Accenting Lipid Peroxidation
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Accenting Lipid Peroxidation
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Author : Pınar Atukeren
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-12-08
Accenting Lipid Peroxidation written by Pınar Atukeren and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-08 with Science categories.
Lipid peroxidation can occur via either enzymatic or nonenzymatic reactions due to excess production of free radical molecules. This process culminates in cellular damage causing various diseases. This book examines lipid peroxidation as a current and future biomarker of oxidative stress.
Lipid Peroxidation
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Author : Angel Catalá
language : en
Publisher: Nova Science Publishers
Release Date : 2017
Lipid Peroxidation written by Angel Catalá and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Science categories.
This book presents an overview of lipid peroxidation: inhibition, effects and mechanisms. The topics analyzed, cover a broad spectrum of functions played by lipid peroxidation and presents new information in this area of research. The topics analyzed include: progress in the knowledge of lipid peroxidation, from the first evidences issued by Nicolas Theodore de Saussure in Paris 1804; fighting against lipid peroxidation: the unique story of docosahexaenoic acid in the brain; protective effects of melatonin and structurally-related molecules in reducing membrane rigidity due to lipid peroxidation; synergistic effects of antioxidant compositions during inhibited lipid autoxidation; lipid peroxidation and animal longevity; free radicals in health and disease; lipid peroxidation in autoimmune diseases; aldehydes derived from lipid peroxidation in cancer and autoimmunity; the role of reactive oxygen species and lipid peroxidation in the neurodegenerative process after spinal cord injury; kinetics and mechanisms of inhibited lipid autoxidation in presence of 4-substituted-coumarins; hypoxia and oxidative stress: cell signaling mechanisms and protective role of vitamin C and cilnidipine; characterization of oxidative stress and antioxidant potency; paying attention to time and location; lipid peroxidation in aquatic organisms: ontogenetic, phylogenetic and ecological aspects; chemistry of lipid oxidation in edible oils; and menopause progression and oxidative stress: associated mechanisms and the importance of physical exercise.
Reactive Oxygen Species Lipid Peroxidation And Protein Oxidation
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Author : Angel Catalá
language : en
Publisher: Nova Science Publishers
Release Date : 2014
Reactive Oxygen Species Lipid Peroxidation And Protein Oxidation written by Angel Catalá and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Active oxygen categories.
Many studies have shown that free radical damage and lipid peroxidation increase as a function of the degree of unsaturation of the fatty acids present in the phospholipids of biological membranes. Membrane phospholipids are particularly susceptible to oxidation not only because of their highly polyunsaturated fatty acid content but also because of their association in the cell membrane with non-enzymatic and enzymatic systems capable of generating pro-oxidative-free radical species. There are two broad outcomes to lipid peroxidation: structural damage to membranes and generation of secondary products. Membrane damage derives from the generation of fragmented fatty acyl chains, lipidlipid cross-links, lipidprotein cross-links and endocyclisation to produce isoprostanes and neuroprostanes. These processes combine to produce changes in the biophysical properties of membranes that can have profound effects on the activity of membrane-bound proteins. The consequence of peroxidation of unsaturated fatty acids is severe: damage of membranes function, enzymatic inactivation, toxic effects on the cellular division, etc. This new book presents and discusses current research on oxidative stress, and lipid oxidation non-inhibited and inhibited; assessment of oxidative balance in the lipo- and hydro-philic cellular environment in biological systems; mass spectrometry detection of protein modification by cross-reaction with lipid peroxidation products; diagonal gel electrophoretic analysis of protein disulfides: principles and applications. Other chapters describe: heavy metals exposure and cells oxidative damage; biodegradation of metallic biomaterials: its relation with the generation of reactive oxygen species; Oxidative modifications of proteins in the aging heart; role of reactive oxygen species as signalling molecules involved in the regulation of physiological processes of the nervous system; oxidative stress in diabetes and hypertension treated with alternative therapy of medicinal plants; impairment of redox homeostasis of tissue damage in inborn errors of metabolism with intoxication: insights from human and animal studies and finally lipid peroxidation of phospholipids in the vertebrate retina or in liposomes made of retinal lipids: similarities and differences are described.
Lipid Peroxidation In Biological Systems
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Author : Alex Sevanian
language : en
Publisher: The American Oil Chemists Society
Release Date : 1988
Lipid Peroxidation In Biological Systems written by Alex Sevanian and has been published by The American Oil Chemists Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
Membrane Lipid Oxidation
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Author : Carmen Vigo-Pelfrey
language : en
Publisher: CRC-Press
Release Date : 1990-11-26
Membrane Lipid Oxidation written by Carmen Vigo-Pelfrey and has been published by CRC-Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-26 with Science categories.
This two-volume text compiles the efforts of distinguished scientists nd focuses on the formation of free radicals, toxic effects of lipoperoxides, biological antioxidant protection against lipid peroxidation damage, and pathological implications of lipid peroxidation. This review also addresses vitamin E deficiency, carbon tetrachloride and ethanol poisoning, radiation damage, hyperbaric effects, tumors, aging, diabetes, liver degeneration, DNA damage, lipoprotein modification and artherosclerosis, multiple sclerosis, angiopathy, Parkinson's disease, lupus, and many other degenerative diseases. It is an excellent resource for biological chemist, cell biologists, and all who are interested in the pharmaceutical sciences.
Lipid Peroxides In Biology And Medicine
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Author : Kunio Yagi
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Lipid Peroxides In Biology And Medicine written by Kunio Yagi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Lipid Peroxides in Biology and Medicine emphasizes the importance of the control of lipid peroxides in the body for the prevention and treatment of degenerative diseases. This book discusses the production of free radicals in vivo from the action of xenobiotics, and comparative aspects of several model lipid peroxidation systems. The lipid peroxidation and membrane alterations in erythrocyte survival, and lipid peroxidations of cholesterol are also deliberated. This text likewise covers the mechanism of protection against membrane peroxidation, lipid peroxides as a cause of vascular diseases, and peroxide-mediated metabolic activation of carcinogens. Other topics include lipid peroxide in aging process and production of ethane and pentane during lipid peroxidation. This publication is valuable to biologists, medical practitioners, and clinicians researching on lipid peroxides.
Hne And Further Lipid Peroxidation Products
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Author : Werner Siems
language : en
Publisher: IOS Press
Release Date : 2005
Hne And Further Lipid Peroxidation Products written by Werner Siems and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Focuses on products of lipid peroxidation used as biomarkers of oxidative stress. This book covers the entire field of HNE research, including subjects as Cell Cycle and Proteolysis, LPO Products, Antioxidants and Detoxification, Neurodegeneration and Aging, Lipid Peroxidation, HNE and Gene Regulation, Clinical Applications and HNE, and more.
Lipid Peroxidation Research
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Author : Mahmoud Ahmed Mansour
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-01-22
Lipid Peroxidation Research written by Mahmoud Ahmed Mansour and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-22 with Science categories.
Lipid peroxidation is the major molecular mechanism that induces oxidative damage to cell structures and is also involved in the toxicity process that leads to cell death.Lipid peroxidation is a chain reaction initiated by the hydrogen abstraction or addition of an oxygen radical, resulting in the oxidative damage of polyunsaturated fatty acids (PUFA). PUFAs are more sensitive than saturated fatty acids because of the presence of a double bond adjacent to a methylene group that makes the methylene C-H bond weaker and therefore the hydrogen is more susceptible to abstraction. This leaves an unpaired electron on the carbon, forming a carbon-centered radical, which is stabilized by a molecular rearrangement of the double bonds to form a conjugated diene, which then combines with oxygen to form a peroxy-radical.In pathological situations the reactive oxygen and nitrogen species are generated at higher than normal rates, and as a consequence, lipid peroxidation occurs with deficiency of endogenous antioxidants as alpha-tocopherol deficiency or reduced glutathione. In addition to containing high concentrations of PUFAs and transition metals, biological membranes of cells and organelles are constantly being subjected to various types of damage.This book presents systematic and comprehensive reviews on free radicals and their involvement in lipid peroxidation with special emphasis on their important role in different diseases.
Lipid Peroxidation In Biomembranes
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Author : Valerian E. Kagan
language : en
Publisher: CRC Press
Release Date : 2018-01-18
Lipid Peroxidation In Biomembranes written by Valerian E. Kagan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.
This book will explain the colossal potential of life to cope with different living environments is possible owing to the exceptionally well developed mechanisms of adaptation to environmental conditions. There is an innumerable variety of concrete mechanisms which make it possible for living creatures to adapt to different and changing environmental conditions. Nevertheless, all this variety is the manifestation of the three strategic line of the adaptation process: 1. Evolutional or genotypic adaptation. 2. Phenotypic adaptation. 3. Rapid adaptation.
Lipid Oxidation Pathways
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Author : Afaf Kamal-Eldin
language : en
Publisher: AOCS Publishing
Release Date : 2003-08-30
Lipid Oxidation Pathways written by Afaf Kamal-Eldin and has been published by AOCS Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-30 with Science categories.
Autoxidation of unsaturated lipids has received much attention because it has many applications in the rancidity of foods and stability of lipids in biological tissues and compartments. This book reviews state-of-the-art developments in the understanding of the oxidation of lipids and its connection with the oxidation of other biological molecules such as proteins and starch. The various chapters illustrate the special features associated with different lipids, antioxidants, reaction conditions, and lipids environments. The material in this book provides a better understanding of lipid oxidation pathways.