Cellular And Molecular Mechanisms Underlying Higher Neural Functions
DOWNLOAD
Download Cellular And Molecular Mechanisms Underlying Higher Neural Functions PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Cellular And Molecular Mechanisms Underlying Higher Neural Functions book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Cellular And Molecular Mechanisms Underlying Higher Neural Functions
DOWNLOAD
Author : A. I. Selverston
language : en
Publisher:
Release Date : 1994-06-30
Cellular And Molecular Mechanisms Underlying Higher Neural Functions written by A. I. Selverston and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-06-30 with Medical categories.
Despite the remarkable advances made in molecular neurobiology over the last ten years, very little progress has been made towards understanding how the brain performs higher functions: cognition, behavior, learning, and memory. One of the greatest challenges facing modern neurobiology, therefore, is the integration of data that comes from disparate levels of analysis. This volume presents the results of the Dahlem conference convened to address these issues. The purpose of the conference was to bring together brain researchers, who approach their work at different conceptual levels, to consider how their results might be synthesized into a more integrated view of how the brain works. To try and accomplish this, two specific examples were chosen: the modulation of neural circuits and the phenomena of long-term potentiation (LTP). Neuromodulation has been studied from the molecular to the behavioral level with dramatic breakthroughs at the circuit level over the last five years. Due to the possibility that it may be the cellular mechanism for certain types of learning and memory, LTP has also been studied at different levels. To assist in understanding LTP and neuromodulation at the molecular, cellular, circuit, and behavioral levels, the background papers written for the meeting are included in this volume. The conference itself was devoted to discussing LTP and neuromodulation from the perspective of each of the different levels, and the results of these discussions are presented in the group reports. Particular emphasis was given to a consideration of how the rapid progress in molecular and cellular neurobiology can be integrated into systems and behavioral neurobiology. Specific suggestions for future research in both areas were discussed thoroughly. This volume presents what is most probably the most authoritative, up-to-date assessment of LTP and neuromodulation currently available. Goal of this Dahlem Workshop: to apply new cellular and molecular concepts to the understanding of plasticity in synapses, cells, local circuits, and defined systems in the mature brain.
Cellular And Molecular Mechanisms Of Neurotrophin Function In The Nervous System
DOWNLOAD
Author : Pedro Bekinschtein
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-15
Cellular And Molecular Mechanisms Of Neurotrophin Function In The Nervous System written by Pedro Bekinschtein and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-15 with categories.
Mechanisms Of Memory
DOWNLOAD
Author : J. David Sweatt
language : en
Publisher: Academic Press
Release Date : 2019-08
Mechanisms Of Memory written by J. David Sweatt and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08 with Medical categories.
Mechanisms of Memory, Third Edition, is the only available comprehensive overview of the cellular and molecular mechanisms underlying higher-order learning and memory. Focusing on mechanisms relevant to hippocampus-dependent memory formation, the book progresses systematically from behavior to cellular physiology at molecular and genetic levels. Moreover, it integrates modern discoveries concerning learning and memory disorders, from inherited disorders, to aging and psychiatric disorders. The book emphasizes results from the cutting-edge of contemporary methodologies, such as genetic engineering, molecular biology, complex behavioral characterization, cellular physiology, epigenetics and molecular structure. This updated edition has been expanded to include eight new chapters covering the role of the prefrontal cortex in short-term and working memory, recent discoveries regarding the CNS dopamine system and its implications for reward-based learning, glial cell function in memory formation, the role of altered protein synthesis in long-term memory formation, AMPA receptor trafficking and regulation, and the role of epigenetics in memory formation. This new release continues to be the standard work on all aspects of learning and memory. As such, it is essential reading for students and researchers alike. Presents a unified view of memory mechanisms, from behavior to genes Discusses clinically relevant memory disorders in the context of modern molecular research Provides numerous practical examples on how to implement a research program in the learning and memory area Offers a balanced treatment of the strengths and weaknesses inherent in modern experimental design Emphasizes hippocampus-dependent memory formation while also drawing examples from many different brain regions, types of learning, and various animal model systems
Translational Research In Traumatic Brain Injury
DOWNLOAD
Author : Daniel Laskowitz
language : en
Publisher: CRC Press
Release Date : 2015-12-01
Translational Research In Traumatic Brain Injury written by Daniel Laskowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-01 with Medical categories.
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.
Molecular Mechanisms Of Neural Development And Insights Into Disease
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2021-03-09
Molecular Mechanisms Of Neural Development And Insights Into Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-09 with Science categories.
Neural Development and Disease, Volume 142 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters by one or more members of an international board of authors. Sections in this new release cover The role of primary cilia in neural development and disease, Mechanisms of axon guidance receptor regulation and signaling, Synaptic recognition molecules in development and disease, The regulation of cortical neurogenesis, Axon guidance in the developing spinal cord, The role of astrocytes in synapse formation and maturation, Development of motor circuits, Molecular mechanisms that mediate dendrite morphogenesis, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series
Neural Circuit Development And Function In The Healthy And Diseased Brain
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2013-05-06
Neural Circuit Development And Function In The Healthy And Diseased Brain written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-06 with Science categories.
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 3 sections include coverage of: mechanisms that control the assembly of neural circuits in specific regions of the nervous system, multiple aspects of cognitive development, and disorders of the nervous system arising through defects in neural development
From Neuron To Brain
DOWNLOAD
Author : John G. Nicholls
language : en
Publisher: Sinauer Associates, Incorporated
Release Date : 1992
From Neuron To Brain written by John G. Nicholls and has been published by Sinauer Associates, Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.
From Neuron to Brain, Fourth Edition describes how nerve cells go about their business of transmitting signals, how the signals are put together, and how, out of this integration, higher functions emerge. The emphasis, as before, is on experiments, and on the way they are carried out. Elements of format and presentation have been changed -- more headings have been introduced, the paragraphs are shorter, and the illustrations, now in full color, have been clarified. Intended for use in upper-level undergraduate, graduate, psychology, and medical school neuroscience courses, this book will be of interest to anyone who is curious about the workings of the nervous system.
Cellular And Molecular Mechanisms In Pathogenesis Of Multiple Sclerosis
DOWNLOAD
Author : Edwin Wan
language : en
Publisher: MDPI
Release Date : 2020-11-25
Cellular And Molecular Mechanisms In Pathogenesis Of Multiple Sclerosis written by Edwin Wan and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Science categories.
Multiple sclerosis (MS) is one of the most common neurological disorders in young adults. The etiology of MS is not known, but it is generally accepted that it is autoimmune in nature. Our knowledge of the pathogenesis of MS has increased tremendously in the past decade through clinical studies and the use of experimental autoimmune encephalomyelitis (EAE), a model that has been widely used for MS research. Major advances in the field, such as understanding the roles of pathogenic Th17 cells, myeloid cells, and B cells in MS/EAE, as well as cytokine and chemokine signaling that controls neuroinflammation, have led to the development of potential and clinically approved disease-modifying agents (DMAs). There are many aspects related to the initiation, relapse and remission, and progression of MS that are yet to be elucidated. For instance, what are the genetic and environmental risk factors that promote the initiation of MS, and how do these factors impact the immune system? What factors drive the progression of MS, and what are the roles of peripheral immune cells in disease progression? How do the CNS-infiltrated immune cells interact with the CNS-resident glial cells when the disease progresses? What is the role of microbiome in MS? Can we develop animal models that better represent subcategories of MS? Understanding the cellular and molecular mechanisms that govern the pathogenesis of MS will help to develop novel and more specific therapeutic strategies that will ultimately improve clinical outcomes of the treatments. This Special Issue of Cells has published original research articles, a retrospective clinical report, and review articles that investigate the cellular and molecular basis of MS.
A History Of Nerve Functions
DOWNLOAD
Author : Sidney Ochs
language : en
Publisher: Cambridge University Press
Release Date : 2004-04-19
A History Of Nerve Functions written by Sidney Ochs and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-19 with Science categories.
Recent developments have extended our knowledge of the basic functions of nerves: notably, the demonstration of the mechanism within nerve fibers which transports a wide range of essential materials. In order to understand how this discovery occurred, it is necessary to examine its history. The story begins in ancient Greece when nerves were conceived of as channels through which animal spirits carried sensory impressions to the brain. As science developed, the discoveries of various physical and chemical agents supplanted the agency of animal spirits until the molecular machinery of transport was recognized. In this fascinating and complete history, Sidney Ochs begins with a chronological look at this path of discovery, followed in the second half by a thematic approach wherein the author describes the electrical nature of the nerve impulse, fiber form and its changes in degeneration and regeneration, reflexes, learning, memory and other higher functions in which transport participates.
Cellular And Molecular Mechanisms Underlying Brain Plasticity After Stroke In Animal Model
DOWNLOAD
Author : Ana-Maria Bugă
language : en
Publisher:
Release Date : 2008
Cellular And Molecular Mechanisms Underlying Brain Plasticity After Stroke In Animal Model written by Ana-Maria Bugă and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.