Antigen Presentation
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Antigen Presentation
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Author : J. Lindsay Whitton
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07
Antigen Presentation written by J. Lindsay Whitton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.
Antigen presentation is central to the immune response, and is instrumental in ensuring that the response mounted is that best suited to the eradication of the particular microbe faced. In this volume, experts in the field provide state-of-the-art descriptions of the antigen presentation pathways. How do viruses disrupt these critical pathways, and to what effect? Do all tissues present antigen in the same way? If not, why? What are the consequences of dysfunctional antigen presentation, seen in certain genetic disorders? This book considers not only the molecular details, but also their relevance to the whole organism.
Processing And Presentation Of Antigens
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Author : Benvenuto Pernis
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Processing And Presentation Of Antigens written by Benvenuto Pernis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Health & Fitness categories.
Processing and Presentation of Antigens brings together the views of immunologists, biochemists, cell biologists, and virologists who have a common interest in the early phases of the immune response. Antigen processing and presentation comprise a series of events that are much more complex and sophisticated than had been thought for a long time, and constitute an essential part of the biology of the immune response to T-dependent protein antigens. The book is organized into seven parts. Part I discusses the major advances and insights in antigen processing, some results on the interaction of antigen with class II MHC molecules, and the precise mechanism involved in antigen processing. Part II presents papers on endosomes, lysosomes, and recycling. Part III deals with studies on presentation in the context of class I MHC molecules. The chapters in Part IV examine interactions of antigens with class II MHC molecules. Part V contains papers on macrophages and dendritic cells as accessory cells. Part VI examines antigen presentation by B cells. Part VII covers studies on T cells.
Antigen Presenting Cells
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Author : Harald Kropshofer
language : en
Publisher: John Wiley & Sons
Release Date : 2006-05-12
Antigen Presenting Cells written by Harald Kropshofer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-12 with Science categories.
This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system. Structured in a clear way to allow access to a very broad readership, the book is written from the viewpoint of a biochemist, immunologist, and scientist with experience in drug development. It covers all cell types involved in antigen presentation, providing the latest immunological facts with a focus on drug development. Backed by a glossary explaining all important technical terms, this short but comprehensive reference covers basic introductory aspects right up to details for advanced specialists.
Antigen Processing And Presentation Protocols
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Author : Joyce C. Solheim
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-26
Antigen Processing And Presentation Protocols written by Joyce C. Solheim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-26 with Medical categories.
Antigen processing and presentation, as a field, explores a broad range of protein interactions and functions, both intracellular (in the cytoplasm and in the endoplasmic reticulum) and at the cell surface (between T cells and MHC molecules). To investigate such a diverse array, it is necessary that biochemical, cell biology, and immunological techniques all be employed. The purpose of Antigen Processing and Presentation Protocols is therefore to detail the most up-to-date techniques being used in this burgeoning field. Such techniques include those used to question how MHC-binding peptides are generated, to test how peptides are delivered to MHC molecules, to analyze MHC peptide-binding patterns, and to assay the T-cell response to MHC/peptide. Antigen Processing and Presentation Protocols should aid both those new and those experienced in this area of research in extending the questions that can be asked and answered by the application of these current methods. For editorial assistance, I would like to thank Angela Beninga and Rachael Turnquist.
Application Of Antigen Cross Presentation Research Into Patient Care
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Author : Marianne Boes
language : en
Publisher: Frontiers Media SA
Release Date : 2017-05-16
Application Of Antigen Cross Presentation Research Into Patient Care written by Marianne Boes and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-16 with Electronic book categories.
The activation of adaptive immune responses requires the processing and presentation of protein antigens to lymphocytes. Especially dendritic cells are effective at display of antigen-derived peptides in the form of immunogenic peptide/MHC complexes to CD4 and CD8-positive T cells, and can stimulate even naive T cells to clonally expand. During the last 40 years, mechanisms that facilitate antigen processing and presentation were clarified, mostly from work in cell lines and mouse models. From mouse-based work, it is now clear that dendritic cells represent a collection of specialized cell subsets that are particularly well endowed to stimulate antigen transport to distinct tissue locations, to transfer antigens between cellular subsets or to trigger T cell responses. Dendritic cell subsets hold great promise for therapeutic application, for example as dendritic cell-based vaccines to bolster immune responses against viruses or malignant growths. Hurdles remain that preclude the efficient application of high quality pre-clinical research into standardized patient care. In this research topic, efforts in dendritic cell research and dendritic cell-based vaccines are discussed, from both pre-clinical and application points of view.
Antigen Processing And Presentation
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Author : Robert Edward Humphreys
language : en
Publisher:
Release Date : 1994
Antigen Processing And Presentation written by Robert Edward Humphreys and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
One of the few volumes dedicated to antigen processing, this unique text is not only especially current but also valuable for its description of petentially "hot" areas with its "Future Directions" sections. * Current, important topics covered by this text include: Processing and presentation of foreign and self protein antigens to T lymphocytes Intracellular assembley and transport of MHC proteins Regulation of the assembley and expression of processed antigen-MHC complexes
Immunobiology Of Proteins And Peptides Iv
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Author : M. Zouhair Atassi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunobiology Of Proteins And Peptides Iv written by M. Zouhair Atassi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This symposium was established in 1976 for the purpose of bringing to gether once every two or three years, active investigators in the fore front of contemporary immunology, to present their findings and to discuss their significance in the light of current concepts and to identify important new directions of investigation. The founding of the symposium was stimulated by the achievement of major breakthroughs in the under standing of the immune recognition of proteins and peptides. We believed that these breakthroughs will lead to the creation of a new generation of peptides which should have enormous potential in biological, therapeutic and basic applications. This anticipated explosion has finally occurred and many applications of these peptides are now being realized. The main symposia topics of the fourth symposium were: T-cell recognition of proteins, structure and function of the T-cell receptor, presentation of protein antigens, recycling and activation of membrane receptor molecules, Ir-gene control of T-cell responses and methods of cell separation. The molecular features recognized by antibodies on proteins were the first immune recognition sites to be local ized and confirmed by synthetic peptides. The complete antigenic structures of several proteins have been defined, and individual antigenic sites have been described on many more proteins. More recently, major breakthroughs have been reported in the immune recognition of proteins by T cells.
Antigen Presenting Cells
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Author : Jonathan M. Austyn
language : en
Publisher: Oxford University Press, USA
Release Date : 1989
Antigen Presenting Cells written by Jonathan M. Austyn and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Language Arts & Disciplines categories.
This concise text provides detailed guidance on antigen-presenting cells, a relatively new area which has until now been inadequately treated textually. The reader will find information on all aspects of antigen presentation, including coverage of thymic development of T cells, immunostimulation of resting T cells in secondary lymphoid tissue, and the effector stages of immune response. The latest research on the molecular pathways of antigen processing, and the ways in which MHC molecules bind to antigenic receptor cells to stimulate helper T cells is given careful, focused attention, while the role of antigen presentation in immune response is covered in-depth. This ideal guide for undergraduate and graduate students in biology and medicine is presented in any easy-to-read format, and includes many helpful diagrams and two-color illustrations.
Antigen Presentation By Intestinal Epithelial Cells
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Author : Dominique Kaiserlian
language : en
Publisher: Landes Bioscience
Release Date : 1996
Antigen Presentation By Intestinal Epithelial Cells written by Dominique Kaiserlian and has been published by Landes Bioscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
Antigen Presenting Cells Advances In Research And Application 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-06-21
Antigen Presenting Cells Advances In Research And Application 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-21 with Medical categories.
Antigen-Presenting Cells—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Antigen-Presenting Cells—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antigen-Presenting Cells—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.