Alternative Testing Methodologies
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Alternative Testing Methodologies
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Author :
language : en
Publisher:
Release Date : 1998
Alternative Testing Methodologies written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
Alternative Toxicological Methods
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Author : Harry Salem
language : en
Publisher: CRC Press
Release Date : 2003-03-26
Alternative Toxicological Methods written by Harry Salem and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-26 with Medical categories.
Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist
Environmental Health Perspectives
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Author :
language : en
Publisher:
Release Date : 1993
Environmental Health Perspectives written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Environmental health categories.
Chemical Testing Using New Approach Methodologies Nams
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Author : Amy J. Clippinger
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-16
Chemical Testing Using New Approach Methodologies Nams written by Amy J. Clippinger and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-16 with Science categories.
Alternatives To Animal Testing
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Author : Hajime Kojima
language : en
Publisher: Springer
Release Date : 2018-12-27
Alternatives To Animal Testing written by Hajime Kojima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-27 with Medical categories.
This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
The History Of Alternative Test Methods In Toxicology
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Author :
language : en
Publisher: Academic Press
Release Date : 2018-10-20
The History Of Alternative Test Methods In Toxicology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-20 with Medical categories.
The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated, miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing, capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialized areas, such as inhalation toxicity studies. The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement, Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now-classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialised areas, such as inhalation toxicity studies.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1998
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medicine categories.
Annual Plan For Fiscal Year
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Author : National Toxicology Program (U.S.)
language : en
Publisher:
Release Date : 1995
Annual Plan For Fiscal Year written by National Toxicology Program (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Toxicity testing categories.
Alternative Methods For Toxicity Testing
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Author :
language : en
Publisher:
Release Date : 1986
Alternative Methods For Toxicity Testing written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Animal experimentation categories.
Assessment In The Classroom
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Author : George K. Cunningham
language : en
Publisher: Psychology Press
Release Date : 1998
Assessment In The Classroom written by George K. Cunningham and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Education categories.
Educational assessment, at one time a relatively uncontroversial subject, is now riven by a diversity of views. The most crucial division is between those who continue to believe in the effectiveness of objective assessment techniques and those who favour alternative methods. This book presents an analysis of the strengths, weaknesses and rationales for both.