Computational Neuroscience In Epilepsy
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Computational Neuroscience In Epilepsy
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Author : Ivan Soltesz
language : en
Publisher: Academic Press
Release Date : 2011-09-02
Computational Neuroscience In Epilepsy written by Ivan Soltesz and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-02 with Science categories.
Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering. - Covers a wide range of topics from molecular to seizure predictions and brain implants to control seizures - Contributors are top experts at the forefront of computational epilepsy research - Chapter contents are highly relevant to both basic and clinical epilepsy researchers
Computational Neurology And Psychiatry
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Author : Péter Érdi
language : en
Publisher: Springer
Release Date : 2017-01-25
Computational Neurology And Psychiatry written by Péter Érdi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-25 with Technology & Engineering categories.
This book presents the latest research in computational methods for modeling and simulating brain disorders. In particular, it shows how mathematical models can be used to study the relationship between a given disorder and the specific brain structure associated with that disorder. It also describes the emerging field of computational psychiatry, including the study of pathological behavior due to impaired functional connectivity, pathophysiological activity, and/or aberrant decision-making. Further, it discusses the data analysis techniques that will be required to analyze the increasing amount of data being generated about the brain. Lastly, the book offers some tips on the application of computational models in the field of quantitative systems pharmacology. Mainly written for computational scientists eager to discover new application fields for their model, this book also benefits neurologists and psychiatrists wanting to learn about new methods.
Validating Neuro Computational Models Of Neurological And Psychiatric Disorders
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Author : Basabdatta Sen Bhattacharya
language : en
Publisher: Springer
Release Date : 2015-10-30
Validating Neuro Computational Models Of Neurological And Psychiatric Disorders written by Basabdatta Sen Bhattacharya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-30 with Medical categories.
This book is a collection of articles by leading researchers working at the cutting edge of neuro-computational modelling of neurological and psychiatric disorders. Each article contains model validation techniques used in the context of the specific problem being studied. Validation is essential for neuro-inspired computational models to become useful tools in the understanding and treatment of disease conditions. Currently, the immense diversity in neuro-computational modelling approaches for investigating brain diseases has created the need for a structured and coordinated approach to benchmark and standardise validation methods and techniques in this field of research. This book serves as a step towards a systematic approach to validation of neuro-computational models used for studying brain diseases and should be useful for all neuro-computational modellers.
Jasper S Basic Mechanisms Of The Epilepsies
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Author : Jeffrey Noebels
language : en
Publisher: Oxford University Press
Release Date : 2012-06-01
Jasper S Basic Mechanisms Of The Epilepsies written by Jeffrey Noebels and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-01 with Medical categories.
H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous expansion in the understanding of basic epilepsy mechanisms over the past four decades, this fourth edition of Jasper's BME is the most ambitious yet. In 90 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility, and ultimately epileptogenesis. It provides a framework for expanding the epilepsy genome and understanding the complex heredity responsible for common epilepsies as it explores disease mechanisms of ion channelopathies and developmental epilepsy genes. It considers the mechanisms of conditions of epilepsy comorbidities. And, for the first time, this 4th edition describes the current efforts to translate the discoveries in epilepsy disease mechanisms into new therapeutic strategies. This book, considered the 'bible' of basic epilepsy research, is essential for the student, the clinician scientist and all research scientists who conduct laboratory-based experimental epilepsy research using cellular, brain slice and animal models, as well as for those interested in related disciplines of neuronal oscillations, network plasticity, and signaling in brain strucutres that include the cortex, hippocampus, and thalamus. In keeping with the 1969 goals, the book is now of practical importance to the clinical neurologist and epileptologist as the progress of research in molecular genetics and modern efforts to design antiepileptic drugs, cures and repairs in the epilepsies converge and impact clinical care.
The Changing Face Of Epilepsy Surgery Contributions Of Computational Neuroscience And Robotics To The Field
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Author : Jorge Alvaro Gonzalez-Martinez
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-09
The Changing Face Of Epilepsy Surgery Contributions Of Computational Neuroscience And Robotics To The Field written by Jorge Alvaro Gonzalez-Martinez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-09 with Medical categories.
Topic Editor Prof. Jorge Alvaro Gonzalez-Martinez has received a consulting grant from Zimmer Biomet. Prof. Stéphan Chabardès has also worked as a consultant for Zimmer Biomet. Prof. Chauvel has declared no competing interests with regards to the Research Topic subject.
Neurobiology Of Epilepsy
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-06-20
Neurobiology Of Epilepsy written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-20 with Medical categories.
Neurobiology of Epilepsy: From Genes to Networks is the latest volume in the Progress in Brain Research series that focuses on new trends and developments. This established international series examines major areas of basic and clinical research within the neurosciences, as well as popular and emerging subfields. - Explores new trends and developments in the neurobiology of Epilepsy - Enhances the literature of neuroscience by further expanding the established, ongoing international series - Progress in Brain Research - Examines major areas of basic and clinical research within the field
Neurobiology Of The Epilepsies
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Author : Jerome Engel, Jr.
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2022-08-30
Neurobiology Of The Epilepsies written by Jerome Engel, Jr. and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-30 with Medical categories.
Neurobiology of the Epilepsies – From Epilepsy: A Comprehensive Textbook, 3rd Edition, provides a concise, up-to-date review of basic sciences and the latest research advances in epilepsy. Ideal for general neurologists and neurosurgeons, epilepsy/clinical neurophysiology specialists, basic scientists, clinical researchers, and other health care providers with an interest in epilepsy, this new volume by Drs. Istvan Mody, Hal Blumenfeld, Jerome Engel, Jr., Asla Ptkänen, Ivan Soltesz, and Annamaria Vezzani offers comprehensive, authoritative coverage of this critical and complex area of the field.
Models Of Seizures And Epilepsy
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Author : Asla Pitkänen
language : en
Publisher: Academic Press
Release Date : 2017-06-14
Models Of Seizures And Epilepsy written by Asla Pitkänen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-14 with Medical categories.
Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
Seizure Prediction In Epilepsy
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Author : Björn Schelter
language : en
Publisher: John Wiley & Sons
Release Date : 2008-11-21
Seizure Prediction In Epilepsy written by Björn Schelter and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-21 with Science categories.
Comprising some 30 contributions, experts from around the world present and discuss recent advances related to seizure prediction in epilepsy. The book covers an extraordinarily broad spectrum, starting from modeling epilepsy in single cells or networks of a few cells to precisely-tailored seizure prediction techniques as applied to human data. This unique overview of our current level of knowledge and future perspectives provides theoreticians as well as practitioners, newcomers and experts with an up-to-date survey of developments in this important field of research.
Epilepsy
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Author : Ivan Osorio
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Epilepsy written by Ivan Osorio and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Epilepsy, one of the most prevalent neurological disorders, affects approximately 1% (greater than 60 million) of the world's population. In an estimated 20 million of these patients, seizures are not controlled even by multiple anti-seizure drugs, and are extremely difficult to predict. Epilepsy: The Intersection of Neurosciences, Biology, Mathema