Advances In Chromatographic Techniques For Therapeutic Drug Monitoring
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Advances In Chromatographic Techniques For Therapeutic Drug Monitoring
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Author : Amitava Dasgupta
language : en
Publisher: CRC Press
Release Date : 2009-10-06
Advances In Chromatographic Techniques For Therapeutic Drug Monitoring written by Amitava Dasgupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-06 with Medical categories.
For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for imp
Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology
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Author : Seth Kwabena Amponsah
language : en
Publisher: Springer Nature
Release Date : 2022-10-25
Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology written by Seth Kwabena Amponsah and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-25 with Medical categories.
This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges
Therapeutic Drug Monitoring And Toxicology By Liquid Chromatography
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Author : Steven H.Y. Wong
language : en
Publisher: Routledge
Release Date : 2017-09-19
Therapeutic Drug Monitoring And Toxicology By Liquid Chromatography written by Steven H.Y. Wong and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-19 with Medical categories.
This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.
Recent Developments In Therapeutic Drug Monitoring And Clinical Toxicology
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Author : Irving Sunshine
language : en
Publisher: CRC Press
Release Date : 2023-06-14
Recent Developments In Therapeutic Drug Monitoring And Clinical Toxicology written by Irving Sunshine and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-14 with Medical categories.
Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr
Drug Monitoring By Hplc
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Author : Victoria Samanidou
language : en
Publisher: Nova Science Publishers
Release Date : 2010
Drug Monitoring By Hplc written by Victoria Samanidou and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Drug monitoring categories.
Recently HPLC-MS/MS has gained increasing popularity in clinical laboratories due to the advantages of the technology over other methods, while the capital cost for instruments has been decreased. HPLC-MS/MS provides high specificity and sensitivity for the simultaneous measurement of several drugs and/or their major metabolites in one single analytical run. In this new book chromatographic methods published in the last decade are reviewed regarding their applicability to drug monitoring. HPLC methods for anti-cancer drugs, bronchodilators, cardiovascular drugs, antipsychotics, antibiotics, antiepileptic drugs, antidepressants, and immunosuppressants have been presented comprehensively regarding sample preparation and chromatographic separation. Supportive information has been included on HPLC analysis and sample preparation.
Analytical Methods For Therapeutic Drug Monitoring And Toxicology
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Author : Q. Alan Xu
language : en
Publisher: John Wiley & Sons
Release Date : 2011-04-12
Analytical Methods For Therapeutic Drug Monitoring And Toxicology written by Q. Alan Xu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-12 with Science categories.
This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatography (UPLC) coupled with UV (UPLC-UV) detection and mass spectrometry (UPLC-MS/MS). With more detailed and complete summaries than sketchy and abbreviated formats used in the other books, this book provides a thorough description of method validation and results, as well as the operating parameters.
Recent Developments In Therapeutic Drug Monitoring And Clinical Toxicology
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Author : Irving Sunshine
language : en
Publisher:
Release Date : 2008
Recent Developments In Therapeutic Drug Monitoring And Clinical Toxicology written by Irving Sunshine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with MEDICAL categories.
Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr
Handbook Of Analytical Therapeutic Drug Monitoring And Toxicology 1996
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Author : Steven H.Y. Wong
language : en
Publisher: CRC Press
Release Date : 2017-11-22
Handbook Of Analytical Therapeutic Drug Monitoring And Toxicology 1996 written by Steven H.Y. Wong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Medical categories.
Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.
Therapeutic Drug Monitoring
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Author : Amitava Dasgupta
language : en
Publisher: Elsevier
Release Date : 2024-04-26
Therapeutic Drug Monitoring written by Amitava Dasgupta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-26 with Medical categories.
Therapeutic Drug Monitoring 2nd Edition is an updated reference on TDM analytical techniques in diverse clinical settings. This new edition reviews the exciting new developments in the area, including seven new chapters covering immunoassay design and applications, combined chromatographic techniques in therapeutic monitoring, drug monitoring in alternative specimens, pharmacogenomics of anticancer drugs, pharmacogenomics testing for patient management, selected antifungal agents, pharmacodynamic monitoring, and therapeutic drug monitoring of selected anticoagulants. All remaining chapters in the first edition were thoroughly revised and updated. Therapeutic Drug Monitoring 2nd Edition is the ideal reference for clinical pathologists, pharmacologists, and toxicologists involved with TDM. Scientists working in diagnostic companies, developing reagents for monitoring therapeutic drugs will also find relevant information in this book. Includes new chapters covering antifungal, anticoagulant, and anticancer drugs monitoring Discusses limitations of current immunoassays, new and sophisticated chromatographic techniques, the clinical effectiveness of newer antiretroviral agents, anticonvulsants and antidepressants Provides full coverage of pharmacogenomics and personalized medicine, principles of pharmacokinetics and pharmacodynamics, and the application of biomarkers in TDM
Advances In Chromatography
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Author : J. Calvin Giddings
language : en
Publisher: CRC Press
Release Date : 2021-06-24
Advances In Chromatography written by J. Calvin Giddings and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-24 with Science categories.
This book provides the most up-to-date information on a wide range of developments in chromatographic methods and applications. It presents timely, cutting-edge reviews in the fields of bio-, analytical, organic, polymer, and pharmaceutical chemistry.
