of data from vaccine field efficacy trials (including data from studies with recurrent infection data), fitting protection curves to data of challenge or field efficacy studies, and the analysis of vaccine safety data.
Vaccines On Trial
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Author : Pierre Clair
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2017-12-19
Vaccines On Trial written by Pierre Clair and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-19 with categories.
Mandatory shots or freedom to choose? Mandatory vaccination is sweeping across North America, Europe, and Australia. Parental rights to informed consent before medical intervention of children is being revoked. Pediatricians assure us: adverse vaccine reactions are rare. 1. The Association of American Physicians and Surgeons (AAPS) disputes this assurance. "The CDC admits that the reported number of adverse effects of vaccines is probably only 10% of actual adverse effects." - Fact Sheet on Mandatory Vaccinations, April 9/2009 2. After examining many vaccine studies the U.S. Supreme Court ruled: "Vaccines are unavoidably unsafe and there shall be no more lawsuits against any vaccine company." - Bruesewitz v. Wyeth 2011 3. AAPS doesn't favor vaccine mandates. As stated in their Fact Sheet they "attempted to halt government or school districts from blanket vaccine mandates that violate parental Informed Consent." Studies by leading healthcare scientists: 4. Charts and graphs on increasing vaccines rank the U.S. 34th for infant mortality among first world nations. 5. Scientific studies in the U.S, Germany, Sweden, and New Zealand comparing vaccinated and unvaccinated children show unvaccinated kids to be healthier than their vaccinated peers. 6. The book, Critical Vaccine Studies, lists 400 case studies showing vaccinated kids have more health problems later in life. Vaccine Ingredients: 7. The MMR vaccine has DNA material from chicken and cow embryos. 8. MMR also has human DNA from aborted fetuses, listed as WI-38 by the CDC. 9. Many vaccines contain mercury, aluminum, and formaldehyde. How many shots is too many? Before 1970, American kids were fully vaccinated with 2 shots. By 1986, it was 10 shots. Today, kids have to get 24 shots before the age of two. That's a shot/month of foreign DNA injected into a baby's developing body. It's unprecedented in human history. The Internet has transformed the landscape. Pro-vax parents became anti-vax when their kids suffered harmful side-effects. The anti-vax movement began when outraged parents became warriors to protect children injured by adverse vaccine reactions. Today you can chat online with mothers of vaccine-injured kids, read books about toddlers harmed by vaccines, and watch films documenting how autism appears after vaccination, not before. Vaccines on Trial examines the mandatory vaccine issue: Whether it's more noble to suffer our fate, allow our children to be vaccinated against our will, and accept that there may be adverse reactions; or to stand strong, demand informed consent, stop forced vaccines for youngsters, and empower parents to make informed decisions to keep kids safe because every child's genetic makeup is unique. Do benefits outweigh risks? Benefits don't harm children. So this book documents the vaccine risks they will face. Informed consent recognizes the democratic/parental right to avoid risky/unwanted medical intervention on our kids. Parents have a legal right to choose. They're not against vaccines, they're against the use of force. Mandatory vaccines is a far more complex issue than simple pro-vax and anti-vax labels that some people portray with petty black-and-white rhetoric. This book examines vaccines from the medical perspective, legal perspective, scientific perspective, business perspective. ethical perspective, historical perspective, parent's perspective, and the child's perspective. Informed people don't cause strife between families with opposite views on vaccines. Look at the scientific studies referenced here to decide the issues for yourself. Every insight, insider tip, and jewel of wisdom is organized into a comprehensive guide. Learn lessons that may save years of heartbreak, and thousands on hospital bills.
Covid 19 On Trial
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Author : Rui Alexandre Gabirro
language : en
Publisher: Hospitallers Order of the Good News
Release Date : 2021-07-04
Covid 19 On Trial written by Rui Alexandre Gabirro and has been published by Hospitallers Order of the Good News this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-04 with Health & Fitness categories.
COVID-19 ON TRIAL Critical Analyses of a “Pandemic” Introduction 1 Chapter 1 The Nuremberg Code..................................................................3 Nuremberg 2.0.............................................................................4 WMA Declaration of Helsinki....................................................6 Informed Consent........................................................................6 The Vaccine Programme Has Been Rolled out in Breach of the Legal Requirements for Clinicians to obtain the Free and Informed Consent of Those Being Vaccinated................................................7 Three Major Questions................................................................8 UNESCO Universal Declaration on Bioethics and Human Rights.............................................................................................10 BILD Asks all Children for their Forgiveness!.........................11 Wire Fraud.................................................................................13 CDC Study Finds 78% of People Hospitalized for Covid were Overweight or Obese.....................................................................13 Yellow Card Scheme Shows.....................................................14 Chapter 2 Single Source of Truth...............................................................16 Everything Is Prohibited............................................................16 COVILAND..............................................................................17 The First Social Media Virus.....................................................17 COVID-19 Has Caused 6.9 Million Deaths Globally, More Than Double what Official Reports Show..........................19 Institute for Health Metrics and Evaluation, University of Washington....................................................................................22 France & Germany Falsified ICU Bed Occupancy Figures to Justify Sanitary Restrictions..........................................................26 World Average Annual Number of Deaths................................27 The PCR Test Farce...................................................................28 I Discovered That There Was No Evidence That There Was A Virus...............................................................................................29 Eric Clapton after COVID Vaccination: “I Should Never Have Gone Near the Needle”..................................................................34 India Mucormycosis..................................................................35 The Epidemiology of Mucormycosis in India...........................37 Malnutrition and Pollution India's Biggest Health Hazard.......38 Trained Dogs can Detect Odour of COVID-19.........................39 Virus or Fecal Samples..............................................................39 The Virus Transmission Farce...................................................42 Medical Trade Propaganda........................................................42 Christian Drosten - The Real Face of the Coronavirus Farce...43 Corona-Explainer-In-Chief.......................................................43 German Government Advisory Board on Global Health..........45 The Virus Farce.........................................................................47 Clear Line on Nails A Symptoms of Covid-19.........................48 Sneezing is A “Classic” Symptoms of Covid-19......................48 Professor Timothy Spector........................................................49 The Emerging Field of Epigenetics...........................................50 Future of Jobs............................................................................51 We Tried to Infect Covid-19 into Bats, it Doesn't Grow Well in Bats................................................................................................52 The Variants of Concern and Emerging Mutations Farce.........52 Joint Biosecurity Centre............................................................53 Triple Mutant Variant................................................................54 Lying to Everybody...................................................................55 The Covid-19 Vaccine Farce.....................................................55 Spike Protein is a Toxin.............................................................56 Ingredients (as reported in the prescribing information) included in mRNA COVID-19 Vaccines.......................................60 SM-102 in Cloroform................................................................60 Safety Data Sheet......................................................................61 Vaccine Deaths..........................................................................63 Covid19 Vaccine Reports in USA.............................................64 Covid-19 Vaccine is a “Gene Therapy”....................................65 Defense Advanced Research Projects Agency..........................67 DARPA Awards Moderna Therapeutics a Grant for up to $25 Million to Develop Messenger RNA Therapeutics.................68 Australia Drugs Regulator Never Seen the Study Data............69 UK Drugs Regulator We Didn't Read the Clinical Trial...........69 They Don't Understand What They Are Doing.........................70 We Have Essentially Been Taken Over by the Medical Trade Taliban............................................................................................71 Chapter 3 Follow the Money......................................................................73 The UK Government Business Plan..........................................74 Government Wants to Sell Your Medical Records....................74 Britain’s Status as a Scientific Superpower...............................75 The Plan is Predicated...............................................................76 The Bill Gates Business Plan....................................................77 CEPI - A New Organization Will Help Accelerate the Development of Vaccines..............................................................81 A Global Treaty on Pandemic Preparedness / Zoonotic Research Hubs................................................................82 UK Government Funds 8 Vaccine Passport Schemes...............83 Covid-19 Vaccine Passport........................................................83 Accelerate Genomic Medicine..................................................84 Chris Whitty..............................................................................84 Genomics...................................................................................85 Health Data................................................................................85 Applying Behavioural Science and Social Sciences in Health.............................................................................................85 Bill Gates and George Soros Buy Covid Test Company...........87 The Global South Market: Latin America, Asia, Africa, and Oceania..........................................................................................87 Mologic.....................................................................................87 A Very Terrorised Country.........................................................89 We Have Been Fed a Diet of Fear and Scaremongering...........91 How Does Lack of Oxygen Affect the Brain?..........................91 “Long Covid” a Disability Eligible for Accommodation under Civil Rights Law............................................................................92 Deployment of Covert Psychologic Interventions....................93 The Modelling Farce.................................................................94 NHS (UK) Sells Patients Medical Records to Companies........95 We Expect this Positive Momentum to Continue.....................96 Pfizer Wants Military Bases & Bank Reserves as Collateral....97 Who owns Pfizer?.....................................................................99 The Vanguard Group.................................................................99 BlackRock...............................................................................100 Behind those Vaccines are Companies, Shareholders, Bankers........................................................................................101 Chapter 4 Algorithmic Medicine.............................................................103 Clinical Trial Service Unit.......................................................105 Chapter 5 COVID-19 Versus Law or The Medical Trade Against the People...........................................................................................109 You Must Not Do Your Own Research When It Comes To Science.........................................................................................109 Infection Fatality Rate Less than 0.20%.................................110 Get Covid And Live Longer....................................................110 Lock-down Farce Alcohol Related Deaths Rise by 20% in England During “Pandemic”........................................................111 That Fear that Didn't Happen, The Models Failed in late March, and They Failed in April, They Failed Basically.........................112 Lockdowns just Have One Consequence, that is Making Poor People a lot Poorer.......................................................................117 From Science Fiction to Science Farce...................................118 Weaponized Viruses................................................................118 Developing Medical Counter Measures for Coronaviruses 2016..............................................................................................119 Secret Pandemic Plan to Deny Care to Elderly 2016..............119 A Scenario to Facilitate Medical Countermeasure Communication 2017...................................................................120 If You Have To: Be Persuaded, Reminded, Pressured, Lied to, Incentivized, Coerced, Bullied, Socially Shamed, Guilt-tripped, Threatened, Punished and Criminalized.....................................121 Chapter 6 The First “Confirmed” Case of Covid-19 “Virus”..................123 The Isolation of the So-Called “Virus” Farce.........................124 Chapter 7 COVID-19 The Rule By Fear..................................................127 The CDC is Certainly Misleading...........................................128 Sweden No Lockdowns Led To Better Mental Health, Healthier Economy And Happier People.....................................................128 The Vaccine Farce...................................................................129 Those With 2 Vaccine Doses “May Still Die”.........................129 Vaccines Save Lives................................................................129 Anyone Who Is Claiming that any of this is Totally Safe is Either Confused or Lying.............................................................130 Last Summer With No Vaccines Magic..................................133 There is no FDA approved Vaccine to Prevent Covid-19.......134 NEJM Editor had Close Ties with the FDA authorisation process when publishing Covid-19 Vaccine Trials......................137 Social Distancing and Face Masks Forever.............................138 Covid-19 is not a Health Pandemic, it is an Ideological Pandemic......................................................................................138 Neil Ferguson..........................................................................138 Covid-19 as a Dangerous and Deadly Disease Needs to Change.........................................................................................139 The Goal of Developing and Delivering a Universal Influenza Vaccine.........................................................................................140 Chapter 8 Universal Basic Income Program............................................141 Wales to Launch Universal Basic Income Scheme.................141 Global Over-Population Is The Real Issue..............................142 But Baby Number 7 on the Way..............................................142 Global Health Emergency.......................................................142 Lockdown Every Two Years...................................................143 Bill Bowtell.............................................................................144 Matt Hancock, Secretary of State for Health..........................145 Chapter 9 States Ban Vaccine Passports..................................................149 World Health Organization (WHO)........................................150 The Vaccine Is Trust First Trust In science.............................151 The Patients Who Die, After and Possibly From a Vaccination...................................................................................151 The Data Support The Failure of the Vaccine.........................152 I Refuse to be Vaccinated........................................................154 Manipulation Without Shame or Dignity................................155 Number of People Died Within 21 Days of Having COVID-19 Vaccine in England Between January and June 2021..................156 Pharmacovigilance Investigation Concerning Janssen Covid-19 Vaccine.........................................................................156 If It Works Perfectly is Going to Take a Decade.....................157 Chapter 10 Every Year People Catch The Flu...........................................160 Is Just Like the Common Flu..................................................161 Flu Season Didn’t Happen Last Year in Canada.....................163 Australia Is Currently Reporting “Historically Low Levels” of Influenza..................................................................................163 Two-in-One Vaccine Booster Shot that Protects Against Both Covid-19 and the Seasonal Flu....................................................164 Australia Deaths Due to Influenza 2017.................................165 Australia Deaths Due to “Covid-19” 2020-2021....................166 Covid Will Eventually Become Like the Common cold.........167 Least We Forget The Medical Trade HIV (AIDS) Virus Pandemic......................................................................................168 Influenza Vaccine A Failed Vaccine........................................171 How to Treat Yourself Coronavirus (COVID-19) at Home, Just Like the Flu...........................................................................172 Chapter 11 The Muddy Foundations, or a Sand Castle Called “Genetic Medicine”.....................................................................................173 Medical Trade so-called “Gene Therapies” + “Viruses” Farce.............................................................................................174 National Institutes of Health (NIH).........................................175 The Final Words......................................................................176 Annex 1. Letter to Sir Simon Stevens, CEO of the NHS England 2. SAGE COVID-19 Register of Participants' Interests - GOV.UK Index 179
Development Of Vaccines
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Author : Manmohan Singh
language : en
Publisher: John Wiley & Sons
Release Date : 2011-10-11
Development Of Vaccines written by Manmohan Singh and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-11 with Medical categories.
Development of Vaccines: From Discovery to Clinical Testing outlines the critical steps, and analytical tools and techniques, needed to take a vaccine from discovery through a successful clinical trial. Contributions from leading experts in the critical areas of vaccine expression, purification, formulation, pre-clinical testing and regulatory submissions make this book an authoritative collection of issues, challenges and solutions for progressing a biologic drug formulation from its early stage of discovery into its final clinical testing. A section with details and real-life experiences of toxicology testing and regulatory filing for vaccines is also included.
Assessing Vaccine Effects On Infectiousness In Covid 19 Vaccine Trials
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Author : John Hocter
language : en
Publisher:
Release Date : 2021
Assessing Vaccine Effects On Infectiousness In Covid 19 Vaccine Trials written by John Hocter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Vaccines have played an important role in the public health response to the COVID-19 pandemic. Clinical trials for several candidate vaccines demonstrated high efficacy at pre- venting severe / symptomatic disease. These vaccines have helped lower the burden of disease in the countries where they have been widely distributed (e.g., United States). The next generation of COVID-19 vaccine trials are designed to evaluate other vaccine effects (e.g., ef- ficacy against infection). Understanding and quantifying how vaccines affect infectiousness is important for making sound public health policy, and analyzing such effects in a clinical trial requires selecting an appropriate endpoint and vaccine efficacy parameter. Many analyses of vaccine effects on infectiousness condition on infection (e.g., comparing infected vacci- nated people to infected unvaccinated people), but conditional analyses have shortcomings. Most glaringly, they can lack power when efficacy against infection is high and may suffer from post-randomization selection bias. An alternative approach is to explore endpoints and vaccine efficacy parameters that do not condition on infection (i.e., unconditional analyses).In this thesis, we define and discuss multiple methods for unconditional analyses of vaccine effects on infectiousness. As these methods commonly rely on proxies of infectiousness rather than directly observed secondary transmission, we also discuss several infectiousness proxies derived from measures of viral shedding. Finally, we use simulations to demonstrate the operating characteristics of a number of these methods and infectiousness proxies in a clinical trial whose design is based on an ongoing COVID-19 vaccine trial.
Vaccine Roundup
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Author : Ian Usher
language : en
Publisher:
Release Date : 2021-03
Vaccine Roundup written by Ian Usher and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03 with categories.
Do you believe "the narrative" about COVID-19? A virus, pandemic, tests, cases, hospitalizations and deaths. Something must be done... Lockdowns, curfews, business closures, stimulus payments, furloughs, border restrictions. The only way out... Vaccines The original estimate often given for producing a vaccine in record time was "12 to 18 months". Vaccines usually take at least 5 years to go through all the processes necessary to prove safety and efficacy. Yet less than a year since the viral outbreak was declared a pandemic millions had already been given the jab. None of the vaccines have been approved, but are being used under Emergency Use Authorizations only. They are still classed as experimental, and if you are given one, you are part of the biggest vaccine trial ever run on the human race. Despite this hasty experimental roll-out, there is a huge publicity campaign underway to encourage everyone to get vaccinated as soon as possible. The pressure is on. The Great Vaccine Roundup of 2021 Do you have questions? Are you concerned? Does something feel "not quite right" about all of this? This book doesn't claim to know "the truth", nor does it suggest that the most lurid conspiracy theories are correct. What it aims to do is help you to think through all that is going on around the world, by questioning the narrative we are being fed every day. Who is involved, what motivations might they have, why is this all happening so quickly? This is an exercise in critical thinking, because only by doing this can we come to a rational and considered decision about what the best course of action is for our own personal and unique circumstances.
The Hpv Vaccine On Trial
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Author : Mary Holland
language : en
Publisher: Simon and Schuster
Release Date : 2018-09-25
The Hpv Vaccine On Trial written by Mary Holland and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-25 with Medical categories.
A Groundbreaking Guide to the HPV Vaccine and the Science, Safety, and Business Behind It Cancer strikes fear in people’s hearts around globe. So the appearance of a vaccine to prevent cancer–as we are assured the human papillomavirus (HPV) vaccine will–seemed like a game-changer. Since 2006, over eighty countries have approved the vaccine, with glowing endorsements from the world’s foremost medical authorities. Bringing in over $2.5 billion in annual sales, the HPV vaccine is a pharmaceutical juggernaut. Yet scandal now engulfs it worldwide. The HPV Vaccine on Trial is a shocking tale, chronicling the global efforts to sell and compel this alleged miracle. The book opens with the vaccine’s invention, winds through its regulatory labyrinths, details the crushing denial and dismissal of reported harms and deaths, and uncovers the enormous profits pharma and inventors have reaped. Authors Holland, Mack Rosenberg, and Iorio drill down into the clinical trial data, government approvals, advertising, and personal accounts of egregious injuries that have followed in countries as far-flung as Japan, Australia, Colombia, India, Ireland, the U.K. and Denmark. The authors have written an unprecedented exposé about this vaunted vaccine. Written in plain language, the book is for everyone concerned – parents, patients, doctors, nurses, scientists, healthcare organizations, government officials, and schools. Ultimately, this book is not just about the HPV vaccine, but about how industry, government, and medical authorities may be putting the world’s children in harm’s way.
Trial By Fury
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Author : Aaron E. Klein
language : en
Publisher:
Release Date : 1972
Trial By Fury written by Aaron E. Klein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with Medical categories.
The Niakhar High Titer Measles Vaccine Trial 1987 1990
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Author : Michel Garenne
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2020-04-30
The Niakhar High Titer Measles Vaccine Trial 1987 1990 written by Michel Garenne and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-30 with Medical categories.
This study reports the methodology and findings of a randomized controlled vaccine trial conducted in Senegal in 1987-1990. Two high-titer measles vaccines of different strains (Edmonston-Zagreb and Schwarz) were compared with a standard vaccine (the Schwarz strain) among infants aged 5 to 10 months. Comparison focused on clinical efficacy, immunogenicity and safety. Although both high-titer vaccines induced an immunogenic response even when given at the age of 5 months, they induced a lower level of antibodies, had more vaccine failures, and were not safe, inducing an excess mortality within two years after vaccination. Scientific, ethical and political issues linked with such negative findings are discussed in this book.
The Vaccine Book
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Author : Barry R. Bloom
language : en
Publisher: Academic Press
Release Date : 2016-06-23
The Vaccine Book written by Barry R. Bloom and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-23 with Medical categories.
The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy