Animal Models Of Epilepsy
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Animal Models Of Epilepsy
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Author : Scott C. Baraban
language : en
Publisher: Humana Press
Release Date : 2016-08-23
Animal Models Of Epilepsy written by Scott C. Baraban and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.
In this book, investigators examine several novel models of epilepsy in mice as well as in genetically tractable "simple" species. This is an ideal guide for scientists who wish to expand our understanding of the pathogenesis of this neurological disorder.
Models Of Seizures And Epilepsy
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Author : Asla Pitkänen
language : en
Publisher: Academic Press
Release Date : 2017-06-14
Models Of Seizures And Epilepsy written by Asla Pitkänen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-14 with Science categories.
Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
Experimental Models Of Epilepsy And Related Comorbidities
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Author : Mohd. Farooq Shaikh
language : en
Publisher: Frontiers Media SA
Release Date : 2019-06-19
Experimental Models Of Epilepsy And Related Comorbidities written by Mohd. Farooq Shaikh and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-19 with categories.
Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational questions about epilepsy comorbidities, are used to study the relationship between epilepsy and related comorbidities. The aim of this Research Topic was to highlight basic, clinical and interdisciplinary research involved in studying the disease and its comorbid effects. Various experimental models are used to understand the mechansims of disease and to discover newer antiepileptic drugs. These experimental models combines the input from behavioral, biochemical and molecular level including genetic.
Epileptic Seizure Disorders In Animal Models Advances In Translational Approaches
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Author : Evgenia Sitnikova
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-29
Epileptic Seizure Disorders In Animal Models Advances In Translational Approaches written by Evgenia Sitnikova and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-29 with Medical categories.
Epilepsy
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Author : David W. McCandless
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-02
Epilepsy written by David W. McCandless and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-02 with Medical categories.
The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7‐9 years, and the “success” rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted in advance by animal studies. Both the time between animal and human attempts plus the success rate need improvement.
Animal Models Of Neurological Disorders
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Author : Puneet Kumar Bansal
language : en
Publisher: Springer
Release Date : 2018-01-17
Animal Models Of Neurological Disorders written by Puneet Kumar Bansal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-17 with Medical categories.
This book introduces undergraduate, postgraduate and research students and scientists to animal models of neurological disorders, along with their working principle and brief procedures. Addressing all the disorders related to the central nervous system (CNS) in a single platform, on the basis of various literature surveys it describes different procedures to induce a single disease with the help of toxins/chemicals. It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that makes specific procedures for neurological disorders available, so that specific disease can be induced in laboratories according to the availability of resources. Further, it acquaints readers with the pathological changes that occur in a particular neurological disorder, which reflect specific signs and symptoms of any particular disease, and examines how they affect everyday life. It is a valuable resource for researchers aiming to eradicate or improve neurological disorders by testing the benefits of different drugs.
Epilepsy
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Author : Jong Rho
language : en
Publisher: CRC Press
Release Date : 2010-06-18
Epilepsy written by Jong Rho and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-18 with Medical categories.
Epilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervo
Jasper S Basic Mechanisms Of The Epilepsies
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Author : Jeffrey L. Noebels
language : en
Publisher: OUP USA
Release Date : 2012-06-29
Jasper S Basic Mechanisms Of The Epilepsies written by Jeffrey L. Noebels and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-29 with Medical categories.
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Animal Models For The Study Of Human Disease
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Author : Ryuta Koyama
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-29
Animal Models For The Study Of Human Disease written by Ryuta Koyama and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-29 with Medical categories.
Epilepsy is a nervous system disorder characterized by recurrent seizures that commonly affects infants and children. It has been suggested that prolonged seizures in early life could affect the developing brain. Thus, adequate animal models for studying the causality and outcome of early-life seizures are necessary to facilitate the development of drugs and therapeutic strategies. Among early-life seizures, febrile seizures are the most common type of convulsive events in humans between 3 months and 5 years of age. Although febrile seizures are benign in most cases, it remains controversial whether complex febrile seizures are associated with the development of epilepsy later in life. To address this concern, animal models of febrile seizures have been developed and utilized to characterize the mechanisms and consequences underlying febrile seizure-induced alterations in the structure and function of neural circuits. In this chapter, the accumulated findings from experimental models of febrile seizures will be introduced and discussed.
Introduction To Epilepsy
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Author : Gonzalo Alarcón
language : en
Publisher: Cambridge University Press
Release Date : 2012-04-26
Introduction To Epilepsy written by Gonzalo Alarcón and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-26 with Medical categories.
Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.