Cell Death Regulatory Functions In Hair Follicle Regeneration
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Cell Death Regulatory Functions In Hair Follicle Regeneration
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Author : Giada Mantellato
language : en
Publisher:
Release Date : 2022*
Cell Death Regulatory Functions In Hair Follicle Regeneration written by Giada Mantellato and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022* with categories.
Hair Follicle Regeneration
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Author : Francisco Jimenez
language : en
Publisher: Springer Nature
Release Date : 2022-06-03
Hair Follicle Regeneration written by Francisco Jimenez and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-03 with Science categories.
This book aims to comprehensively review the current cell-based strategies under investigation to achieve the regeneration of human hair follicles. The unique capacity of the human hair follicle to self-renew explains why this complex “mini-organ” has always attracted so much interest as a model for researchers to study stem cell biology and regenerative medicine. The hair follicle is considered a main reservoir of cutaneous stem cells, containing several pools of epithelial, melanocyte, and mesenchymal stem cells involved in hair follicle self-regeneration and pigmentation. In addition, while some of the different follicular cell types contribute to hair shaft growth, others participate in very important interfollicular functions such as dermal remodeling, re-epithelialization after wounding, and cutaneous stem cell homeostasis. The idea of human hair follicle regeneration either “de novo” or by activating dormant miniaturized follicles is not new, yet still continues to arouse enormous interest in the pursuit of a definitive cure for baldness. In contrast to hair follicle regeneration in mice, the attempts made with human follicles have been disappointing in terms of efficiency. However, recent advances in stem cell biology—as well as the appearance of new technologies like 3D printing—have revived expectations in this field of research. This book is divided into four sections. The first part includes an overview of the strategies used in hair follicle regeneration and a historical summary of the most important achievements to date. Parts two and three comprise the main body of the book, with detailed descriptions of the cells and tissue structures involved in hair follicle regeneration, followed by an elaboration of the different therapeutic strategies, engineering techniques, and a clinician’s perspective of stem cell-based therapies in hair loss treatments. Finally, the fourth part reviews the important contribution of the hair follicle in healing cutaneous wounds through the regeneration and remodeling of the dermis and epidermis after injury, as well as wound induced hair follicle neogenesis that occurs when the skin is injured.
Cell Engineering And Regeneration
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Author : Heinz Redl
language : en
Publisher: Springer
Release Date : 2017-02-16
Cell Engineering And Regeneration written by Heinz Redl and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-16 with Technology & Engineering categories.
This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
Hair Growth And Disorders
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Author : Ulrike Blume-Peytavi
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-06-26
Hair Growth And Disorders written by Ulrike Blume-Peytavi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-26 with Medical categories.
Hair disorders have become a central social and psychological issue and patients now have increasing demands and expectations. Written by world-renowned experts, this lavishly illustrated book provides the latest scientific aspects of hair biology, up to date knowledge on hair diagnosis and treatment options as well as hair removal and restoration techniques. The content is divided into three sections: basic aspects of hair growth; hair and scalp disorders; and fotoepilation, surgery and hair cosmetics. In addition, coverage is enhanced with unique sections on hair in different ages and in art, on ethnic hair and in forensic investigations.
Morphogenesis Of Skin
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Author : Sengel
language : en
Publisher: CUP Archive
Release Date : 1976
Morphogenesis Of Skin written by Sengel and has been published by CUP Archive this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Medical categories.
Hair And Scalp Disorders
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Author : Zekayi Kutlubay
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-05-03
Hair And Scalp Disorders written by Zekayi Kutlubay and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-03 with Medical categories.
This textbook contains the latest advances and scientific knowledge from the leading experts in hair biology, hair disorders, and clinical trichology. The book consists of ten sections in which hair biology, hair genetics, hair diagnostics, hair loss types, pathogenesis, treatment options, and restoration techniques are discussed. This book also emphasizes on various genetic and nongenetic alopecia types, differential diagnosis, and the measurement of hair loss. One chapter of the book is devoted to natural products for hair care and treatment. We believe that this textbook will serve as a comprehensive guide to many physicians dealing with hair disorders in their clinical practice.
Epigenetic Regulation Of Skin Development And Regeneration
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Author : Vladimir A. Botchkarev
language : en
Publisher: Springer
Release Date : 2018-09-03
Epigenetic Regulation Of Skin Development And Regeneration written by Vladimir A. Botchkarev and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Science categories.
This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
Macrophages Biology And Role In The Pathology Of Diseases
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Author : Subhra K. Biswas
language : en
Publisher: Springer
Release Date : 2014-11-12
Macrophages Biology And Role In The Pathology Of Diseases written by Subhra K. Biswas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-12 with Medical categories.
Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to tissue micro environmental cues by polarizing to distinct phenotypes, depending on the functions they need to perform. Indeed, functional diversity and plasticity are hallmarks of these cells. Macrophages may also play a detrimental role. An overwhelming body of literature has indicated their crucial role in pathogenesis. The list includes sepsis, cancer, metabolic syndrome, immunodeficiency, auto-immune disease-virtually impacting every major pathology that we know. These observations have suggested macrophages and their related molecules as potential targets in therapeutic applications. Available evidence proclaims macrophages as a key player in homeostasis, host defense and disease. Crucial developments in the past few years call for a re-evaluation and update of our understanding of macrophages. The present book is an endeavour that attempts provide state-of-the art knowledge of these cells in health and disease.
Gene And Cell Therapy
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Author : Nancy Smyth Templeton
language : en
Publisher: CRC Press
Release Date : 2015-01-20
Gene And Cell Therapy written by Nancy Smyth Templeton and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-20 with Science categories.
The Most Comprehensive, State-of-the-Art Book on Using Gene and Cell Therapy in Clinical MedicineGene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fourth Edition presents extensive background and basic information, state-of-the-art technologies, important achievements, and lingering challenges in the fields of gene and cell therapies. T
Cytoskeletal Membrane Interactions And Signal Transduction
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Author : Pam Cowin
language : en
Publisher: Landes Bioscience
Release Date : 1997
Cytoskeletal Membrane Interactions And Signal Transduction written by Pam Cowin and has been published by Landes Bioscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Cell junctions categories.