Lymphatic Metastasis And Sentinel Lymphonodectomy
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Lymphatic Metastasis And Sentinel Lymphonodectomy
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Author : P.M. Schlag
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Lymphatic Metastasis And Sentinel Lymphonodectomy written by P.M. Schlag and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Metastases determine malignancy. The main attention so far has been focused upon organ metastases. The molecular mechanisms thereof, while far from being totally elucidated, are increasingly well understood. Modern diagnostic tools now enable detection and precise localization of small lesions. In contrast, our knowl edge and diagnostic capabilities regarding metastatic spread to the'lymphatic system are rather limited. However, there have re cently been a number of interesting advances. It is the aim of this volume to submit these developments to detailed analysis. The therapeutic relevance of enhanced sensitivity in detection of lymph node metastases has to be considered in the light of in creased morbidity versus eventual prognostic improvements by modification of therapy. An interesting concept which might im prove diagnostic accuracy while reducing operative morbidity is the "sentinel node" technique. Surgical standards are lacking, however, and many fundamental questions pertaining to precise lymphatic mapping remain unanswered. Whether the sentinel node concept is of general relevance or whether it is applicable in only a few organs remains to be determined. This book offers intensive discussion of the concept from methodological and tu mor biological viewpoints. World-renowned experts with long term involvement in related basic and clinical research provide the reader with a broad survey of actual knowledge together with a critical appraisal of recent and future developments. We sincerely hope this book succeeds in providing an outlook as a reference for all clinicians on future prospects and serving and researchers in this extremely important field.
The Sentinel Lymph Node Concept
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Author : Alfred Schauer
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-10-28
The Sentinel Lymph Node Concept written by Alfred Schauer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-28 with Medical categories.
The practical application of the sentinel node concept is evaluated in this book. The concept is analyzed for breast cancer, malignant melanoma, tumors of the face, oropharynx, lung, gastrointestinal and urogenital tract. The first part of the book describes the function and use of the nuclear medicine equipment, the tracers used, colloid solutions and modern developments in histological and immunohistochemical lymph node investigations, as well as possible pitfalls. In the second part, specific tumor-related problems are described.
Cancer Metastasis Through The Lymphovascular System
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Author : Stanley P. Leong
language : en
Publisher: Springer Nature
Release Date : 2022-06-24
Cancer Metastasis Through The Lymphovascular System written by Stanley P. Leong and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-24 with Medical categories.
This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions.
Cancer Metastasis And The Lymphovascular System
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Author : Stanley P. L. Leong
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-05
Cancer Metastasis And The Lymphovascular System written by Stanley P. L. Leong and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-05 with Medical categories.
This book details the anatomy and physiology of the lymphovascular system as well as describes the mechanisms of metastasis. It provides readers with an understanding of immune responses of draining lymph nodes against cancer. Coverage also explains the rationale of adopting molecular therapeutics against growth factor receptors, apoptotic factors, signaling pathways and angiogenesis.
Sentinel Lymph Node Biopsy
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Author : Hiram S. Cody
language : en
Publisher: CRC Press
Release Date : 2001-11-08
Sentinel Lymph Node Biopsy written by Hiram S. Cody and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-08 with Medical categories.
An intuitive, ingenious and powerful technique, sentinel lymph node biopsy has entered clinical practice with astonishing rapidity and now represents a new standard of care for melanoma and breast cancer patients, while showing great promise for the treatment of urologic, colorectal, gynecologic, and head and neck cancers. This text, written by international experts in the technique, provides a clear and comprehensive guide, presenting a detailed overview and discussing the various mapping techniques available and how these are applied in a number of leading institutions. This essential resource for surgical onocologists, pathologists, and specialists in nuclear medicine will also provide key information for those planning to start a sentinel lymph node program.
The Sentinel Node In Surgical Oncology
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Author : Mohammad R.S. Keshtgar
language : en
Publisher: Springer
Release Date : 1999
The Sentinel Node In Surgical Oncology written by Mohammad R.S. Keshtgar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
In this volume an account is given of the technologies relevant to the detection of sentinel lymph nodes in the context of surgical oncology. This is a rapidly and evolving field, and the clinical applications discussed in this volume are exciting and important. A multidisciplinary team was assembled to discuss this subject in the light of direct experience gained by each of the groups in the previous 12 months. Clinical case material is presented and the methodology of sentinel lymph node imaging and detection is discussed in detail. The authors have assembled in a single volume a significant amount of personal data and a comprehensive literature review which will serve as a single reference and teaching source for all those interested in this critical technique relevant to the management of large numbers of patients in surgical oncology.
Atlas Of Lymphatic System In Cancer
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Author : Shamil Gantsev
language : en
Publisher: Springer Nature
Release Date : 2020-04-01
Atlas Of Lymphatic System In Cancer written by Shamil Gantsev and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-01 with Medical categories.
This atlas contains a large number of original photographs illustrating the anatomy, research methods, and structural features of the structure of the lymphatic apparatus in oncological diseases. The tissue complexes of the axillary region have been studied in detail. The lymphatic maps of the axillary region in cancer are presented, including those with manifestations of lymphangiogenesis; newly formed lymph nodes formed as a result of neolymphogenesis are also considered. Atlas of Lymphatic System in Cancer: Sentinel Lymph Node, Lymphangiogenesis and Neolymphogenesis is intended for oncologists, anatomists, morphologists and doctors of other specialties. The book is the result of ten years of research. The applied technology of ultrasonic isolation of anatomical structures made it possible to take a fresh look at the lymphatic apparatus in cancer and describe the phenomenon of neolymphogenesis.
Atlas Of Selective Sentinel Lymphadenectomy For Melanoma Breast Cancer And Colon Cancer
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Author : Stanley P. L. Leong
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-10-31
Atlas Of Selective Sentinel Lymphadenectomy For Melanoma Breast Cancer And Colon Cancer written by Stanley P. L. Leong and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-10-31 with Medical categories.
Atlas of Selective Lymphadenectomy for Melanoma, Breast Cancer and Colon Cancer emphasizes a multidisciplinary approach combining the experiences of a nuclear medicine physician, surgeon, and pathologist. This is an important reference also for researchers and clinicians who want to become familiar with sentinel lymph node mapping. The underlying thesis in solid tumor biology is that metastasis in general starts in an orderly progression with lymphatic spread first to the sentinel lymph node (SLN) in the nearest lymph node basin. Therefore, the logical approach is to harvest that specific SLN for thorough analysis.
Cancer Metastasis Through The Lymphovascular System
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Author : S. David Nathanson
language : en
Publisher:
Release Date : 2022
Cancer Metastasis Through The Lymphovascular System written by S. David Nathanson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Cancer categories.
This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. .
The Sentinel Lymph Node Concept In Oncology
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Author : Dieter Ludwig Munz
language : en
Publisher:
Release Date : 2001
The Sentinel Lymph Node Concept In Oncology written by Dieter Ludwig Munz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Lymph nodes categories.