Models Of Seizures And Epilepsy
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Models Of Seizures And Epilepsy
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Author : Asla Pitkänen
language : en
Publisher: Academic Press
Release Date : 2017-06-14
Models Of Seizures And Epilepsy written by Asla Pitkänen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-14 with Medical categories.
Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
Models Of Seizures And Epilepsy
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Author : Asla Pitkänen
language : en
Publisher: Elsevier
Release Date : 2005-10-04
Models Of Seizures And Epilepsy written by Asla Pitkänen and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-04 with Psychology categories.
An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform phenomenology (including burst discharges and seizures), and suggestions for model characterization and validation, such as electrographic, morphologic, pharmacologic, and behavioral features. Experts in the field provide not only technical reviews of these models but also conceptual critiques - commenting on the strengths and limitations of these models, their relationship to clinical phenomenology, and their value in developing a better understanding and treatments. Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field. It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research. - The first comprehensive description of animal models of epilepsy since the early 1970's - Comprehensive analysis of "What the models model" to guide the selection of each model, and what specific questions it will answer - Elegant examples of the use of novel technologies that can be applied in experimental epilepsy research - World expert opinions on the clinical relevance of each model
Epileptic Seizures And The Eeg
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Author : Andrea Varsavsky
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Epileptic Seizures And The Eeg written by Andrea Varsavsky and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
A study of epilepsy from an engineering perspective, this volume begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis and modeling of the epileptic brain. It introduces the EEG and provides an explanation of the type of brain activity likely to register in EEG measurements, offering an overview of how these EEG records are and have been analyzed in the past. The book focuses on the problem of seizure detection and surveys the physiologically based dynamic models of brain activity. Finally, it addresses the fundamental question: can seizures be predicted? Based on the authors' extensive research, the book concludes by exploring a range of future possibilities in seizure prediction.
Introduction To Epilepsy
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Author : Gonzalo Alarcón
language : en
Publisher: Cambridge University Press
Release Date : 2012-04-26
Introduction To Epilepsy written by Gonzalo Alarcón and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-26 with Medical categories.
Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.
Animal Models Of Epilepsy
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Author : Scott C. Baraban
language : en
Publisher: Humana
Release Date : 2009-05-29
Animal Models Of Epilepsy written by Scott C. Baraban and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-29 with Medical categories.
In this book, investigators examine several novel models of epilepsy in mice as well as in genetically tractable "simple" species. This is an ideal guide for scientists who wish to expand our understanding of the pathogenesis of this neurological disorder.
Seizures And Epilepsy
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Author : Jerome Engel
language : en
Publisher: Oxford University Press
Release Date : 2013-01-31
Seizures And Epilepsy written by Jerome Engel and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-31 with Medical categories.
This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.
Epilepsy
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Author : David W. McCandless
language : en
Publisher: Springer
Release Date : 2014-11-25
Epilepsy written by David W. McCandless and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-25 with Medical categories.
The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7‐9 years, and the “success” rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted in advance by animal studies. Both the time between animal and human attempts plus the success rate need improvement.
Jasper S Basic Mechanisms Of The Epilepsies
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Author : Jeffrey Noebels
language : en
Publisher: OUP USA
Release Date : 2012-06-29
Jasper S Basic Mechanisms Of The Epilepsies written by Jeffrey Noebels and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-29 with Medical categories.
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Epilepsy
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Author : Jong Rho
language : en
Publisher: CRC Press
Release Date : 2010-06-18
Epilepsy written by Jong Rho and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-18 with Medical categories.
Epilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervo
Computational Neuroscience In Epilepsy
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Author : Ivan Soltesz
language : en
Publisher: Academic Press
Release Date : 2011-09-02
Computational Neuroscience In Epilepsy written by Ivan Soltesz and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-02 with Science categories.
Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering. - Covers a wide range of topics from molecular to seizure predictions and brain implants to control seizures - Contributors are top experts at the forefront of computational epilepsy research - Chapter contents are highly relevant to both basic and clinical epilepsy researchers