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Vascular Innervation And Receptor Mechanisms


Vascular Innervation And Receptor Mechanisms
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Vascular Innervation And Receptor Mechanisms


Vascular Innervation And Receptor Mechanisms
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Author : Rolf Uddman
language : en
Publisher: Academic Press
Release Date : 2012-12-02

Vascular Innervation And Receptor Mechanisms written by Rolf Uddman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.


Vascular Innervation and Receptor Mechanisms: New Perspectives reviews the areas of structure, function, and pathophysiology of the circulatory system. The text focuses on the role of neuropeptides and structural function of endothelium. The book begins with a brief discussion on the background of autonomic and sensory nerves in the circulatory system, which is provided in Chapter 1. Having established the basic studies in the circulatory system, the book moves to the discussion on the analysis of peptidergic innervations and peptides in vascular control in various disorders. The last part of the book features the clinical applications of neuropeptides, perivascular peptides, and vasoactive peptides in different diseases and regulation, such as cardiovascular regulation, hypertension, congestive heart failure, and migraine and cluster headache. The text will be a good reference to both students and professionals in the fields of biology, chemistry, and medicine.



Vascular Neuroeffector Mechanisms


Vascular Neuroeffector Mechanisms
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Author : John A. Bevan
language : en
Publisher: IRL Press
Release Date : 1988

Vascular Neuroeffector Mechanisms written by John A. Bevan and has been published by IRL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.


This book is essential reading for all basic or clinical researchers who are interested in the neuronal control of vascular function. It continues the authoritative series of symposia on vascular neuroeffector mechanisms which are held every three years as an official satellite of the International Congress of Pharmacology. This latest volume, the sixth in the series, derives from a meeting held in Australia, August 30-September 2, 1987. The contributions collected here describe and disseminate some of the most recent discoveries on vascular neuroeffector transmission. Written by leading scientists in the field, they reflect substantial increases in our knowledge of neurohumoral transmission processes in general, and about vascular neuroeffector transmission in particular.



Neurogenic Mechanisms In The Cerebro Vascular Bed


Neurogenic Mechanisms In The Cerebro Vascular Bed
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Author : Lars Edvinsson
language : sv
Publisher:
Release Date : 1975

Neurogenic Mechanisms In The Cerebro Vascular Bed written by Lars Edvinsson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with categories.




The Cerebral Circulation


The Cerebral Circulation
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Author : Marilyn J. Cipolla
language : en
Publisher: Biota Publishing
Release Date : 2016-07-28

The Cerebral Circulation written by Marilyn J. Cipolla and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-28 with Medical categories.


This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.



Abc Of Hypertension


Abc Of Hypertension
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Author : D. Gareth Beevers
language : en
Publisher: John Wiley & Sons
Release Date : 2010-07-15

Abc Of Hypertension written by D. Gareth Beevers and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-15 with Medical categories.


Hypertension is a condition which affects millions of peopleworldwide and its treatment greatly reduces the risk of strokes andheart attacks. This fully revised and updated edition of the ABCof Hypertension is an established guide providing all thenon-specialist needs to know about the measurement of bloodpressure and the investigation and management of hypertensivepatients. This new edition provides comprehensively updated andrevised information on how and whom to treat. The ABC of Hypertension will prove invaluable to generalpractitioners who may be screening large numbers of patients forhypertension, as well as nurse practitioners, midwives and otherhealthcare professionals.



Regulation Of Coronary Blood Flow


Regulation Of Coronary Blood Flow
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Author : Michitoshi Inoue
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09

Regulation Of Coronary Blood Flow written by Michitoshi Inoue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.


Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.



Regulation Of Tissue Oxygenation Second Edition


Regulation Of Tissue Oxygenation Second Edition
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Author : Roland N. Pittman
language : en
Publisher: Biota Publishing
Release Date : 2016-08-18

Regulation Of Tissue Oxygenation Second Edition written by Roland N. Pittman and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-18 with Medical categories.


This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.



Control Of The Cardiovascular And Respiratory Systems In Health And Disease


Control Of The Cardiovascular And Respiratory Systems In Health And Disease
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Author : C. Tissa Kappagoda
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Control Of The Cardiovascular And Respiratory Systems In Health And Disease written by C. Tissa Kappagoda and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


On April 8-9, 1994, a symposium entitled Control of the Cardiovascular and Respiratory Systems in Health and Disease was held at the University of California Davis Medical Center in Sacramento. The purpose of this symposium was to honor the careers of Professors Hazel M. and John C. G. Coleridge. Participants in this symposium came from throughout the world. Their attendance at the symposium was a symbol of great respect and affection for the honorees. The Professors Coleridge have made many important contribu tions to the scientific literature concerning neural control of the cardiovascular and respira tory systems. In addition, they have made remarkable contributions to the lives of other scientists working in this field of investigation. Some of us have known them as mentors, counselors, friends, and supervisors; others have known them as co-investigators. Most importantly, all of us have known them as friends. This book, which contains the proceedings of the symposium, is dedicated to Hazel and John Coleridge. C. T. Kappagoda M. P. Kaufman v ACKNOWLEDGMENTS We wish to acknowledge the financial support of the following agencies for making this symposium a reality: • Astra Merck Group (Tarek Ackad, M. D. , Ph. D. ) • Boehringer Ingelheim Pharmaceuticals, Inc. (Ms. Kathryn B. Lucas and Mr. Allan Holloway) • Bristol-Myers Squibb (David L. Cram, Jr. , Pharm. D. ) • Marion/Merrrell Dow, Inc. (Mr. Brian Scheffield) • Merck and Company (Mr. Johnathan Sakakibara) • Pfizer Laboratories (Mr.



The Endothelium


The Endothelium
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Author : Michel Félétou
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2011

The Endothelium written by Michel Félétou and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.


The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References



The Esc Textbook Of Vascular Biology


The Esc Textbook Of Vascular Biology
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Author : Rob Krams
language : en
Publisher: Oxford University Press
Release Date : 2017

The Esc Textbook Of Vascular Biology written by Rob Krams and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Medical categories.


The ESC Textbook of Vascular Biology is a rich and clearly laid-out guide by leading European scientists providing comprehensive information on vascular physiology, disease, and research.