Reassessing The Immune System Contribution In Multiple Sclerosis Therapeutic Target Biomarkers Of Disease And Immune Pathogenesis
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Reassessing The Immune System Contribution In Multiple Sclerosis Therapeutic Target Biomarkers Of Disease And Immune Pathogenesis
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Author : Maria Teresa Cencioni
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-10
Reassessing The Immune System Contribution In Multiple Sclerosis Therapeutic Target Biomarkers Of Disease And Immune Pathogenesis written by Maria Teresa Cencioni and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-10 with Medical categories.
Innate Immunity And Neurodegenerative Diseases Triggers From Self And Non Self
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Author : Kiran Bhaskar
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-30
Innate Immunity And Neurodegenerative Diseases Triggers From Self And Non Self written by Kiran Bhaskar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-30 with Science categories.
Multiple Sclerosis Therapeutics
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Author : Jeffrey A. Cohen
language : en
Publisher: Cambridge University Press
Release Date : 2011-10-20
Multiple Sclerosis Therapeutics written by Jeffrey A. Cohen and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-20 with Medical categories.
This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.
Imaging The Immune Response In Inflammatory Preclinical In Vivo Models
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Author : Marco Erreni
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-17
Imaging The Immune Response In Inflammatory Preclinical In Vivo Models written by Marco Erreni and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-17 with Medical categories.
Innate Immune Responses In Cns Inflammation
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Author : Mireia Guerau-de-Arellano
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-30
Innate Immune Responses In Cns Inflammation written by Mireia Guerau-de-Arellano and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-30 with Medical categories.
A Year In Review Discussions In Autoimmune And Autoinflammatory Disorders
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Author : Raphaela Goldbach-Mansky
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-31
A Year In Review Discussions In Autoimmune And Autoinflammatory Disorders written by Raphaela Goldbach-Mansky and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-31 with Medical categories.
23 03 2024
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Author : Francisco Javier Quintana
language : en
Publisher: Elsevier
Release Date : 2024-06-11
23 03 2024 written by Francisco Javier Quintana and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-11 with Medical categories.
Mechanisms of Disease Pathogenesis in Multiple Sclerosis summarizes our current understanding on MS and its clinical features and monitoring with available biomarkers, focusing on mechanisms that drive disease pathogenesis and their control by genetic, environmental factors and novel therapies for disease management. The book is written for neurologists, neuroimmunologists and clinical, translational and basic researchers interested in mechanisms of neurodegeneration. Multiple Sclerosis (MS) is an autoimmune disease which targets the central nervous system (CNS). It is the most common cause of non-traumatic neurological disability in young adults with a prevalence of 1 in 1000 and increasing, hence the importance of this book. - Summarizes our current understanding of Multiple Sclerosis - Discusses clinical features and available biomarker monitoring - Focuses on mechanisms that drive disease pathogenesis
Molecular Basis Of Multiple Sclerosis
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Author : Roland Martin
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-14
Molecular Basis Of Multiple Sclerosis written by Roland Martin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-14 with Medical categories.
Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. Consequently, the current strategies for treatment and management of patients are limited in their efficacy. The mechanisms of tissue protection and repair are probably even less understood. One reason for these limitations is the enormous complexity of the disease and every facet of its pathogenesis, the mechanisms of tissue injury, the diagnostic procedures and finally the efficacy of treatments and their side effects. The aim of this book is to review the most recent advances made in this highly complex field.
Cellular And Molecular Mechanisms In Pathogenesis Of Multiple Sclerosis
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Author : Edwin Wan
language : en
Publisher: MDPI
Release Date : 2020-11-25
Cellular And Molecular Mechanisms In Pathogenesis Of Multiple Sclerosis written by Edwin Wan and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Science categories.
Multiple sclerosis (MS) is one of the most common neurological disorders in young adults. The etiology of MS is not known, but it is generally accepted that it is autoimmune in nature. Our knowledge of the pathogenesis of MS has increased tremendously in the past decade through clinical studies and the use of experimental autoimmune encephalomyelitis (EAE), a model that has been widely used for MS research. Major advances in the field, such as understanding the roles of pathogenic Th17 cells, myeloid cells, and B cells in MS/EAE, as well as cytokine and chemokine signaling that controls neuroinflammation, have led to the development of potential and clinically approved disease-modifying agents (DMAs). There are many aspects related to the initiation, relapse and remission, and progression of MS that are yet to be elucidated. For instance, what are the genetic and environmental risk factors that promote the initiation of MS, and how do these factors impact the immune system? What factors drive the progression of MS, and what are the roles of peripheral immune cells in disease progression? How do the CNS-infiltrated immune cells interact with the CNS-resident glial cells when the disease progresses? What is the role of microbiome in MS? Can we develop animal models that better represent subcategories of MS? Understanding the cellular and molecular mechanisms that govern the pathogenesis of MS will help to develop novel and more specific therapeutic strategies that will ultimately improve clinical outcomes of the treatments. This Special Issue of Cells has published original research articles, a retrospective clinical report, and review articles that investigate the cellular and molecular basis of MS.
Translational Neuroimmunology In Multiple Sclerosis
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Author : Ruth Arnon
language : en
Publisher: Academic Press
Release Date : 2016-05-10
Translational Neuroimmunology In Multiple Sclerosis written by Ruth Arnon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-10 with Medical categories.
Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development. - Provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis and the translation of this research to immunotherapy treatment - Edited by renowned leaders in the field of neuroimmunology and multiple sclerosis - Contains the latest resource material for basic and clinical scientists and practitioners in neuroscience, neurology, immunology, and pharmacology - 2017 BMA Medical Book Awards Highly Commended in Neurology