Cell Cycle Effects Of Drugs
DOWNLOAD
AUDIOBOOK
READ ONLINE
Download Cell Cycle Effects Of Drugs PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Cell Cycle Effects Of Drugs book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Cell Cycle Effects Of Drugs
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Lyle A. Dethlefsen
language : en
Publisher: Pergamon
Release Date : 1986
Cell Cycle Effects Of Drugs written by Lyle A. Dethlefsen and has been published by Pergamon this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.
An understanding of the mechanism of action of anticancer agents depends on investigations into the cell cycle effects of these agents. The intent of this volume is to review our current knowledge about these basic cell cycle effects and suggest what directions future investigations should take. Chapters 1 and 2 are general, basic chapters dealing with the biology of the cell cycle per se and quantitative cytokinetics (techniques) respectively. The remaining nine chapters each cover a specific anticancer compound as examples of various classes of anticancer agents. In bringing this information together for the first time this volume represents a major step in the understanding of the mechanisms that are involved in the treatment of cell cycle disorders.
Drugs And The Cell Cycle
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : A Zimmerman
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Drugs And The Cell Cycle written by A Zimmerman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
Drugs and the Cell Cycle provides an introduction to fundamental principles and studies on the mechanisms of drug action on proliferating cells. The book is intended to reduce the time lag between observation and practical application. Comprised of 10 chapters, the book describes the plant alkaloids, alkylating agents, mercurials, adrenergic agents, radiomimetics, narcotics, hallucinogens, mitogens, hepatotoxins, antiobiotics, and antimetabolites of various types. The text also emphasizes the drugs used in cancer chemotherapy, and the in vitro and in vivo cell systems of bacteria, protozoa, sea urchins, and mammals. The concepts are presented with comprehensive illustrations and tables to help readers obtain more efficient understanding and learning. The information and concepts presented in this volume will be of great interest to scientists and students in many disciplines, including physiology, pharmacology, and oncology, as well as cellular, molecular, and developmental biology. The book will also fill the gap between drug experimental observations and their potential relevance to man.
Effects Of Drugs On The Cell Nucleus
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Harris Busch
language : en
Publisher:
Release Date : 1979
Effects Of Drugs On The Cell Nucleus written by Harris Busch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Antineoplastic agents categories.
Cell Cycle Inhibitors In Cancer Therapy
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Antonio Giordano
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-11-20
Cell Cycle Inhibitors In Cancer Therapy written by Antonio Giordano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-20 with Medical categories.
Leading clinicians and investigators review in a comprehensible and user-friendly style all the latest information about the molecular biology of cell cycle control and demonstrate its clinical relevance to understanding neoplastic diseases. Topics range from Cdk inhibitors and cell cycle regulators to the prognostic value of p27 and tumor suppressor genes as diagnostic tools. Actual case studies show how the new molecular understanding has produced such drugs as Flavopiridol and Sulindac. The book brings all the recent critical research findings to bear on clinical practice, and clearly shows their powerful impact on the diagnostics, prognostics, and therapeutics of cancer, AIDS, and cardiovascular disease.
The Cell Cycle
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : David Owen Morgan
language : en
Publisher: New Science Press
Release Date : 2007
The Cell Cycle written by David Owen Morgan and has been published by New Science Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Science categories.
Cell division is a central biological process: it yields the cells required for development and growth, and supplies the replacement cells to repair and maintain old or damaged tissue. This book gives the students a complete overview of the process of cell division - from chromosome division, through mitosis, cytokinesis, and meiosis.
Cell Cycle Deregulation In Cancer
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Greg H. Enders
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10
Cell Cycle Deregulation In Cancer written by Greg H. Enders and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Medical categories.
Cancer is fundamentally a disease of abnormal cell proliferation: Cancer cells multiply when and where they should not. This proliferation entails escape from normal bounds imposed by the tissue environment, the internal biology of the cell (DNA damage, chromosomal imbalances, disorganized mitotic spindles), and the proliferative history of the cell (normal generational times). Some of the key oncogenic events in cancer directly perturb proteins that regulate progression through the cell division cycle, others alter cell cycle progression indirectly, through effects on signaling pathway that impinge on the cell cycle. This biology is fundamentally important in cancer therapy. Many of the workhorse treatments for cancer rely on killing proliferating cells. Furthermore, there is growing recognition that stem cell-transit amplifying cell hierarchies may persist or be generated during tumorigenesis, generating important functional heterogeneity in cell cycle control among tumor cells, with far-reaching scientific and clinical implications. This volume outlines major cell cycle perturbations that drive tumorigenesis and considers the prospects for using such knowledge in cancer therapy.
Cell Cycle Control
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Tim Humphrey
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
Cell Cycle Control written by Tim Humphrey and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.
The fundamental question of how cells grow and divide has perplexed biologists since the development of the cell theory in the mid-19th century, when it was recognized by Virchow and others that “all cells come from cells.” In recent years, considerable effort has been applied to the identification of the basic molecules and mechanisms that regulate the cell cycle in a number of different organisms. Such studies have led to the elucidation of the central paradigms that underpin eukaryotic cell cycle control, for which Lee Hartwell, Tim Hunt, and Paul Nurse were jointly awarded the Nobel Prize for Medicine and Physiology in 2001 in recognition of their seminal contributions to this field. The importance of understanding the fundamental mechanisms that modulate cell division has been reiterated by relatively recent discoveries of links between cell cycle control and DNA repair, growth, cellular metabolism, development, and cell death. This new phase of integrated cell cycle research provides further challenges and opportunities to the biological and medical worlds in applying these basic concepts to understanding the etiology of cancer and other proliferative diseases.
Anticancer Drug Development
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Bruce C. Baguley
language : en
Publisher: Elsevier
Release Date : 2001-11-17
Anticancer Drug Development written by Bruce C. Baguley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-17 with Medical categories.
Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. One work that can be consulted for all aspects of anticancer drug development Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques Hundreds of references that allow the reader to access relevant scientific and medical literature Clear illustrations, some in color, that provide both understanding of the field and material for teaching
Cell Cycle And Growth Control
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Gary S. Stein
language : en
Publisher: John Wiley & Sons
Release Date : 2004-05-24
Cell Cycle And Growth Control written by Gary S. Stein and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-05-24 with Science categories.
This comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more.
The Cell Cycle
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Valerie W. Hu
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Cell Cycle written by Valerie W. Hu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Interest in the cell cycle has grown explosively in recent years as a result of the identification of key cell cycle regulators and their substrates. Aside from enhancing our understanding of normal cellular growth controls, this new knowledge has also becn valuable in elucidating mechanisms of growth deregulation which occur in diseased states, such as cancer and, in some instances, viral or parasitic infections. The Thirteenth Washington International Spring Symposium was organized with the intention of bringing together scientists working on different aspects of the cell cycle. Scientific topics presented ranged from molecular regulators and effectors to mitosis specific changes in cell architecture to the role of the cell cycle in development and disease. The goal of this gathering was to help formulate a more comprehensive and integrated picture of events driving and being driven by the cell cycle, as well as to evaluate the possibilities for clinical application of this knowledge. This symposium, held in Washington, D.C. from May 10-14, 1993, was attended by more than 400 scientists from 20 countries, including many of the scientific leaders in this field. This volume contains most of the papers presented at the seven plenary sessions in addition to selected contributions from a total of nine special oral and poster sessions.