New Insights Into Intracellular Pathways And Therapeutic Targets In Cns Diseases
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New Insights Into Intracellular Pathways And Therapeutic Targets In Cns Diseases
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Author : Lisa Gherardini
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-14
New Insights Into Intracellular Pathways And Therapeutic Targets In Cns Diseases written by Lisa Gherardini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-14 with Science categories.
The intracellular signalling network machinery, responding to different micro-environmental cues, regulates all aspects of cellular physiology, including metabolism, gene expression and modification, proliferation, differentiation and programmed cell death. Indeed, changes in the expression of cell surface receptors and/or their mutations, as well as ligand abundance, can have profound effects on cell physiology of the central nervous system and disarray of cell signalling often lies beneath the cause of neuronal diseases. New interesting knowledge has been recently gathered demonstrating the importance of canonical developmental pathways such as Sonic Hedgehog (SHH), Wnt/b-catenin and Notch-3 in neuronal homeostasis. As well, the role of autophagosomes generating pathways has recently been involved in conditions such as neuroinflammation, Alzheimer's and Parkinson’s diseases, brain tumours, and damages due to cerebral ischemia and reperfusion, with a specific attention on the accumulation of ROS-generating damaged mitochondria.
Brain Hypoxia And Ischemia New Insights Into Neurodegeneration And Neuroprotection
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Author : Natalia N Nalivaeva
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-15
Brain Hypoxia And Ischemia New Insights Into Neurodegeneration And Neuroprotection written by Natalia N Nalivaeva and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-15 with categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Alzheimer S Disease New Insights Into Biomechanisms And Therapeutic Target
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Author : Wenjuan Yao
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-19
Alzheimer S Disease New Insights Into Biomechanisms And Therapeutic Target written by Wenjuan Yao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-19 with Science categories.
With the prevalence of Alzheimer's disease on the rise among aging populations, it becomes crucial to acquire a comprehensive understanding of the underlying biomechanisms to enhance preventive measures for patients. Recent advances in the elucidation of basic biomechanisms such as the major role of the influential genetic factor TREM2 in the immunological basis of Alzheimer’s disease and the establishment of mechanobiology with relevance to Alzheimer’s diseases, hold promising translational value and potential for clinical applications. This research topic aims to elucidate the most recent progress in the field of basic and clinical research. Specifically, we will focus on areas such as the pathogenesis of Alzheimer's disease, neurodegenerative processes and early changes, perception and cognition deficits, immune regulation, as well as new therapeutic targets and innovative strategies. The topic editorial team is dedicated to advancing the field of Alzheimer's disease and creating a platform which future progress can be built upon.
Novel Therapeutic Target And Drug Discovery For Neurological Diseases
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Author : Rui Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-14
Novel Therapeutic Target And Drug Discovery For Neurological Diseases written by Rui Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-14 with Science categories.
Cerebrovascular And Neurodegenerative Diseases New Insights Into Molecular Cell Biology And Therapeutic Targets
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Author : Sikha Saha
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-30
Cerebrovascular And Neurodegenerative Diseases New Insights Into Molecular Cell Biology And Therapeutic Targets written by Sikha Saha and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-30 with categories.
Bipolar Disorder
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Author : Stephen M. Strakowski
language : en
Publisher: Oxford University Press
Release Date : 2020-01-22
Bipolar Disorder written by Stephen M. Strakowski and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-22 with Medical categories.
Bipolar disorder is among the most common conditions affecting humankind and one of the leading causes of disability worldwide. It is a complex and dynamic psychiatric condition that makes it difficult to both understand and manage. However, with good management, people affected by bipolar disorder can lead very successful lives. This book was written specifically with new psychiatrists and mental health practitioners in mind to facilitate their ability to care for this condition. Chapters review clinical presentation and epidemiology, etiology and neurobiology, and treatment of bipolar disorder.
Central Nervous System Diseases New Insights For The Healthcare Professional 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-07-22
Central Nervous System Diseases New Insights For The Healthcare Professional 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-22 with Medical categories.
Central Nervous System Diseases: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Central Nervous System Diseases: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Central Nervous System Diseases: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
New Insights Into B Cell Subsets In Health And Disease
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Author : Judith Fraussen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-04
New Insights Into B Cell Subsets In Health And Disease written by Judith Fraussen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-04 with Medical categories.
The Molecular And Genetic Basis Of Neurologic And Psychiatric Disease
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Author : Roger N. Rosenberg
language : en
Publisher: Butterworth-Heinemann
Release Date : 2003
The Molecular And Genetic Basis Of Neurologic And Psychiatric Disease written by Roger N. Rosenberg and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
Inside the third edition of this reference, the reader will find thorough and authoritative discussions of all of these developments and their implications for clinical practice. It includes a major new section on Psychiatric Diseases; descriptions of the molecular and genetic basis of the spongiform encephalopathies as well as the expression of the prion gene under physiologic and pathologic conditions; additional coverage examines the human genome project and neurologic disease; and coverage on alzheimer's disease and related dementias.
Novel Therapeutic Target And Drug Discovery For Neurological Diseases Volume Ii
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Author : Rui Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-12
Novel Therapeutic Target And Drug Discovery For Neurological Diseases Volume Ii written by Rui Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-12 with Science categories.
This Research Topic is the second volume of the Research Topic " Novel Therapeutic Target and Drug Discovery for Neurological Diseases". Please see the first volume here. Neurological diseases represent heterogeneous disorders that involve complex pathological alterations with only a few effective treatments; therefore, there is a great need for the development of novel therapeutic targets and therapies. There are more than six hundred neurological disorders, including dementia, cerebrovascular diseases, mental illness, brain tumor, and infection-caused central diseases, all arising from disruption to the central nervous system. Researchers are attempting to identify promising targets and potential drug candidates from new biological techniques and pharmacological animal studies. Thus, novel target discovery and mechanism elucidation, as well as the development of small-molecule entities, natural compounds, and polypeptides for the treatment of neurological dysfunction, may offer exciting clues for novel therapeutic strategies to halt or mitigate the course of neurological diseases.