Cardiac Remodeling
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Cardiac Remodeling
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Author : Barry Greenberg
language : en
Publisher: CRC Press
Release Date : 2005-09-29
Cardiac Remodeling written by Barry Greenberg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-29 with Medical categories.
Exploring the causes, mechanisms, and pathophysiology of cardiac remodeling, this reference offers detailed descriptions of the various components of the remodeling process, as well as new therapeutic interventions and recent and future prospects for the treatment of cardiac remodeling.
Cardiac Remodeling And Failure
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Author : Pawan K. Singal
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cardiac Remodeling And Failure written by Pawan K. Singal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
According to the World Health Report (2000 http:/ /www. who. int/whr), of the 55 million deaths worldwide in 1999, more than 16 million were secondary to car diovascular complications. With the prospect of world population increasing from the current level of 6 billion to 9 billion by the middle of this century, the burden of cardiac disease is going to increase astronomically. Furthermore, scientists are being challenged not only to reduce mortality, but also to improve quality of life. Thus, more than ever, intellectuals from different disciplines including biology, sociology, informatics and health care have to join forces to meet the mandate. The World Heart Congress with a focus on "Frontiers in Cardiovascular Health" held in Winnipeg during July 6-11, 2001, made a unique attempt to bring these specialists together to brainstorm and map out the course of action for cardiovascular research and health in the next century. Anytime there is a relative increase in the workload on the heart, there are adap tive myocardial as well as humoral responses. When these adaptations or remodel ing at the organ, subcellular or gene level, become inadequate for a proper tissue perfusion, the condition of heart failure ensues. Prevention of the factors leading to the relative increase in workload as well as a better understanding of the adap tive responses and their failure are some of the hopes to combat the morbidity and mortality due to heart failure.
Cardiac Remodeling New Insights In Physiological And Pathological Adaptations
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Author : Leonardo Roever
language : en
Publisher: Frontiers Media SA
Release Date : 2017-11-15
Cardiac Remodeling New Insights In Physiological And Pathological Adaptations written by Leonardo Roever and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-15 with Electronic book categories.
The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were found to decrease mortality in patients recovering from myocardial infarction. Cardiac remodeling is defined as molecular and interstitial changes, manifested clinically by changes in size, mass , geometry and function of the heart in response to certain aggression. Initially, ventricular remodeling aims to maintain stable cardiac function in situations of aggression.
Cardiac Remodeling
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Author : Bodh I. Jugdutt
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-02-15
Cardiac Remodeling written by Bodh I. Jugdutt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-15 with Medical categories.
The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac remodeling for both the present and future generations of researchers, teachers, students and trainees. This book should stimulate future translational research targeted towards discovery and development for preventing, limiting and reversing bad remodeling over the next few decades, with the ultimate goal of preventing progression to systolic and/or diastolic heart failure. The chapters suggest potential novel strategies that should receive attention for translating basic research knowledge to application in patients at the bedside.
Cellular Molecular And Environmental Contribution In Cardiac Remodeling
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Author : Asim K. Duttaroy
language : en
Publisher: Elsevier
Release Date : 2024-04-16
Cellular Molecular And Environmental Contribution In Cardiac Remodeling written by Asim K. Duttaroy and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-16 with Science categories.
Cellular, Molecular and Environmental Contribution in Cardiac Remodeling: From Lab Bench to Clinical Perspective consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. It extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise and more. This book provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, and its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed. Provides a concise summary of recent developments in cardiac remodeling research, combining novel information and the latest data published in this field Discusses not only cellular and molecular factors impacting cardiac remodeling, but also environmental contributions such as lifestyle and exercise Identifies areas for future research and potential novel strategies for translating basic research knowledge to applications in patients
Cardiac Remodeling
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Author : Jerald Sherman
language : en
Publisher: Nova Science Publishers
Release Date : 2016
Cardiac Remodeling written by Jerald Sherman and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Cardiovascular system categories.
Cardiovascular diseases are the leading cause of death in almost 40% of patients suffering from end stage renal disease (ESRD). Cardiomyopathy and ischemic heart disease are the most frequent causes of cardiac death. The risk of cardiovascular mortality in dialysis patients is 10 to 20 times greater than the general population, particularly in younger patients, taking into account that the relative risk decreases with age. Left ventricular hypertrophy (LVH) is the most common cardiac abnormality in chronic kidney disease (CKD), and the survival risk ratio in such patients is independent. This book examines the molecular mechanisms, treatments and clinical implication of cardiac remodeling. The first chapter discusses risk factors for cardiovascular disease in patients on continuous ambulatory peritoneal dialysis. The following chapters examine the impacts tropomyosin, vitamin D, and coffee have on cardiac remodeling.
Translational Cardiology
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Author : Cam Patterson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-04
Translational Cardiology written by Cam Patterson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-04 with Medical categories.
Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.
Ventricular Geometry In Post Myocardial Infarction Aneurysms
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Author : Srilakshmi Adhyapak
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-05
Ventricular Geometry In Post Myocardial Infarction Aneurysms written by Srilakshmi Adhyapak and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-05 with Medical categories.
The topic of heart failure although extensively researched and reported, has several gray areas. This is especially seen in determining strategies for combating advanced heart failure. The global burden of ischemic heart disease is increasing at an alarming rate to almost pandemic proportions. Even in the presence of state-of the art technology for prompt and successful coronary reperfusion, the population progressing to ischemic cardiomyopathy is substantial. The treatment strategies for ischemic cardiomyopathy do not always ensure optimal clinical results, the reasons for which are varied. The proper patient selection is vital as is the tailoring of suitable therapy. The approach is thus multi-pronged, of which surgical ventricular restoration (SVR) has a definite role. Despite various randomized studies like the STICH-hypothesis 2, where there was a huge selection bias, with patients subjected to an erroneous technique of SVR, with inadequate ventricular remodelling assessment. The present need is to understand the unique anatomy of the left ventricle, its function and perturbations with the onset of heart failure, in order to plan therapeutic strategies to restore near normal anatomy and function. A study of the hemodynamics in ischemic cardiomyopathy is essential, as it differs in certain aspects from other causes of heart failure like idiopathic dilated cardiomyopathy and valvular heart diseases. Since information on these aspects are scattered in various scholarly articles, a concise source in the form of a book would be appropriate and useful for both cardiologists and cardiac surgeons. This project represents a concise review of normal and abnormal cardiac anatomy and physiology, the evolution of SVR to EVLPP with validation of near normal ventricular restoration, plus act as a reference guide for cardiac surgeons with interest in SVR.
Cardiac Vascular Remodeling And Functional Interaction
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Author : Yukio Maruyama
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Cardiac Vascular Remodeling And Functional Interaction written by Yukio Maruyama and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
Cardiac performance is regulated not only by cardiac muscle properties but also by several other factors, including those associated with the neurohumoral system and the mechanical characteristics of the peripheral circulation. New information con cerning these regulatory factors has furthered our understanding of the pathophysi ology of cardiac dysfunction. However, controversy remains, along with a need to integrate these multidisciplinary findings. It was with this in mind, together with my continuing interest in the response of the normal and diseased heart to variations in loading conditions, that the satellite symposium entitled "Interactions Between Car diac Function and Vascular Dynamics" was organized and dedicated to my mentor, Dr. T. Takishima. The symposium was held in Fukushima, Japan, in 1992 following the Tenth Inter national Conference of the Cardiovascular Systems Dynamics Society in Kobe, Japan, which was organized by the then president of the society, Dr. Masatsugu Hori. The Fukushima symposium and the Kobe conference were stimulating and informative. To commemorate these events, Dr. Hori, Dr. Janicki, and I decided to publish this book. It covers topics that were presented then as well as pertinent new material. As a result, the book includes not only updated reviews but also up-to-date findings that were not considered at the two scientific sessions. The high level attained in this book is due to the outstanding contributions from internationally renowned scientists. This final product of their efforts should prove to be a valuable source of information to the reader.
Myocardial Preservation
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Author : Dennis V. Cokkinos
language : en
Publisher: Springer
Release Date : 2019-01-28
Myocardial Preservation written by Dennis V. Cokkinos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-28 with Medical categories.
This timely book reveals an integrated approach to myocardial preservation focusing on translational research and clinical applications. Chapters cover both the mechanisms of heart failure in addition to therapeutic considerations, including forms of cardiac cell death, cardiac remodelling and cardiac regeneration. Potential future research directions are also proposed, enabling the reader to gain a broad in-depth understanding of the topic. Myocardial Preservation: Translational Research and Clinical Application presents a thorough review of myocardial preservation. Its comprehensive approach provides a valuable reference for cardiology researchers and practising and trainee cardiologists seeking new insight to the topic.