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Bayesian Biostatistics And Diagnostic Medicine


Bayesian Biostatistics And Diagnostic Medicine
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Bayesian Biostatistics And Diagnostic Medicine


Bayesian Biostatistics And Diagnostic Medicine
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Author : Lyle D. Broemeling
language : en
Publisher: CRC Press
Release Date : 2007-07-12

Bayesian Biostatistics And Diagnostic Medicine written by Lyle D. Broemeling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-12 with Mathematics categories.


There are numerous advantages to using Bayesian methods in diagnostic medicine, which is why they are employed more and more today in clinical studies. Exploring Bayesian statistics at an introductory level, Bayesian Biostatistics and Diagnostic Medicine illustrates how to apply these methods to solve important problems in medicine and biology.



Bayesian Thinking In Biostatistics


Bayesian Thinking In Biostatistics
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Author : Gary L Rosner
language : en
Publisher: CRC Press
Release Date : 2021-03-16

Bayesian Thinking In Biostatistics written by Gary L Rosner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-16 with Mathematics categories.


Praise for Bayesian Thinking in Biostatistics: "This thoroughly modern Bayesian book ...is a 'must have' as a textbook or a reference volume. Rosner, Laud and Johnson make the case for Bayesian approaches by melding clear exposition on methodology with serious attention to a broad array of illuminating applications. These are activated by excellent coverage of computing methods and provision of code. Their content on model assessment, robustness, data-analytic approaches and predictive assessments...are essential to valid practice. The numerous exercises and professional advice make the book ideal as a text for an intermediate-level course..." -Thomas Louis, Johns Hopkins University "The book introduces all the important topics that one would usually cover in a beginning graduate level class on Bayesian biostatistics. The careful introduction of the Bayesian viewpoint and the mechanics of implementing Bayesian inference in the early chapters makes it a complete self- contained introduction to Bayesian inference for biomedical problems....Another great feature for using this book as a textbook is the inclusion of extensive problem sets, going well beyond construed and simple problems. Many exercises consider real data and studies, providing very useful examples in addition to serving as problems." - Peter Mueller, University of Texas With a focus on incorporating sensible prior distributions and discussions on many recent developments in Bayesian methodologies, Bayesian Thinking in Biostatistics considers statistical issues in biomedical research. The book emphasizes greater collaboration between biostatisticians and biomedical researchers. The text includes an overview of Bayesian statistics, a discussion of many of the methods biostatisticians frequently use, such as rates and proportions, regression models, clinical trial design, and methods for evaluating diagnostic tests. Key Features Applies a Bayesian perspective to applications in biomedical science Highlights advances in clinical trial design Goes beyond standard statistical models in the book by introducing Bayesian nonparametric methods and illustrating their uses in data analysis Emphasizes estimation of biomedically relevant quantities and assessment of the uncertainty in this estimation Provides programs in the BUGS language, with variants for JAGS and Stan, that one can use or adapt for one's own research The intended audience includes graduate students in biostatistics, epidemiology, and biomedical researchers, in general Authors Gary L. Rosner is the Eli Kennerly Marshall, Jr., Professor of Oncology at the Johns Hopkins School of Medicine and Professor of Biostatistics at the Johns Hopkins Bloomberg School of Public Health. Purushottam (Prakash) W. Laud is Professor in the Division of Biostatistics, and Director of the Biostatistics Shared Resource for the Cancer Center, at the Medical College of Wisconsin. Wesley O. Johnson is professor Emeritus in the Department of Statistics as the University of California, Irvine.



Bayesian Biostatistics


Bayesian Biostatistics
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Author : Emmanuel Lesaffre
language : en
Publisher: John Wiley & Sons
Release Date : 2012-06-18

Bayesian Biostatistics written by Emmanuel Lesaffre and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-18 with Medical categories.


The growth of biostatistics has been phenomenal in recent years and has been marked by considerable technical innovation in both methodology and computational practicality. One area that has experienced significant growth is Bayesian methods. The growing use of Bayesian methodology has taken place partly due to an increasing number of practitioners valuing the Bayesian paradigm as matching that of scientific discovery. In addition, computational advances have allowed for more complex models to be fitted routinely to realistic data sets. Through examples, exercises and a combination of introductory and more advanced chapters, this book provides an invaluable understanding of the complex world of biomedical statistics illustrated via a diverse range of applications taken from epidemiology, exploratory clinical studies, health promotion studies, image analysis and clinical trials. Key Features: Provides an authoritative account of Bayesian methodology, from its most basic elements to its practical implementation, with an emphasis on healthcare techniques. Contains introductory explanations of Bayesian principles common to all areas of application. Presents clear and concise examples in biostatistics applications such as clinical trials, longitudinal studies, bioassay, survival, image analysis and bioinformatics. Illustrated throughout with examples using software including WinBUGS, OpenBUGS, SAS and various dedicated R programs. Highlights the differences between the Bayesian and classical approaches. Supported by an accompanying website hosting free software and case study guides. Bayesian Biostatistics introduces the reader smoothly into the Bayesian statistical methods with chapters that gradually increase in level of complexity. Master students in biostatistics, applied statisticians and all researchers with a good background in classical statistics who have interest in Bayesian methods will find this book useful.



Bayesian Survival Analysis


Bayesian Survival Analysis
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Author : Joseph G. Ibrahim
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Bayesian Survival Analysis written by Joseph G. Ibrahim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


Survival analysis arises in many fields of study including medicine, biology, engineering, public health, epidemiology, and economics. This book provides a comprehensive treatment of Bayesian survival analysis. Several topics are addressed, including parametric models, semiparametric models based on prior processes, proportional and non-proportional hazards models, frailty models, cure rate models, model selection and comparison, joint models for longitudinal and survival data, models with time varying covariates, missing covariate data, design and monitoring of clinical trials, accelerated failure time models, models for mulitivariate survival data, and special types of hierarchial survival models. Also various censoring schemes are examined including right and interval censored data. Several additional topics are discussed, including noninformative and informative prior specificiations, computing posterior qualities of interest, Bayesian hypothesis testing, variable selection, model selection with nonnested models, model checking techniques using Bayesian diagnostic methods, and Markov chain Monte Carlo (MCMC) algorithms for sampling from the posteiror and predictive distributions. The book presents a balance between theory and applications, and for each class of models discussed, detailed examples and analyses from case studies are presented whenever possible. The applications are all essentially from the health sciences, including cancer, AIDS, and the environment. The book is intended as a graduate textbook or a reference book for a one semester course at the advanced masters or Ph.D. level. This book would be most suitable for second or third year graduate students in statistics or biostatistics. It would also serve as a useful reference book for applied or theoretical researchers as well as practitioners.



Statistical Methods In Diagnostic Medicine


Statistical Methods In Diagnostic Medicine
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Author : Xiao-Hua Zhou
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-25

Statistical Methods In Diagnostic Medicine written by Xiao-Hua Zhou and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-25 with Mathematics categories.


An important role of diagnostic medicine research is to estimate and compare the accuracies of diagnostic tests. This book provides a comprehensive account of statistical methods for design and analysis of diagnostic studies, including sample size calculations, estimation of the accuracy of a diagnostic test, comparison of accuracies of competing diagnostic tests, and regression analysis of diagnostic accuracy data. Discussing recently developed methods for correction of verification bias and imperfect reference bias, methods for analysis of clustered diagnostic accuracy data, and meta-analysis methods, Statistical Methods in Diagnostic Medicine explains: * Common measures of diagnostic accuracy and designs for diagnostic accuracy studies * Methods of estimation and hypothesis testing of the accuracy of diagnostic tests * Meta-analysis * Advanced analytic techniques-including methods for comparing correlated ROC curves in multi-reader studies, correcting verification bias, and correcting when an imperfect gold standard is used Thoroughly detailed with numerous applications and end-of-chapter problems as well as a related FTP site providing FORTRAN program listings, data sets, and instructional hints, Statistical Methods in Diagnostic Medicine is a valuable addition to the literature of the field, serving as a much-needed guide for both clinicians and advanced students.



Advanced Bayesian Methods For Medical Test Accuracy


Advanced Bayesian Methods For Medical Test Accuracy
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Author : Lyle D. Broemeling
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Advanced Bayesian Methods For Medical Test Accuracy written by Lyle D. Broemeling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Mathematics categories.


Useful in many areas of medicine and biology, Bayesian methods are particularly attractive tools for the design of clinical trials and diagnostic tests, which are based on established information, usually from related previous studies. Advanced Bayesian Methods for Medical Test Accuracy begins with a review of the usual measures such as specificity



Bayesian Methods For Data Analysis Third Edition


Bayesian Methods For Data Analysis Third Edition
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Author : Bradley P. Carlin
language : en
Publisher: CRC Press
Release Date : 2008-06-30

Bayesian Methods For Data Analysis Third Edition written by Bradley P. Carlin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-30 with Mathematics categories.


Broadening its scope to nonstatisticians, Bayesian Methods for Data Analysis, Third Edition provides an accessible introduction to the foundations and applications of Bayesian analysis. Along with a complete reorganization of the material, this edition concentrates more on hierarchical Bayesian modeling as implemented via Markov chain Monte Carlo (MCMC) methods and related data analytic techniques. New to the Third Edition New data examples, corresponding R and WinBUGS code, and homework problems Explicit descriptions and illustrations of hierarchical modeling—now commonplace in Bayesian data analysis A new chapter on Bayesian design that emphasizes Bayesian clinical trials A completely revised and expanded section on ranking and histogram estimation A new case study on infectious disease modeling and the 1918 flu epidemic A solutions manual for qualifying instructors that contains solutions, computer code, and associated output for every homework problem—available both electronically and in print Ideal for Anyone Performing Statistical Analyses Focusing on applications from biostatistics, epidemiology, and medicine, this text builds on the popularity of its predecessors by making it suitable for even more practitioners and students.



Statistical Evaluation Of Diagnostic Performance


Statistical Evaluation Of Diagnostic Performance
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Author : Kelly H. Zou
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Statistical Evaluation Of Diagnostic Performance written by Kelly H. Zou and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Mathematics categories.


Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statistical classifiers, as well as for evaluating predictive models or algorithms. This book presents innovative approaches in ROC analysis, which are releva



Bayesian Ideas And Data Analysis


Bayesian Ideas And Data Analysis
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Author : Ronald Christensen
language : en
Publisher: CRC Press
Release Date : 2011-07-07

Bayesian Ideas And Data Analysis written by Ronald Christensen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-07 with Mathematics categories.


Emphasizing the use of WinBUGS and R to analyze real data, Bayesian Ideas and Data Analysis: An Introduction for Scientists and Statisticians presents statistical tools to address scientific questions. It highlights foundational issues in statistics, the importance of making accurate predictions, and the need for scientists and statisticians to collaborate in analyzing data. The WinBUGS code provided offers a convenient platform to model and analyze a wide range of data. The first five chapters of the book contain core material that spans basic Bayesian ideas, calculations, and inference, including modeling one and two sample data from traditional sampling models. The text then covers Monte Carlo methods, such as Markov chain Monte Carlo (MCMC) simulation. After discussing linear structures in regression, it presents binomial regression, normal regression, analysis of variance, and Poisson regression, before extending these methods to handle correlated data. The authors also examine survival analysis and binary diagnostic testing. A complementary chapter on diagnostic testing for continuous outcomes is available on the book’s website. The last chapter on nonparametric inference explores density estimation and flexible regression modeling of mean functions. The appropriate statistical analysis of data involves a collaborative effort between scientists and statisticians. Exemplifying this approach, Bayesian Ideas and Data Analysis focuses on the necessary tools and concepts for modeling and analyzing scientific data. Data sets and codes are provided on a supplemental website.



Bayesian Methods For Measures Of Agreement


Bayesian Methods For Measures Of Agreement
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Author : Lyle D. Broemeling
language : en
Publisher: CRC Press
Release Date : 2009-01-12

Bayesian Methods For Measures Of Agreement written by Lyle D. Broemeling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-12 with Mathematics categories.


Using WinBUGS to implement Bayesian inferences of estimation and testing hypotheses, Bayesian Methods for Measures of Agreement presents useful methods for the design and analysis of agreement studies. It focuses on agreement among the various players in the diagnostic process.The author employs a Bayesian approach to provide statistical inferences