Alzheimer S Disease New Insights Into Biomechanisms And Therapeutic Target
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Alzheimer S Disease New Insights Into Biomechanisms And Therapeutic Target
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Author : Wenjuan Yao
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-19
Alzheimer S Disease New Insights Into Biomechanisms And Therapeutic Target written by Wenjuan Yao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-19 with Science categories.
With the prevalence of Alzheimer's disease on the rise among aging populations, it becomes crucial to acquire a comprehensive understanding of the underlying biomechanisms to enhance preventive measures for patients. Recent advances in the elucidation of basic biomechanisms such as the major role of the influential genetic factor TREM2 in the immunological basis of Alzheimer’s disease and the establishment of mechanobiology with relevance to Alzheimer’s diseases, hold promising translational value and potential for clinical applications. This research topic aims to elucidate the most recent progress in the field of basic and clinical research. Specifically, we will focus on areas such as the pathogenesis of Alzheimer's disease, neurodegenerative processes and early changes, perception and cognition deficits, immune regulation, as well as new therapeutic targets and innovative strategies. The topic editorial team is dedicated to advancing the field of Alzheimer's disease and creating a platform which future progress can be built upon.
New Insights Into Intracellular Pathways And Therapeutic Targets In Cns Diseases
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Author : Lisa Gherardini
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-14
New Insights Into Intracellular Pathways And Therapeutic Targets In Cns Diseases written by Lisa Gherardini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-14 with Science categories.
The intracellular signalling network machinery, responding to different micro-environmental cues, regulates all aspects of cellular physiology, including metabolism, gene expression and modification, proliferation, differentiation and programmed cell death. Indeed, changes in the expression of cell surface receptors and/or their mutations, as well as ligand abundance, can have profound effects on cell physiology of the central nervous system and disarray of cell signalling often lies beneath the cause of neuronal diseases. New interesting knowledge has been recently gathered demonstrating the importance of canonical developmental pathways such as Sonic Hedgehog (SHH), Wnt/b-catenin and Notch-3 in neuronal homeostasis. As well, the role of autophagosomes generating pathways has recently been involved in conditions such as neuroinflammation, Alzheimer's and Parkinson’s diseases, brain tumours, and damages due to cerebral ischemia and reperfusion, with a specific attention on the accumulation of ROS-generating damaged mitochondria.
New Insights Into Adult Neurogenesis And Neurodegeneration Challenges For Brain Repair
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Author : Jose Angel Morales-Garcia
language : en
Publisher: Frontiers Media SA
Release Date : 2022-04-04
New Insights Into Adult Neurogenesis And Neurodegeneration Challenges For Brain Repair written by Jose Angel Morales-Garcia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-04 with Science categories.
Application Of Artificial Intelligence In Neurological Disorders
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Author : Mullaicharam Bhupathyraaj
language : en
Publisher: Springer Nature
Release Date : 2024-06-30
Application Of Artificial Intelligence In Neurological Disorders written by Mullaicharam Bhupathyraaj and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-30 with Science categories.
This book discusses the role of artificial intelligence in neurological disorders, including, alleviating movement disorders, psychiatric disorders, diagnosis of neurological and neurodegenerative disorders, dementia, neuronal cancer, neuronal Infections, and brain diseases. It explores applications of artificial intelligence in the early diagnosis, prognosis, and development of new therapies against neurodegenerative disorders. This book also provides cutting-edge research using AI for studying neuroimage analysis, toward the discovery of new biological pathways and systems implicated in dementia and related diseases. It also reviews AI-based interventions in depression research and treatment. The chapter also examines the potential benefits of using AI to help manage depression, from improved access to coordinated care. This book is an essential source for students, researchers, academicians, and neurologists aiming to understand AI-based approaches for the diagnosis, treatment, and prevention of neurological disorders.
Cerebrovascular And Neurodegenerative Diseases New Insights Into Molecular Cell Biology And Therapeutic Targets
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Author : Sikha Saha
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-30
Cerebrovascular And Neurodegenerative Diseases New Insights Into Molecular Cell Biology And Therapeutic Targets written by Sikha Saha and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-30 with categories.
New Insights And Perspectives On Traumatic Brain Injury Integration Translation And Multidisciplinary Approaches
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Author : Zhou Zhou
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-01
New Insights And Perspectives On Traumatic Brain Injury Integration Translation And Multidisciplinary Approaches written by Zhou Zhou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-01 with Medical categories.
Traumatic brain injury (TBI) remains one of healthcare's most significant challenges and policy making. TBI could not only lead to long-term functional impairment but also a decrease in quality of life. Lowering the mortality risk and benefitting survivors' living quality remains the target of neurotrauma studies globally. With the advent of novel TBI-related clinical and basic research approaches, diagnostics, therapeutics research, and novel and multidisciplinary methods have emerged. Despite promising progress, no completely effective treatment prevents or minimizes TBI and its related neurological and psychiatric sequelae. Understanding the mechanisms underlying the pathophysiology, treatment progress, and clinically based translational and engineering research on TBI may pave the way for potential treatment targets, diagnostic markers, and preventive methods that ultimately lead to efficacious therapeutic strategies. This Research Topic aims to disseminate high-quality TBI and related research, especially for the compositive and in-depth study in integration, translation, and multidisciplinary approaches in TBI research, including new technology and research methods in clinical neurology, new findings in neuroendocrinology, neuropathology and new development in neuropharmacology, neurophysiology. This Research Topic is focused on novel developments, current challenges, future perspectives, and especially interdisciplinary research in the field of TBI.
The Molecular And Genetic Basis Of Neurologic And Psychiatric Disease
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Author : Roger N. Rosenberg
language : en
Publisher: Butterworth-Heinemann
Release Date : 2003
The Molecular And Genetic Basis Of Neurologic And Psychiatric Disease written by Roger N. Rosenberg and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
Inside the third edition of this reference, the reader will find thorough and authoritative discussions of all of these developments and their implications for clinical practice. It includes a major new section on Psychiatric Diseases; descriptions of the molecular and genetic basis of the spongiform encephalopathies as well as the expression of the prion gene under physiologic and pathologic conditions; additional coverage examines the human genome project and neurologic disease; and coverage on alzheimer's disease and related dementias.
New Insights Into Understanding And Managing Nafld
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Author : Águeda González Rodríguez
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-07
New Insights Into Understanding And Managing Nafld written by Águeda González Rodríguez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-07 with Medical categories.
Cell Signaling
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Author : Adeeb Shehzad
language : en
Publisher: CRC Press
Release Date : 2025-04-17
Cell Signaling written by Adeeb Shehzad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-17 with Science categories.
This book provides a comprehensive understanding of cell signaling, molecular interactions, and their implications for human health and diseases. It introduces fundamental principles underlying cell communication through signaling molecules and their diverse transmission and reception mechanisms, highlighting their role in intercellular communication through voltage- and ion-gated channels, immunological and neuron synapses, and rhinovirus–receptor interaction involved in pathogenesis and disease development. Toward the end, the book highlights the profound implications of altered cell signaling pathways in the inflammation and immune response followed by the progression of various disorders, including cancer, endocrine disorders, and neurological illnesses. It explores the diagnostic and therapeutic implications of cell signaling in targeted therapies, highlighting advanced techniques for detecting signaling molecules and innovative therapeutic approaches to inspire new developments in precision medicine. It serves as an important resource for academics, students, and professionals in the fields of cell biology and biomedical sciences. Key Features: Provides in-depth understanding of cell signaling, exploring its complexities and impact on human health and disease Introduces fundamental principles of cell communication, emphasizing the different signaling molecules and their various transmission pathways Focuses on complex structures and functions of receptors, highlighting their essential role in intercellular communication and regulating cellular behavior Examines the molecular aspects of cell surface adhesion receptors, elucidating protein–protein interactions, signaling cascades, and enzyme–substrate interactions Discusses the impact of cell signaling on inflammation, cancer, and endocrine and neurological disorders
New Insights Into The Molecular Basis Of Long Term Plasticity Underlying Addiction And Addictive Behaviours
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Author : Elisabeth Piccart
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-29
New Insights Into The Molecular Basis Of Long Term Plasticity Underlying Addiction And Addictive Behaviours written by Elisabeth Piccart and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-29 with Science categories.