Advances In Dna Sequence Specific Agents Volume 4
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Advances In Dna Sequence Specific Agents
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Author : B.J. Chapman
language : en
Publisher: Elsevier
Release Date : 2002-09-17
Advances In Dna Sequence Specific Agents written by B.J. Chapman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-17 with Science categories.
This series encompasses design, synthesis, application, and analytical methods (including clinical and in vitro) for the study of these critical interactions. As our understanding of the genome and proteome expands, general developments in the field of DNA sequence specific interaction are likely to play an increasingly important role. Accordingly, manuscripts have been solicited from experts covering a diverse range of fields, reflecting the cross-disciplinary and dynamic nature of the series.Volume 4 describes work on the modification of DNA by AT specific anticancer drugs, DNA alkylation events which involve metabolite generation, DNA sequence recognition by two selective binders, bulged DNA microenvironments as molecular targets, DNA sequence specific binding by short peptides and the analysis of DNA-protein interactions using DNase I footprinting methodology.Features include:• Expert contributors from the Biomedical world• Emerging areas of drug design and therapeutic applications• Nucleic acid-protein interactions• Color graphics of molecular modeling analyses• New and emerging methodologies
Advances In Dna Sequence Specific Agents
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Author : J.B. Chaires
language : en
Publisher: Elsevier
Release Date : 1996-07-09
Advances In Dna Sequence Specific Agents written by J.B. Chaires and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-09 with Science categories.
DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molecular interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of Advances in DNA Sequence Specific Agents. As was the case for Volume 1, Part A also covers methodology, but in Volume 2 we include calorimetric titrations, molecular modeling, X-ray crystallographic and NMR structural studies, and transcriptional assays. Part B also follows the same format as Volume 1 and describes the sequence specificities and covalent and noncovalent interactions of small ligands with DNA.This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition.
Advances In Dna Sequence Specific Agents Volume 4
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Author : Chapman B. Jones
language : en
Publisher:
Release Date : 2002
Advances In Dna Sequence Specific Agents Volume 4 written by Chapman B. Jones and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
Advanced Ceramics And Applications
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Author : Rainer Gadow
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2021-10-04
Advanced Ceramics And Applications written by Rainer Gadow and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-04 with Technology & Engineering categories.
New ceramic materials are highly appreciated due to their manifold features including mechanical properties, environmental uses, energy applications and many more. This work presents the latest research development and covers a broad range of topics from stabilized zirconia ceramics with enhanced functional properties to ceramic components in medical/biological applications.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1993
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.
Energetics Of Biological Macromolecules Part C
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Author :
language : en
Publisher: Elsevier
Release Date : 2000-08-09
Energetics Of Biological Macromolecules Part C written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-08-09 with Science categories.
Volume 323 of Methods in Enzymology is dedicated to the energetics of biological macromolecules. Understanding the molecular mechanisms underlying a biological process requires detailed knowledge of the structural relationships within the system and an equally detailed understanding of the energetic driving forces that control the structural interactions. This volume presents modern thermodynamic techniques currently being utilized to study the energetic driving forces in biological systems. It will be a useful reference source and textbook for scientists and students whose goal is to understand the energetic relationships between macromoleculer structures and biological functions. This volume supplements Volumes 259 and Volume 295 of Methods in Enzymology.Key Features* Probing Stability of Helical Transmembrane Proteins* Energetics of Vinca Alkaloid Interactions with Tubulin* Deriving Complex Ligand Binding Formulas* Mathematical Modeling of Cooperative Interactions in Hemoglobin* Analysis of Interactions of Regulatory Protein TyrR with DNA* Parsing Free Energy of Drug-DNA Interactions* Use of Fluorescence as Thermodynamics Tool
National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1985
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Medicine categories.
Metallopharmaceuticals I
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Author : Michael J. Clarke
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Metallopharmaceuticals I written by Michael J. Clarke and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Science categories.
Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of high current interest written by leading international experts.
Recent Advances In Polyphenol Research Volume 4
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Author : Annalisa Romani
language : en
Publisher: John Wiley & Sons
Release Date : 2014-10-20
Recent Advances In Polyphenol Research Volume 4 written by Annalisa Romani and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-20 with Science categories.
Plant polyphenols are secondary metabolites that constitute one of the most common and widespread groups of natural products. They express a large and diverse panel of biological activities including beneficial effects on both plants and humans. Many polyphenols, from their structurally simplest representatives to their oligo/polymeric versions (also referred to as vegetable tannins) are notably known as phytoestrogens, plant pigments, potent antioxidants, and protein interacting agents. Sponsored by the scholarly society Groupe Polyphénols, this publication, which is the fourth volume in this highly regarded Recent Advances in Polyphenol Research series, is edited by Annalisa Romani, Vincenzo Lattanzio, and Stéphane Quideau. They have once again, like their predecessors, put together an impressive collection of cutting-edge chapters written by expert scientists, internationally respected in their respective field of polyphenol sciences. This Volume 4 highlights some of the latest information and opinion on the following major research topics about polyphenols: Biosynthesis and genetic manipulation Ecological role of polyphenols in plant defense Actions of polyphenols in human health protection Physical organic chemistry and organic synthesis Chemists, biochemists, plant scientists, pharmacognosists and pharmacologists, biologists, ecologists, food scientists and nutritionists will all find this book an invaluable resource. Libraries in all universities and research institutions where these disciplines are studied and taught should have copies on their bookshelves.
Bibliographies And Literature Of Agriculture
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Author :
language : en
Publisher:
Release Date : 1978
Bibliographies And Literature Of Agriculture written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Agriculture categories.