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Big Data Analysis For Bioinformatics And Biomedical Discoveries


Big Data Analysis For Bioinformatics And Biomedical Discoveries
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Big Data Analysis For Bioinformatics And Biomedical Discoveries


Big Data Analysis For Bioinformatics And Biomedical Discoveries
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Author : Shui Qing Ye
language : en
Publisher: CRC Press
Release Date : 2016-01-13

Big Data Analysis For Bioinformatics And Biomedical Discoveries written by Shui Qing Ye and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-13 with Computers categories.


Demystifies Biomedical and Biological Big Data AnalysesBig Data Analysis for Bioinformatics and Biomedical Discoveries provides a practical guide to the nuts and bolts of Big Data, enabling you to quickly and effectively harness the power of Big Data to make groundbreaking biological discoveries, carry out translational medical research, and implem



Scalable Big Data Analytics For Protein Bioinformatics


Scalable Big Data Analytics For Protein Bioinformatics
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Author : Dariusz Mrozek
language : en
Publisher: Springer
Release Date : 2018-12-26

Scalable Big Data Analytics For Protein Bioinformatics written by Dariusz Mrozek and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-26 with Computers categories.


This book presents a focus on proteins and their structures. The text describes various scalable solutions for protein structure similarity searching, carried out at main representation levels and for prediction of 3D structures of proteins. Emphasis is placed on techniques that can be used to accelerate similarity searches and protein structure modeling processes. The content of the book is divided into four parts. The first part provides background information on proteins and their representation levels, including a formal model of a 3D protein structure used in computational processes, and a brief overview of the technologies used in the solutions presented in the book. The second part of the book discusses Cloud services that are utilized in the development of scalable and reliable cloud applications for 3D protein structure similarity searching and protein structure prediction. The third part of the book shows the utilization of scalable Big Data computational frameworks, like Hadoop and Spark, in massive 3D protein structure alignments and identification of intrinsically disordered regions in protein structures. The fourth part of the book focuses on finding 3D protein structure similarities, accelerated with the use of GPUs and the use of multithreading and relational databases for efficient approximate searching on protein secondary structures. The book introduces advanced techniques and computational architectures that benefit from recent achievements in the field of computing and parallelism. Recent developments in computer science have allowed algorithms previously considered too time-consuming to now be efficiently used for applications in bioinformatics and the life sciences. Given its depth of coverage, the book will be of interest to researchers and software developers working in the fields of structural bioinformatics and biomedical databases.



Big Data Analytics In Bioinformatics And Healthcare


Big Data Analytics In Bioinformatics And Healthcare
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Author : Baoying Wang
language : en
Publisher:
Release Date : 2014-10

Big Data Analytics In Bioinformatics And Healthcare written by Baoying Wang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10 with Data mining categories.


"This book merges the fields of biology, technology, and medicine in order to present a comprehensive study on the emerging information processing applications necessary in the field of electronic medical record management"--



The Ethics Of Biomedical Big Data


The Ethics Of Biomedical Big Data
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Author : Brent Daniel Mittelstadt
language : en
Publisher: Springer
Release Date : 2016-08-03

The Ethics Of Biomedical Big Data written by Brent Daniel Mittelstadt and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-03 with Philosophy categories.


This book presents cutting edge research on the new ethical challenges posed by biomedical Big Data technologies and practices. ‘Biomedical Big Data’ refers to the analysis of aggregated, very large datasets to improve medical knowledge and clinical care. The book describes the ethical problems posed by aggregation of biomedical datasets and re-use/re-purposing of data, in areas such as privacy, consent, professionalism, power relationships, and ethical governance of Big Data platforms. Approaches and methods are discussed that can be used to address these problems to achieve the appropriate balance between the social goods of biomedical Big Data research and the safety and privacy of individuals. Seventeen original contributions analyse the ethical, social and related policy implications of the analysis and curation of biomedical Big Data, written by leading experts in the areas of biomedical research, medical and technology ethics, privacy, governance and data protection. The book advances our understanding of the ethical conundrums posed by biomedical Big Data, and shows how practitioners and policy-makers can address these issues going forward.



Big Data Analytics In Chemoinformatics And Bioinformatics


Big Data Analytics In Chemoinformatics And Bioinformatics
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Author : Subhash C. Basak
language : en
Publisher: Elsevier
Release Date : 2022-12-06

Big Data Analytics In Chemoinformatics And Bioinformatics written by Subhash C. Basak and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Science categories.


Big Data Analytics in Chemoinformatics and Bioinformatics: With Applications to Computer-Aided Drug Design, Cancer Biology, Emerging Pathogens and Computational Toxicology provides an up-to-date presentation of big data analytics methods and their applications in diverse fields. The proper management of big data for decision-making in scientific and social issues is of paramount importance. This book gives researchers the tools they need to solve big data problems in these fields. It begins with a section on general topics that all readers will find useful and continues with specific sections covering a range of interdisciplinary applications. Here, an international team of leading experts review their respective fields and present their latest research findings, with case studies used throughout to analyze and present key information. - Brings together the current knowledge on the most important aspects of big data, including analysis using deep learning and fuzzy logic, transparency and data protection, disparate data analytics, and scalability of the big data domain - Covers many applications of big data analysis in diverse fields such as chemistry, chemoinformatics, bioinformatics, computer-assisted drug/vaccine design, characterization of emerging pathogens, and environmental protection - Highlights the considerable benefits offered by big data analytics to science, in biomedical fields and in industry



Computational Intelligence And Big Data Analytics


Computational Intelligence And Big Data Analytics
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Author : Ch. Satyanarayana
language : en
Publisher: Springer
Release Date : 2018-09-22

Computational Intelligence And Big Data Analytics written by Ch. Satyanarayana and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-22 with Computers categories.


This book highlights major issues related to big data analysis using computational intelligence techniques, mostly interdisciplinary in nature. It comprises chapters on computational intelligence technologies, such as neural networks and learning algorithms, evolutionary computation, fuzzy systems and other emerging techniques in data science and big data, ranging from methodologies, theory and algorithms for handling big data, to their applications in bioinformatics and related disciplines. The book describes the latest solutions, scientific results and methods in solving intriguing problems in the fields of big data analytics, intelligent agents and computational intelligence. It reflects the state of the art research in the field and novel applications of new processing techniques in computer science. This book is useful to both doctoral students and researchers from computer science and engineering fields and bioinformatics related domains.



Big Data In Omics And Imaging


Big Data In Omics And Imaging
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Author : Momiao Xiong
language : en
Publisher: CRC Press
Release Date : 2017-12-01

Big Data In Omics And Imaging written by Momiao Xiong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Mathematics categories.


Big Data in Omics and Imaging: Association Analysis addresses the recent development of association analysis and machine learning for both population and family genomic data in sequencing era. It is unique in that it presents both hypothesis testing and a data mining approach to holistically dissecting the genetic structure of complex traits and to designing efficient strategies for precision medicine. The general frameworks for association analysis and machine learning, developed in the text, can be applied to genomic, epigenomic and imaging data. FEATURES Bridges the gap between the traditional statistical methods and computational tools for small genetic and epigenetic data analysis and the modern advanced statistical methods for big data Provides tools for high dimensional data reduction Discusses searching algorithms for model and variable selection including randomization algorithms, Proximal methods and matrix subset selection Provides real-world examples and case studies Will have an accompanying website with R code The book is designed for graduate students and researchers in genomics, bioinformatics, and data science. It represents the paradigm shift of genetic studies of complex diseases– from shallow to deep genomic analysis, from low-dimensional to high dimensional, multivariate to functional data analysis with next-generation sequencing (NGS) data, and from homogeneous populations to heterogeneous population and pedigree data analysis. Topics covered are: advanced matrix theory, convex optimization algorithms, generalized low rank models, functional data analysis techniques, deep learning principle and machine learning methods for modern association, interaction, pathway and network analysis of rare and common variants, biomarker identification, disease risk and drug response prediction.



Computational Exome And Genome Analysis


Computational Exome And Genome Analysis
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Author : Peter N. Robinson
language : en
Publisher: CRC Press
Release Date : 2017-09-13

Computational Exome And Genome Analysis written by Peter N. Robinson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-13 with Computers categories.


Exome and genome sequencing are revolutionizing medical research and diagnostics, but the computational analysis of the data has become an extremely heterogeneous and often challenging area of bioinformatics. Computational Exome and Genome Analysis provides a practical introduction to all of the major areas in the field, enabling readers to develop a comprehensive understanding of the sequencing process and the entire computational analysis pipeline.



Application Of Omics Ai And Blockchain In Bioinformatics Research


Application Of Omics Ai And Blockchain In Bioinformatics Research
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Author : Jeffrey J P Tsai
language : en
Publisher: World Scientific
Release Date : 2019-10-14

Application Of Omics Ai And Blockchain In Bioinformatics Research written by Jeffrey J P Tsai and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-14 with Science categories.


With the increasing availability of omics data and mounting evidence of the usefulness of computational approaches to tackle multi-level data problems in bioinformatics and biomedical research in this post-genomics era, computational biology has been playing an increasingly important role in paving the way as basis for patient-centric healthcare.Two such areas are: (i) implementing AI algorithms supported by biomedical data would deliver significant benefits/improvements towards the goals of precision medicine (ii) blockchain technology will enable medical doctors to securely and privately build personal healthcare records, and identify the right therapeutic treatments and predict the progression of the diseases.A follow-up in the publication of our book Computation Methods with Applications in Bioinformatics Analysis (2017), topics in this volume include: clinical bioinformatics, omics-based data analysis, Artificial Intelligence (AI), blockchain, big data analytics, drug discovery, RNA-seq analysis, tensor decomposition and Boolean network.



Python For Bioinformatics


Python For Bioinformatics
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Author : Sebastian Bassi
language : en
Publisher: CRC Press
Release Date : 2017-08-07

Python For Bioinformatics written by Sebastian Bassi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-07 with Science categories.


In today's data driven biology, programming knowledge is essential in turning ideas into testable hypothesis. Based on the author’s extensive experience, Python for Bioinformatics, Second Edition helps biologists get to grips with the basics of software development. Requiring no prior knowledge of programming-related concepts, the book focuses on the easy-to-use, yet powerful, Python computer language. This new edition is updated throughout to Python 3 and is designed not just to help scientists master the basics, but to do more in less time and in a reproducible way. New developments added in this edition include NoSQL databases, the Anaconda Python distribution, graphical libraries like Bokeh, and the use of Github for collaborative development.