Advances In The Immunopathogenesis Of Multiple Sclerosis
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Advances In The Immunopathogenesis Of Multiple Sclerosis
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Author : Domencio Gambi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Advances In The Immunopathogenesis Of Multiple Sclerosis written by Domencio Gambi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
P.A. MURARO, A. LUGARESI, D. GAMBI Many of the pathological aspects of multiple sclerosis (MS) lesions have been known for over a century. It is only recently, however, that different patterns of demyelination have been linked to distinct pathways of immune-mediated tissue destruction. In particular, the inter-individual heterogeneity of MS lesions has suggested that different mechanisms may act in different patients, accounting for the variability observed in clinical course, immunological findings in peripheral blood and cere brospinal fluid (CSF), and response to immunomodulatory treatments. To provide an overview of the basic mechanisms possibly involved in MS lesion initiation and development, an international meeting was organized in the context of the annual Congress of the Italian Neuroimmunology Association (AINI), held at the University of Chieti, in Chieti Italy on 29 October 1998. The high standard of presentations prompted us to report them in extended form, to highlight recent pro gress in the understanding of basic mechanisms sustaining MS immuno pathogenesis. A central role in the possible mechanisms leading to myelin destruc tion has been attributed to T lymphocytes reactive to myelin antigens. Studies on the myelin antigen-specific T cell repertoire have contributed significant advances to our knowledge of autoimmunity (Chapters 1,2).
Advances In The Immunopathogenesis Of Multiple Sclerosis
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Author : Domencio Gambi
language : en
Publisher: Springer
Release Date : 1999
Advances In The Immunopathogenesis Of Multiple Sclerosis written by Domencio Gambi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Gardening categories.
This volume highlights recent advances in the basic mechanisms of the immunopathogenesis of multiple sclerosis. Written by scientists actively involved in leading research, it mainly focuses on aspects of autoreactive T cell activation. Progress in the field of blood-brain barrier damage pathophysiology, antigen presentation in the central nervous system and magnetic resonance imaging are also reported. Providing a rapid access to up-to-date, leading research on basic pathogenetic mechanisms of multiple sclerosis, this book is directed not only to neuroimmunologists, but also to a general neurological readership.
Reassessing The Immune System Contribution In Multiple Sclerosis Therapeutic Target Biomarkers Of Disease And Immune Pathogenesis
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Author : Maria Teresa Cencioni
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-10
Reassessing The Immune System Contribution In Multiple Sclerosis Therapeutic Target Biomarkers Of Disease And Immune Pathogenesis written by Maria Teresa Cencioni and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-10 with Medical categories.
Advances In Multiple Sclerosis Research Mdash Series I
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Author : John Matsoukas
language : en
Publisher: MDPI
Release Date : 2021-04-19
Advances In Multiple Sclerosis Research Mdash Series I written by John Matsoukas and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-19 with Science categories.
Designing immunotherapeutics, drugs, and anti-inflammatory reagents has been at the forefront of autoimmune research, in particular multiple sclerosis, for over 20 years. Delivery methods that are used to modulate effective and long-lasting immune responses have been the major focus. This Special Issue focused on delivery methods to be used for vaccines, immunotherapeutic approaches, drug design, and anti-inflammatories and their outcomes in preclinical studies and clinical trials.
Recent Advances In The Immunology Of Helminth Infection Protection Pathogenesis And Panaceas
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Author : Kara Filbey
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-03
Recent Advances In The Immunology Of Helminth Infection Protection Pathogenesis And Panaceas written by Kara Filbey and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-03 with Science categories.
Dr. Paul Giacomin is a co-founder of Paragen Bio. Dr. Siracusa is the founder and president of Nemagen Discoveries. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004
Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
La Scl Rose En Plaques Historique Pid Miologie Et Pathog Nie
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Author : Gilles Defer
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-08-27
La Scl Rose En Plaques Historique Pid Miologie Et Pathog Nie written by Gilles Defer and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-27 with Medical categories.
En France, la sclérose en plaques (SEP) touche plus de 80 000 personnes et plus de 3 000 nouveaux cas sont diagnostiqués chaque année. C'est la plus commune des maladies neurologiques de l'adulte jeune. La plupart des cas concernent une population de 20 à 40 ans, majoritairement féminine. Les manifestations neurologiques de la maladie sont secondaires à une destruction progressive des gaines de myéline qui entourent les fibres nerveuses, et dont le rôle est d'assurer leur protection et la bonne transmission de l'influx nerveux, et ceci en raison d'un dysfonctionnement du système immunitaire. La sclérose en plaques se présente sous deux formes : la forme avec poussées qui est la plus fréquente et la forme progressive où le risque de handicap est plus élevé. Les conséquences de cette affection peuvent être importantes en termes physiques et psychologiques mais aussi de vie sociale, professionnelle et familiale. Cet ouvrage pratique et synthétique, richement illustré, aborde successivement l'historique, l'épidémiologie et l'histoire naturelle puis la pathogénie de cette maladie. Il en décrit l'évolution des concepts, l'épidémiologie, l'anatomopathologie et l'immunologie et ouvre des perspectives sur les nouveaux traitements et les capacités de remyélinisation. Cet ouvrage, rédigé par un collectif d'experts biologistes et médecins travaillant dans les centres spécialisés sur la SEP, est destiné aussi bien aux neurologues confirmés souhaitant mettre à jour leurs connaissances, qu'aux autres professionnels de santé impliqués dans la prise en charge des patients et bien sûr aux médecins et paramédicaux en formation qui voudraient mieux comprendre ce que représente la sclérose en plaques.
Research Awards Index
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Author :
language : en
Publisher:
Release Date : 1985
Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Medicine categories.
Autoimmune Vasculitis Advances In Pathogenesis And Therapies
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Author : Joshua Daniel Ooi
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-23
Autoimmune Vasculitis Advances In Pathogenesis And Therapies written by Joshua Daniel Ooi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-23 with Medical categories.
Biomarkers In Autoimmune Diseases Of The Central Nervous System
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Author : Mei-Ping Ding
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-25
Biomarkers In Autoimmune Diseases Of The Central Nervous System written by Mei-Ping Ding and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-25 with Medical categories.
Autoimmune diseases of the central nervous system (CNS) are a group of complex and disabling disorders characterized by the immune system mistakenly attacking the CNS. During the last 2 decades, we have witnessed a rapidly evolving spectrum of CNS autoimmune diseases, which has become a research hotspot in neurology. These include CNS inflammatory demyelinating diseases such as multiple sclerosis and neuromyelitis optical spectrum disorders, paraneoplastic, and other autoimmune encephalomyelitis and CNS involvement in systemic autoimmune diseases. Recently, although remarkable discoveries have accumulated more understanding of the autoimmune basis behind the physiopathologic mechanism, the exact pathogenic processes are still unclear. Patients may present with a variety of manifestations, posing a great challenge to diagnosis and management. The determination of biomarkers plays a significant role in CNS autoimmune diseases. Biomarkers can reflect the presence, nature, and intensity of certain immune responses triggered by both genetic and environmental processes, and bear great importance in guiding clinical diagnosis, estimating disease risk or prognosis, evaluating disease severity, and monitoring progression or response to therapy. For instance, the detection of disease-specific antibodies can contribute to the accurate diagnosis and precise treatment. Moreover, identifying the diverse biomarkers could further help to achieve the ultimate goal of personalized medicine.