Animal Models In Dermatology
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Animal Models In Dermatology
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Author : Howard I. Maibach
language : en
Publisher:
Release Date : 1975
Animal Models In Dermatology written by Howard I. Maibach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Medical categories.
Animal Models Of T Cell Mediated Skin Diseases
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Author : T. Zollner
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-19
Animal Models Of T Cell Mediated Skin Diseases written by T. Zollner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-19 with Science categories.
Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.
Animal Models Of Human Inflammatory Skin Diseases
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Author : Lawrence S. Chan
language : en
Publisher: CRC Press
Release Date : 2003-12-29
Animal Models Of Human Inflammatory Skin Diseases written by Lawrence S. Chan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-29 with Medical categories.
Progress in understanding skin diseases has been aided enormously by the use of tissues derived from animals, by studying normal processes in animals, and by the development of animal models. The cellular activities in animals and humans are remarkably similar and the actual pathological process of an inflammatory skin disease can only be accurately observed and analyzed in a living animal model, and not in any in vitro model system. These factors have led to the regular use of animal tissues and models to allow the disease processes to be studied at a much greater depth. Animal Models of Human Inflammatory Skin Diseases features the principles and practices of how to go about studying inflammatory skin diseases using live animal models. On the principle side, the book describes the comparative structure and function of the skin, and the comparative immunology system in animal species commonly used as models. From the practical perspective, it presents a general discussion on methods of experimental animal modeling and contains specific expert experience on individual models. The authors include a detailed method of disease induction for each model, present chapters on comparative histology and immunology, and discuss potential targets of disease intervention. Written by biomedical investigators with first-hand experience in their chosen fields, this book is a valuable guide and reference for investigators in the biomedical and pharmaceutical sciences. It provides an instantaneous comparison between the skin structure and immunology of humans and animals, aiding in the interpretation and application of pathologic and immunologic findings.
Handbook Of Mouse Mutations With Skin And Hair Abnormalities
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Author : John P. Sundberg
language : en
Publisher: CRC Press
Release Date : 2020-08-26
Handbook Of Mouse Mutations With Skin And Hair Abnormalities written by John P. Sundberg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-26 with Medical categories.
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
Models In Dermatology Dermatopharmacology And Toxicology
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Author : Howard I. Maibach
language : en
Publisher:
Release Date : 1985
Models In Dermatology Dermatopharmacology And Toxicology written by Howard I. Maibach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with categories.
Models In Dermatology 3 1987
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Author : [Anonymus AC01222304]
language : en
Publisher:
Release Date : 1987
Models In Dermatology 3 1987 written by [Anonymus AC01222304] and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.
Dermatologic Research Techniques
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Author : Howard I. Maibach
language : en
Publisher: CRC-Press
Release Date : 1995-10-23
Dermatologic Research Techniques written by Howard I. Maibach and has been published by CRC-Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-10-23 with Medical categories.
Dermatologic Research Techniques describes and defines models in dermatology relating to animal, human, computer, and in vitro systems. It provides a valuable overview as well as in-depth evaluation of the rapidly evolving world of dermatologic research models.
Skin Tissue Models
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Author : Alexandra P. Marques
language : en
Publisher: Academic Press
Release Date : 2017-11-14
Skin Tissue Models written by Alexandra P. Marques and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-14 with Science categories.
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models. Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible
Animal Models In Biomedical Research
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Author : Cynthia Petrie Smith
language : en
Publisher:
Release Date : 1991
Animal Models In Biomedical Research written by Cynthia Petrie Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Animal models in research categories.
Small Animal Dermatology E Book
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Author : Keith A. Hnilica
language : en
Publisher: Elsevier Health Sciences
Release Date : 2010-12-02
Small Animal Dermatology E Book written by Keith A. Hnilica and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-02 with Medical categories.
Designed with busy practitioners and students in mind, Small Animal Dermatology: A Color Atlas and Therapeutic Guide provides concise, thorough coverage of over 250 skin diseases affecting small animals. More than 1,000 high-quality images help to ensure accurate diagnoses, with coverage including clinical features, top differentials, treatment, and prognosis for each disorder. In this edition, author Keith A. Hnilica streamlines content for practical, everyday use in the clinic. The differential diagnosis chapter is updated for added clarity and easier use, and for quick access, chapters now list diseases based upon the frequency of their occurrence in the pet population. A user-friendly organization allows for quick and easy access to information on specific diseases. Vivid, full-color images facilitate accurate diagnosis of each disorder. A comprehensive drug appendix includes information about dosage, adverse reactions, indications, and contraindications. A new section on skin diseases of birds and exotic pets covers the management of rabbits, ferrets, hamsters, guinea pigs, gerbils, chinchillas, turtles, snakes, and lizards. Hundreds of new, full-color images clearly demonstrate the clinical appearance of skin lesions for accurate diagnosis and treatment. Expanded coverage includes multiple methods of developing a differential diagnosis list based on patterns, breed, lesion type, and lesion location. Coverage of the zoonotic potential of animal skin diseases includes information on preventing the spread of disease from animal to human. Content is streamlined to focus on the more common and likely to be seen clinical problems. A completely updated drug formulary outlines the most effective treatment of dermatological conditions.