Clinical Challenges In Therapeutic Drug Monitoring
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Clinical Challenges In Therapeutic Drug Monitoring
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Author : William Clarke
language : en
Publisher: Elsevier
Release Date : 2016-07-21
Clinical Challenges In Therapeutic Drug Monitoring written by William Clarke and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-21 with Medical categories.
Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations. Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window
Therapeutic Drug Monitoring
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Author : Amitava Dasgupta
language : en
Publisher: Academic Press
Release Date : 2012-06-07
Therapeutic Drug Monitoring written by Amitava Dasgupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-07 with Medical categories.
Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential resource on the current practice of therapeutic drug monitoring in improving patient safety. Includes both the technical and clinical issues associated with therapeutic drug monitoring Discusses the utility of therapeutic drug monitoring of newer drugs such as antiretroviral agents, anticonvulsants, antidepressants etc. Provides up-to-date information on issues in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants Covers important content on the limitations of commercially available immunoassays (chemical tests) for therapeutic drug monitoring and additional analytical techniques
Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology
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Author : Seth Kwabena Amponsah
language : en
Publisher: Springer Nature
Release Date : 2022-10-25
Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology written by Seth Kwabena Amponsah and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-25 with Medical categories.
This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges
Interpretations In Therapeutic Drug Monitoring
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Author : Daniel M. Baer
language : en
Publisher:
Release Date : 1981
Interpretations In Therapeutic Drug Monitoring written by Daniel M. Baer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Medical categories.
Therapeutic Drug Monitoring
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Author : Gerald E. Schumacher
language : en
Publisher: McGraw-Hill/Appleton & Lange
Release Date : 1995
Therapeutic Drug Monitoring written by Gerald E. Schumacher and has been published by McGraw-Hill/Appleton & Lange this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.
Handbook Of Drug Monitoring Methods
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Author : Amitava Dasgupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-23
Handbook Of Drug Monitoring Methods written by Amitava Dasgupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-23 with Medical categories.
Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.
Improving And Accelerating Therapeutic Development For Nervous System Disorders
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2014-02-06
Improving And Accelerating Therapeutic Development For Nervous System Disorders written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-06 with Medical categories.
Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Therapeutic Drug Monitoring Data
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Author : Catherine A. Hammett-Stabler
language : en
Publisher:
Release Date : 2007-01-01
Therapeutic Drug Monitoring Data written by Catherine A. Hammett-Stabler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-01 with Drug monitoring categories.
Clinical Pharmacy Education Practice And Research
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Author : Dixon Thomas
language : en
Publisher: Elsevier
Release Date : 2018-11-23
Clinical Pharmacy Education Practice And Research written by Dixon Thomas and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-23 with Business & Economics categories.
Clinical Pharmacy Education, Practice and Research offers readers a solid foundation in clinical pharmacy and related sciences through contributions by 83 leading experts in the field from 25 countries. This book stresses educational approaches that empower pharmacists with patient care and research competencies. The learning objectives and writing style of the book focus on clarifying the concepts comprehensively for a pharmacist, from regular patient counseling to pharmacogenomics practice. It covers all interesting topics a pharmacist should know. This book serves as a basis to standardize and coordinate learning to practice, explaining basics and using self-learning strategies through online resources or other advanced texts. With an educational approach, it guides pharmacy students and pharmacists to learn quickly and apply. Clinical Pharmacy Education, Practice and Research provides an essential foundation for pharmacy students and pharmacists globally. Covers the core information needed for pharmacy practice courses Includes multiple case studies and practical situations with 70% focused on practical clinical pharmacology knowledge Designed for educational settings, but also useful as a refresher for advanced students and researchers
Handbook Of Analytical Therapeutic Drug Monitoring And Toxicology 1996
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Author : Steven H.Y. Wong
language : en
Publisher: CRC Press
Release Date : 2017-11-22
Handbook Of Analytical Therapeutic Drug Monitoring And Toxicology 1996 written by Steven H.Y. Wong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Medical categories.
Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.