Cellular And Molecular Mechanisms Underlying Higher Neural Functions

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Cellular And Molecular Mechanisms Underlying Higher Neural Functions
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Author : A. I. Selverston
language : en
Publisher:
Release Date : 1994-06-30
Cellular And Molecular Mechanisms Underlying Higher Neural Functions written by A. I. Selverston and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-06-30 with Medical categories.
Despite the remarkable advances made in molecular neurobiology over the last ten years, very little progress has been made towards understanding how the brain performs higher functions: cognition, behavior, learning, and memory. One of the greatest challenges facing modern neurobiology, therefore, is the integration of data that comes from disparate levels of analysis. This volume presents the results of the Dahlem conference convened to address these issues. The purpose of the conference was to bring together brain researchers, who approach their work at different conceptual levels, to consider how their results might be synthesized into a more integrated view of how the brain works. To try and accomplish this, two specific examples were chosen: the modulation of neural circuits and the phenomena of long-term potentiation (LTP). Neuromodulation has been studied from the molecular to the behavioral level with dramatic breakthroughs at the circuit level over the last five years. Due to the possibility that it may be the cellular mechanism for certain types of learning and memory, LTP has also been studied at different levels. To assist in understanding LTP and neuromodulation at the molecular, cellular, circuit, and behavioral levels, the background papers written for the meeting are included in this volume. The conference itself was devoted to discussing LTP and neuromodulation from the perspective of each of the different levels, and the results of these discussions are presented in the group reports. Particular emphasis was given to a consideration of how the rapid progress in molecular and cellular neurobiology can be integrated into systems and behavioral neurobiology. Specific suggestions for future research in both areas were discussed thoroughly. This volume presents what is most probably the most authoritative, up-to-date assessment of LTP and neuromodulation currently available. Goal of this Dahlem Workshop: to apply new cellular and molecular concepts to the understanding of plasticity in synapses, cells, local circuits, and defined systems in the mature brain.
Neural Plasticity And Memory
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Author : Federico Bermudez-Rattoni
language : en
Publisher: CRC Press
Release Date : 2007-04-17
Neural Plasticity And Memory written by Federico Bermudez-Rattoni and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-17 with Psychology categories.
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Bioengineering Approaches To Pulmonary Physiology And Medicine
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Author : M.C.K. Khoo
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-20
Bioengineering Approaches To Pulmonary Physiology And Medicine written by M.C.K. Khoo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-20 with Technology & Engineering categories.
As the current millennium steams towards a close, one cannot help but look with amazement at the incredible amount of progress that has been achieved in medicine in just the last few decades. A key contributing factor to this success has been the importation and blending of ideas and techniques from disciplines outside the traditional borders of medical science. In recent years, the most well-known example is the cross-pollination between molecular biology and medicine. Advances driven by this potent combination have spawned the vision of a future where cures based on gene therapy become commonplace. Yet, as we continue our search for "magic bullets" in the quest to eradicate disease, it important to recognize the value of other less-heralded interdisciplinary efforts that have laid a large part of the foundation of present-day medicine. In pulmonary medicine, the contribution from the bioengineers (a diverse collection of individuals cross-bred to various degrees in mathematical modeling and experimental physiology) has been larger and more sustained than in many other medical specialties. It is easy to point to the vast array of ventilators, blood-gas analyzers, oximeters, pulmonary function devices, and respiration monitors that are present in any modern clinical setting as solid evidence of the successful synergy between engineering science and pulmonary medicine. However, one must not forget the less tangible, but perhaps more important, contributions that have been derived from mathematical modeling and computer simulation, without which many of these modern instruments would not have come into existence.
Translational Research In Traumatic Brain Injury
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Author : Daniel Laskowitz
language : en
Publisher: CRC Press
Release Date : 2016-04-21
Translational Research In Traumatic Brain Injury written by Daniel Laskowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Medical categories.
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Neural Network Models Of Cognition
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Author : J.W. Donahoe
language : en
Publisher: Elsevier
Release Date : 1997-09-26
Neural Network Models Of Cognition written by J.W. Donahoe and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-09-26 with Computers categories.
This internationally authored volume presents major findings, concepts, and methods of behavioral neuroscience coordinated with their simulation via neural networks. A central theme is that biobehaviorally constrained simulations provide a rigorous means to explore the implications of relatively simple processes for the understanding of cognition (complex behavior). Neural networks are held to serve the same function for behavioral neuroscience as population genetics for evolutionary science. The volume is divided into six sections, each of which includes both experimental and simulation research: (1) neurodevelopment and genetic algorithms, (2) synaptic plasticity (LTP), (3) sensory/hippocampal systems, (4) motor systems, (5) plasticity in large neural systems (reinforcement learning), and (6) neural imaging and language. The volume also includes an integrated reference section and a comprehensive index.
The Lifespan Development Of Individuals
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Author : David Magnusson
language : en
Publisher: Cambridge University Press
Release Date : 1997-10-28
The Lifespan Development Of Individuals written by David Magnusson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-28 with Health & Fitness categories.
A full understanding of the developmental process in individuals requires contributions from disciplines including developmental biology and psychology, physiology, neuropsychology, social psychology, sociology, and anthropology. This ambitious and wide-ranging book integrates the findings from these and related areas to form a holistic view of human development from conception to death. Distinguished scientists have combined their expertise in a synthesis of biological and social sciences that will demand the attention of all researchers and practitioners concerned with human development across the lifespan. Based on a Nobel symposium, the topics discussed range from the function and development of single cells to the whole organism interacting with its environment. Drawing upon new theories and models, including the study of nonlinear dynamic systems and chaos theory, this book represents a major step in the move towards an integrated science of human development.
Brain Theory
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Author : Adrianus Aertsen
language : en
Publisher: Elsevier
Release Date : 1996
Brain Theory written by Adrianus Aertsen and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Computers categories.
Hardbound. The present collection of papers focuses on the subject of vision. The papers bring together new insights and facts from various branches of experimental and theoretical neuroscience. The experimental facts presented in the volume stem from disparate fields, such as neuroanatomy, electrophysiology, optical imaging and psychophysics. The theoretical models in part are unsophisticated, yet still inspiring, while others skilfully apply advanced mathematical reasoning to results of experimental measurements. The book is the fifth in a series of volumes intending to define a theory of the brain by bringing together formal reasoning and experimental facts. The reader is thus being introduced to a new kind of brain science, where facts and theory are beginning to blend together.
Neurobiology Of Learning And Memory
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Author : Joe L. Martinez Jr.
language : en
Publisher: Elsevier
Release Date : 1998-06-29
Neurobiology Of Learning And Memory written by Joe L. Martinez Jr. and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-06-29 with Science categories.
Neurobiology of Learning and Memory provides an excellent overview of current information on this fast-growing field of neurobiology. The contents have been structured for use as a course text or as a handy resource for researchers in neuro- and cognitive psychology. It discusses learning and memory from developmental, pharmacological, and psychobiological perspectives, as well as changes in learning and memory with age. Neurobiology of Learning and Memory also includes research on invertebrates and vertebrates, presenting basics in anatomy and development along with computational models. It is written in an easy-to-follow format with summaries at the end of each chapter.Key Features* Provides an overview of information on the neurobiology of learning and memory* Discusses learning and memory from developmental, pharmacological, and psychobiological perspectives, and changes in learning and memory with age* Includes research on invertebrates and vertebrates* Gives basics on anatomy and development* Written for easy comprehension with chapter summaries
The Neuron
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Author : Irwin B. Levitan
language : en
Publisher: Oxford University Press, USA
Release Date : 2002
The Neuron written by Irwin B. Levitan and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.
Molecular Mechanisms Of Neuronal Responsiveness
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Author : Yigal H. Ehrlich
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-13
Molecular Mechanisms Of Neuronal Responsiveness written by Yigal H. Ehrlich and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-13 with Science categories.
The interaction of neurotransmitters, neuromodulators and neuroactive drugs with receptors localized at the cell surface initiates a chain of molecular events leading to integrated neuronal responses to the triggering stimuli. Major advancements in the characterization and isolation of recep tor molecules have answered many quest ions regarding the nature of the ele ments that determine the specificity in these interactions. At the same time, recent studies have provided evidence that delicate regulation by intracellular enzymatic systems determines the efficiency of the stimulus response coupling process, mediates the interaction between receptors, operates in feedback control mechanisms and transduces signals from the receptors to various effector sites in a highly coordinated fashion. These studies are at the focus of the present volume, which is an outcome of a symposium held at the University of Vermont College of Medicine on March 21-23, 1986, in conjunction with the seventeenth annual meeting of the Amer ican Society for Neurochemistry. The symposium has demonstrated clearly that the concerted efforts of investigators in neurophysiology, biochemis try, pharmacology, cell-biology, molecular genetics, neurology, and psy chiatry are required to achieve better understanding of the processes under lying neuronal responsiveness. This volume includes contributions provided by prominent investigators in all these research areas. We hope that the readers will find here a useful source of information and ideas for stimu lating further studies which may serve to narrow the gap between basic neuroscience research and its clinical implications.