Cancer Metastasis And The Lymphovascular System
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Cancer Metastasis And The Lymphovascular System
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Author : Stanley P. L. Leong
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-05
Cancer Metastasis And The Lymphovascular System written by Stanley P. L. Leong and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-05 with Medical categories.
This book details the anatomy and physiology of the lymphovascular system as well as describes the mechanisms of metastasis. It provides readers with an understanding of immune responses of draining lymph nodes against cancer. Coverage also explains the rationale of adopting molecular therapeutics against growth factor receptors, apoptotic factors, signaling pathways and angiogenesis.
Cancer Metastasis Through The Lymphovascular System
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Author : Stanley P. Leong
language : en
Publisher: Springer Nature
Release Date : 2022-06-24
Cancer Metastasis Through The Lymphovascular System written by Stanley P. Leong and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-24 with Medical categories.
This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions.
Cancer Metastasis Through The Lymphovascular System
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Author : S. David Nathanson
language : en
Publisher:
Release Date : 2022
Cancer Metastasis Through The Lymphovascular System written by S. David Nathanson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Cancer categories.
This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. .
From Local Invasion To Metastatic Cancer
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Author : Stanley P. L. Leong
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-09
From Local Invasion To Metastatic Cancer written by Stanley P. L. Leong and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-09 with Medical categories.
In human solid tumors, nodal status is the most important prognostic indicator for patient outcome. Recent developments in the sentinel lymph node concept have resulted in new procedures to define the first draining node as the primary gateway through which the cancer will spread. In From Local Invasion to Metastatic Cancer: Involvement of Distant Sites Through the Lymphovascular System, a panel of international authorities takes an in-depth look at the role of the lymphovascular system in the spread of cancer. The authors summarize the findings of the Second International Symposium on Cancer Metastasis: Basis for Rational Therapy summit. Specifically, the book presents important developments in the biology and clinical understanding of cancer metastasis, describes the relationship between tumor microenvironment and proliferation, and defines the process of lymphangiogenesis and angiogenesis with special reference to cancer metastasis. From Local Invasion to Metastatic Cancer: Involvement of Distant Sites Through the Lymphovascular System provides oncologists, radiologists, and cancer researchers the necessary information to study and develop new strategies to curb the process of metastasis.
Lymphatic Metastasis And Sentinel Lymphonodectomy
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Author : P.M. Schlag
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Lymphatic Metastasis And Sentinel Lymphonodectomy written by P.M. Schlag and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Metastases determine malignancy. The main attention so far has been focused upon organ metastases. The molecular mechanisms thereof, while far from being totally elucidated, are increasingly well understood. Modern diagnostic tools now enable detection and precise localization of small lesions. In contrast, our knowl edge and diagnostic capabilities regarding metastatic spread to the'lymphatic system are rather limited. However, there have re cently been a number of interesting advances. It is the aim of this volume to submit these developments to detailed analysis. The therapeutic relevance of enhanced sensitivity in detection of lymph node metastases has to be considered in the light of in creased morbidity versus eventual prognostic improvements by modification of therapy. An interesting concept which might im prove diagnostic accuracy while reducing operative morbidity is the "sentinel node" technique. Surgical standards are lacking, however, and many fundamental questions pertaining to precise lymphatic mapping remain unanswered. Whether the sentinel node concept is of general relevance or whether it is applicable in only a few organs remains to be determined. This book offers intensive discussion of the concept from methodological and tu mor biological viewpoints. World-renowned experts with long term involvement in related basic and clinical research provide the reader with a broad survey of actual knowledge together with a critical appraisal of recent and future developments. We sincerely hope this book succeeds in providing an outlook as a reference for all clinicians on future prospects and serving and researchers in this extremely important field.
Lymphangiogenesis In Cancer Metastasis
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Author : Steven A. Stacker
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-30
Lymphangiogenesis In Cancer Metastasis written by Steven A. Stacker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-30 with Medical categories.
Lymphangiogenesis and Cancer Metastasis introduces the new field of lymphatic vessel growth and development, and its relationship to the metastatic spread of cancer cells. The book covers all aspects of this new field from the fundamental role that protein growth factors and their receptors play in lymphangiogenesis to the potential application of these advances to cancer diagnosis and treatment. Other clinical aspects explored include the mechanisms and importance of lymph node metastasis, the role of the lymphatics in lymphangioleiomyomatosis and Kaposi’s sarcoma, and approaches for imaging lymphatics in cancer. The book also covers the innovative approaches taken by researchers to explore new roles for lymphatic vessel biology in the context of cancer. The information presented in this volume, which describes the revolutionary concepts of tumor lymphangiogenesis, will be of interest to all students, scientists and oncologists who are seeking to understand the complexities of tumor metastasis. Key Features: Presents fundamental concepts of tumor lymphangiogenesis and the molecules which control this process Provides a comprehensive summary of current research in this ground breaking area Provides a book which links progress in basic tumor and developmental biology with current and future oncology practise Is an essential text for molecular biologists, cell biologists and oncologists seeking to understand the implications of this rapidly developing area.
Lymphatic System Metastasis
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Author : Leonard Weiss
language : en
Publisher:
Release Date : 1980
Lymphatic System Metastasis written by Leonard Weiss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Lymphatic metastasis categories.
Atlas Of Lymphatic System In Cancer
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Author : Shamil Gantsev
language : en
Publisher: Springer Nature
Release Date : 2020-04-01
Atlas Of Lymphatic System In Cancer written by Shamil Gantsev and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-01 with Medical categories.
This atlas contains a large number of original photographs illustrating the anatomy, research methods, and structural features of the structure of the lymphatic apparatus in oncological diseases. The tissue complexes of the axillary region have been studied in detail. The lymphatic maps of the axillary region in cancer are presented, including those with manifestations of lymphangiogenesis; newly formed lymph nodes formed as a result of neolymphogenesis are also considered. Atlas of Lymphatic System in Cancer: Sentinel Lymph Node, Lymphangiogenesis and Neolymphogenesis is intended for oncologists, anatomists, morphologists and doctors of other specialties. The book is the result of ten years of research. The applied technology of ultrasonic isolation of anatomical structures made it possible to take a fresh look at the lymphatic apparatus in cancer and describe the phenomenon of neolymphogenesis.
The Lymphatic System In Colorectal Cancer
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Author : Wim Ceelen
language : en
Publisher: Academic Press
Release Date : 2022-02-11
The Lymphatic System In Colorectal Cancer written by Wim Ceelen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-11 with Science categories.
The Lymphatic System in Colorectal Cancer: Basic Concepts, Pathology, Imaging, and Treatment Perspectives provides an in-depth overview on the role of the lymphatic system in the pathogenesis and treatment of colorectal cancer. This is the first book to provide a comprehensive, multidisciplinary approach to the lymphatic system in colorectal cancer, with topics ranging from cancer biology and mathematical modeling to surgical approaches and novel imaging techniques. This book is valuable for cancer researchers, oncologists and anyone interested in the biology and treatment of colorectal cancer. Bringing together internationally renowned experts, the book's chapters encompass relevant content to help readers understand complex subjects. Lymphatic spread is one of the hallmarks of locally advanced colorectal cancer that adversely affects prognosis. Nevertheless, the molecular pathogenesis, dynamics and prognostic significance of lymphatic spread remain poorly understood. At the same time, novel surgical approaches such as complete mesocolic excision and sentinel node identification are being introduced, but their value remains uncertain. Presents a multidisciplinary approach, allowing readers to identify relevant fields of collaboration and inspire novel research endeavors in the field Discusses novel imaging techniques such as near-infrared that is being introduced in clinical practice as a tool for identifying sentinel nodes and lymphatic pathways Brings together international experts who shed light on the most relevant aspects of lymphatic spread in cancer of the bowel, underlying mechanisms, and the best method to avoid or treat it
The Lymphatic System And Cancer
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Author : John L. Meyer
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1994
The Lymphatic System And Cancer written by John L. Meyer and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Lymphatic metastasis - categories.
We are entering a new era of understanding the lymphatic system brought about by important insights from experimental investigations and clinical trials.