Applied Microbiome Statistics
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Applied Microbiome Statistics
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Author : Yinglin Xia
language : en
Publisher: CRC Press
Release Date : 2024-07-22
Applied Microbiome Statistics written by Yinglin Xia and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-22 with Mathematics categories.
This unique book officially defines microbiome statistics as a specific new field of statistics and addresses the statistical analysis of correlation, association, interaction, and composition in microbiome research. It also defines the study of the microbiome as a hypothesis-driven experimental science and describes two microbiome research themes and six unique characteristics of microbiome data, as well as investigating challenges for statistical analysis of microbiome data using the standard statistical methods. This book is useful for researchers of biostatistics, ecology, and data analysts. Presents a thorough overview of statistical methods in microbiome statistics of parametric and nonparametric correlation, association, interaction, and composition adopted from classical statistics and ecology and specifically designed for microbiome research. Performs step-by-step statistical analysis of correlation, association, interaction, and composition in microbiome data. Discusses the issues of statistical analysis of microbiome data: high dimensionality, compositionality, sparsity, overdispersion, zero-inflation, and heterogeneity. Investigates statistical methods on multiple comparisons and multiple hypothesis testing and applications to microbiome data. Introduces a series of exploratory tools to visualize composition and correlation of microbial taxa by barplot, heatmap, and correlation plot. Employs the Kruskal–Wallis rank-sum test to perform model selection for further multi-omics data integration. Offers R code and the datasets from the authors’ real microbiome research and publicly available data for the analysis used. Remarks on the advantages and disadvantages of each of the methods used.
Topics In Applied Statistics
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Author : Mingxiu Hu
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-09-14
Topics In Applied Statistics written by Mingxiu Hu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-14 with Medical categories.
This volume presents 27 selected papers in topics that range from statistical applications in business and finance to applications in clinical trials and biomarker analysis. All papers feature original, peer-reviewed content. The editors intentionally selected papers that cover many topics so that the volume will serve the whole statistical community and a variety of research interests. The papers represent select contributions to the 21st ICSA Applied Statistics Symposium. The International Chinese Statistical Association (ICSA) Symposium took place between the 23rd and 26th of June, 2012 in Boston, Massachusetts. It was co-sponsored by the International Society for Biopharmaceutical Statistics (ISBS) and American Statistical Association (ASA). This is the inaugural proceedings volume to share research from the ICSA Applied Statistics Symposium.
Statistical And Computational Methods For Microbiome Multi Omics Data
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Author : Himel Mallick
language : en
Publisher: Frontiers Media SA
Release Date : 2020-11-19
Statistical And Computational Methods For Microbiome Multi Omics Data written by Himel Mallick and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-19 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Statistical Analysis Of Microbiome Data With R
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Author : Yinglin Xia
language : en
Publisher: Springer
Release Date : 2018-10-06
Statistical Analysis Of Microbiome Data With R written by Yinglin Xia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-06 with Computers categories.
This unique book addresses the statistical modelling and analysis of microbiome data using cutting-edge R software. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of R for data analysis step by step. The data and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter, so that these new methods can be readily applied in their own research. The book also discusses recent developments in statistical modelling and data analysis in microbiome research, as well as the latest advances in next-generation sequencing and big data in methodological development and applications. This timely book will greatly benefit all readers involved in microbiome, ecology and microarray data analyses, as well as other fields of research.
Methodological And Applied Statistics And Demography Iv
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Author : Alessio Pollice
language : en
Publisher: Springer Nature
Release Date : 2025-01-20
Methodological And Applied Statistics And Demography Iv written by Alessio Pollice and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-20 with Mathematics categories.
This book of peer-reviewed short papers on methodological and applied statistics and demography is the fourth of four volumes from the 52nd Scientific Meeting of the Italian Statistical Society (SIS 2024), held in Bari, Italy, on June 17-20, 2024. It features the second part of the contributions presented in the Contributed Sessions. The volumes address a large number of topics and applications of current interest. The topics covered include, but are not limited to, statistical theory and methods, sampling theory, Bayesian statistics, statistical modeling, computational statistics, classification, data analysis, gender statistics and applied statistics. The applications reflect new analyses in a wide variety of fields, including demography, psychometrics, education, business, economics, finance, law, and other social sciences and humanities, epidemiology, the life and health sciences as well as the environmental and natural sciences and engineering. This variety also demonstrates the important role of statistical science in addressing the societal and environmental challenges of sustainable development. One of the aims of the Italian Statistical Society (SIS) is to promote scientific activities for the development of statistical sciences. Its biennial international Scientific Meeting represents the Society’s largest event which brings together national and international researchers and professionals to exchange ideas and discuss recent advances and developments in theoretical and applied statistics.
Methodological And Applied Statistics And Demography Ii
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Author : Alessio Pollice
language : en
Publisher: Springer Nature
Release Date : 2025-03-02
Methodological And Applied Statistics And Demography Ii written by Alessio Pollice and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-02 with Mathematics categories.
This book of peer-reviewed short papers on methodological and applied statistics and demography is the second of four volumes from the 52nd Scientific Meeting of the Italian Statistical Society (SIS 2024), held in Bari, Italy, on June 17-20, 2024. It features invited contributions presented in the Solicited Sessions. The volumes address a large number of topics and applications of current interest. The topics covered include, but are not limited to, statistical theory and methods, sampling theory, Bayesian statistics, statistical modeling, computational statistics, classification, data analysis, gender statistics and applied statistics. The applications reflect new analyses in a wide variety of fields, including demography, psychometrics, education, business, economics, finance, law, and other social sciences and humanities, epidemiology, the life and health sciences as well as the environmental and natural sciences and engineering. This variety also demonstrates the important role of statistical science in addressing the societal and environmental challenges of sustainable development. One of the aims of the Italian Statistical Society (SIS) is to promote scientific activities for the development of statistical sciences. Its biennial international Scientific Meeting represents the Society’s largest event which brings together national and international researchers and professionals to exchange ideas and discuss recent advances and developments in theoretical and applied statistics.
Statistical Data Analysis Of Microbiomes And Metabolomics
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Author : Yinglin Xia
language : en
Publisher: American Chemical Society
Release Date : 2022-02-03
Statistical Data Analysis Of Microbiomes And Metabolomics written by Yinglin Xia and has been published by American Chemical Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-03 with Science categories.
Compared with other research fields, both microbiome and metabolomics data are complicated and have some unique characteristics, respectively. Thus, choosing an appropriate statistical test or method is a very important step in the analysis of microbiome and metabolomics data. However, this is still a difficult task for those biomedical researchers without a statistical background and for those biostatisticians who do not have research experiences in these fields. Graduate students studying microbiome and metabolomics; statisticians, working on microbiome and metabolomics projects, either for their own research, or for their collaborative research for experimental design, grant application, and data analysis; and researchers who investigate biomedical and biochemical projects with the microbiome, metabolome, and multi-omics data analysis will benefit from reading this work.
Novel Approaches In Microbiome Analyses And Data Visualization
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Author : Jessica Galloway-Peña
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-06
Novel Approaches In Microbiome Analyses And Data Visualization written by Jessica Galloway-Peña and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with categories.
High-throughput sequencing technologies are widely used to study microbial ecology across species and habitats in order to understand the impacts of microbial communities on host health, metabolism, and the environment. Due to the dynamic nature of microbial communities, longitudinal microbiome analyses play an essential role in these types of investigations. Key questions in microbiome studies aim at identifying specific microbial taxa, enterotypes, genes, or metabolites associated with specific outcomes, as well as potential factors that influence microbial communities. However, the characteristics of microbiome data, such as sparsity and skewedness, combined with the nature of data collection, reflected often as uneven sampling or missing data, make commonly employed statistical approaches to handle repeated measures in longitudinal studies inadequate. Therefore, many researchers have begun to investigate methods that could improve incorporating these features when studying clinical, host, metabolic, or environmental associations with longitudinal microbiome data. In addition to the inferential aspect, it is also becoming apparent that visualization of high dimensional data in a way which is both intelligible and comprehensive is another difficult challenge that microbiome researchers face. Visualization is crucial in both the analysis and understanding of metagenomic data. Researchers must create clear graphic representations that give biological insight without being overly complicated. Thus, this Research Topic seeks to both review and provide novels approaches that are being developed to integrate microbiome data and complex metadata into meaningful mathematical, statistical and computational models. We believe this topic is fundamental to understanding the importance of microbial communities and provides a useful reference for other investigators approaching the field.
Bioinformatic And Statistical Analysis Of Microbiome Data
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Author : Yinglin Xia
language : en
Publisher: Springer Nature
Release Date : 2023-06-16
Bioinformatic And Statistical Analysis Of Microbiome Data written by Yinglin Xia and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-16 with Science categories.
This unique book addresses the bioinformatic and statistical modelling and also the analysis of microbiome data using cutting-edge QIIME 2 and R software. It covers core analysis topics in both bioinformatics and statistics, which provides a complete workflow for microbiome data analysis: from raw sequencing reads to community analysis and statistical hypothesis testing. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of QIIME 2 and R for data analysis step-by-step. The data as well as QIIME 2 and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter so that these new methods can be readily applied in their own research. Bioinformatic and Statistical Analysis of Microbiome Data is an ideal book for advanced graduate students and researchers in the clinical, biomedical, agricultural, and environmental fields, as well as those studying bioinformatics, statistics, and big data analysis.
Microbiome And Machine Learning
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Author : Isabel Moreno Indias
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-02
Microbiome And Machine Learning written by Isabel Moreno Indias and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-02 with Science categories.