Statistical Methods In Diagnostic Medicine
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Statistical Methods In Diagnostic Medicine
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Author : Xiao-Hua Zhou
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-25
Statistical Methods In Diagnostic Medicine written by Xiao-Hua Zhou and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-25 with Mathematics categories.
An important role of diagnostic medicine research is to estimate and compare the accuracies of diagnostic tests. This book provides a comprehensive account of statistical methods for design and analysis of diagnostic studies, including sample size calculations, estimation of the accuracy of a diagnostic test, comparison of accuracies of competing diagnostic tests, and regression analysis of diagnostic accuracy data. Discussing recently developed methods for correction of verification bias and imperfect reference bias, methods for analysis of clustered diagnostic accuracy data, and meta-analysis methods, Statistical Methods in Diagnostic Medicine explains: * Common measures of diagnostic accuracy and designs for diagnostic accuracy studies * Methods of estimation and hypothesis testing of the accuracy of diagnostic tests * Meta-analysis * Advanced analytic techniques-including methods for comparing correlated ROC curves in multi-reader studies, correcting verification bias, and correcting when an imperfect gold standard is used Thoroughly detailed with numerous applications and end-of-chapter problems as well as a related FTP site providing FORTRAN program listings, data sets, and instructional hints, Statistical Methods in Diagnostic Medicine is a valuable addition to the literature of the field, serving as a much-needed guide for both clinicians and advanced students.
Statistical Methods In Diagnostic Medicine 3rd Ed Ition
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Author : Zhou
language : en
Publisher: Wiley-Blackwell
Release Date : 2024-12-19
Statistical Methods In Diagnostic Medicine 3rd Ed Ition written by Zhou and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-19 with categories.
Statistical Methods In Medical Research
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Author : Charan Singh Rayat
language : en
Publisher: Springer
Release Date : 2018-08-23
Statistical Methods In Medical Research written by Charan Singh Rayat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-23 with Medical categories.
This book covers all aspects of statistical methods in detail with applications. It presents solutions to the needs of post-graduate medical students, doctors and basic medical scientists for statistical evaluation of data. In present era, dependency on softwares for statistical analysis is eroding the basic understanding of the statistical methods and their applications. As a result, there are very few basic medical scientists capable of analyzing their research data due to lack of knowledge and ability. This book has been written in systematic way supported by figures and tables for basic understanding of various terms, definitions, formulae and applications of statistical methods with solved examples and graphic presentation of data to create interest in this mathematical science.
Introduction To Statistical Methods In Pathology
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Author : Amir Momeni
language : en
Publisher: Springer
Release Date : 2017-09-07
Introduction To Statistical Methods In Pathology written by Amir Momeni and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-07 with Medical categories.
This text provides a comprehensive and practical review of the main statistical methods in pathology and laboratory medicine. It introduces statistical concepts used in pathology and laboratory medicine. The information provided is relevant to pathologists both for their day to day clinical practice as well as in their research and scholarly activities. The text will begins by explaining the fundamentals concepts in statistics. In the later sections, these fundamental concepts are expanded and unique applications of statistical methods in pathology and laboratory medicine practice are introduced. Other sections of the text explain research methodology in pathology covering a broad range of topics from study design to analysis of data. Finally, data-heavy novel concepts that are emerging in pathology and pathology research are presented such as molecular pathology and pathology informatics. Introduction to Statistical Methods in Pathology will be of great value for pathologists, pathology residents, basic and translational researchers, laboratory managers and medical students.
Essential Statistical Methods For Medical Statistics
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Author : J. Philip Miller
language : en
Publisher: Elsevier
Release Date : 2010-11-08
Essential Statistical Methods For Medical Statistics written by J. Philip Miller and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-08 with Mathematics categories.
Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009). While the use of statistics in these fields has a long and rich history, the explosive growth of science in general, and of clinical and epidemiological sciences in particular, has led to the development of new methods and innovative adaptations of standard methods. This volume is appropriately focused for individuals working in these fields. Contributors are internationally renowned experts in their respective areas. - Contributors are internationally renowned experts in their respective areas - Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research - Methods for assessing Biomarkers, analysis of competing risks - Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs - Structural equations modelling and longitudinal data analysis
Bayesian Biostatistics And Diagnostic Medicine
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Author : Lyle D. Broemeling
language : en
Publisher: CRC Press
Release Date : 2007-07-12
Bayesian Biostatistics And Diagnostic Medicine written by Lyle D. Broemeling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-12 with Mathematics categories.
There are numerous advantages to using Bayesian methods in diagnostic medicine, which is why they are employed more and more today in clinical studies. Exploring Bayesian statistics at an introductory level, Bayesian Biostatistics and Diagnostic Medicine illustrates how to apply these methods to solve important problems in medicine and biology.
Statistical Methods In Diagnostic Medicine
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Author : Xiao-Hua Zhou
language : en
Publisher: John Wiley & Sons
Release Date : 2014-08-21
Statistical Methods In Diagnostic Medicine written by Xiao-Hua Zhou and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-21 with Medical categories.
Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.
The Statistical Evaluation Of Medical Tests For Classification And Prediction
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Author : Margaret Sullivan Pepe
language : en
Publisher: OUP Oxford
Release Date : 2003-03-13
The Statistical Evaluation Of Medical Tests For Classification And Prediction written by Margaret Sullivan Pepe and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-13 with Medical categories.
The use of clinical and laboratory information to detect conditions and predict patient outcomes is a mainstay of medical practice. Modern biotechnology offers increasing potential to develop sophisticated tests for these purposes. This book describes the statistical concepts and techniques for evaluating the accuracy of medical tests. Worked examples include applications to cancer biomarker studies, prospective disease screening studies, diagnostic radiology studies and audiology testing studies. The statistical methodology can be broadly applied for evaluating classifiers and to problems beyond medical settings. Several measures for quantifying test accuracy are described including the Receiver Operating Characteristic Curve. Pepe presents statistical procedures for the estimation and comparison of those measures among tests. Regression frameworks for assessing factors that influence test accuracy and for comparing tests while adjusting for such factors are presented. The sequence of research steps involved in the development of a test is considered in some detail. Sample size calculations and other issues pertinent to study design are described for tests at various phases of development. In addition, the impacts of missing data and imperfect reference data are addressed. These problems often occur in practice, and modern statistical procedures for dealing with them are discussed. Additional topics that are covered include: meta-analysis for summarizing the results of multiple studies of a test; the evaluation of markers for predicting event time data; and procedures for combining the results of multiple tests to improve classification. This book should be of interest to quantitative researchers and practicing statisticians. The book also covers the theoretical foundations for statistical inference and should therefore be of interest to academic statisticians including those involved in statistical methodological research in this field.
Statistical Evaluation Of Diagnostic Performance
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Author : Kelly H. Zou
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Statistical Evaluation Of Diagnostic Performance written by Kelly H. Zou and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Mathematics categories.
Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statistical classifiers, as well as for evaluating predictive models or algorithms. This book presents innovative approaches in ROC analysis, which are releva