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Combating Antimicrobial Resistance

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Combating Antimicrobial Resistance

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2018-01-08

Combating Antimicrobial Resistance written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-08 with Medical categories.

As of 2017, the emergence and spread of antimicrobial resistance continues unabated around the world, leaving devastating health and economic outcomes in its wake. Those consequences will multiply if collaborative global action is not taken to address the spread of resistance. Major drivers of antimicrobial resistance in humans have been accelerated by inappropriate antimicrobial prescribing in health care practices; the inappropriate use of antimicrobials in livestock; and the promulgation of antibiotic resistance genes in the environment. To explore the issue of antimicrobial resistance, the Forum of Microbial Threats planned a public workshop. Participants explored issues of antimicrobial resistance through the lens of One Health, which is a collaborative approach of multiple disciplines - working locally, nationally, and globally - for strengthening systems to counter infectious diseases and related issues that threaten human, animal, and environmental health, with an end point of improving global health and achieving gains in development. They also discussed immediate and short-term actions and research needs that will have the greatest effect on reducing antimicrobial resistance, while taking into account the complexities of bridging different sectors and disciplines to address this global threat. This publication summarizes the presentations and discussions from the workshop.

Antibiotic Resistant Bacteria A Challenge To Modern Medicine

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Author : Sadhana Sagar
language : en
Publisher: Springer Nature
Release Date : 2019-11-14

Antibiotic Resistant Bacteria A Challenge To Modern Medicine written by Sadhana Sagar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-14 with Medical categories.

This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species. The ability of different species of bacteria to resist the antimicrobial agent has become a global problem. As such, the book provides a comprehensive overview of the advances in our understanding of the origin and mechanism of resistance, discusses the modern concept of the biochemical and genetic basis of antibacterial resistance and highlights the clinical and economic implications of the increased prevalence of antimicrobial resistant pathogens and their ecotoxic effects. It also reviews various strategies to curtail the emergence and examines a number of innovative therapeutic approaches, such as CRISPR, phage therapy, nanoparticles and natural antimicrobials, to combat the spread of resistance.

Antimicrobial Resistance

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Author : World Health Organization
language : en
Publisher:
Release Date : 2014

Antimicrobial Resistance written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.

Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

Mechanisms Of Antibiotic Resistance

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Author : Jun Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2015-06-01

Mechanisms Of Antibiotic Resistance written by Jun Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Antibiotics categories.

Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

New Strategies Combating Bacterial Infection

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Author : Iqbal Ahmad
language : en
Publisher: John Wiley & Sons
Release Date : 2008-11-21

New Strategies Combating Bacterial Infection written by Iqbal Ahmad and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-21 with Science categories.

Combating bacterial infections calls for a multidisciplinary approach and this is what is on offer here. Written by an experienced international team of researchers from various fields ranging from biotechnology to traditional medicine, the book provides complete and comprehensive coverage of topics relevant to new antibacterial drugs. This ready reference and handbook adopts a novel approach, focusing on combating multi-drug resistance in bacteria by developing antibacterials with new target sites, using new advances in drug discovery as well as natural products. Divided into three sections, the first describes the problem of drug resistance and the need for new drugs, while the second treats recent trends and new classes of drugs, including relevant developments in transcriptomics and proteomics leading to new antimicrobial drug discovery, and a new generation of antibiotics and non-antibiotics. The third section on natural products discusses the antibacterial action of phytocompounds, plant extracts, essential oils and honey as well as the role of probiotics in bacterial infections. Invaluable to students of medicine, pharmaceutical sciences, phytomedicine and microbiology and all those wanting to know about the possibilities and limitations of new antibacterial drugs. Furthermore, its coverage of plants and other natural products makes this relevant to the pharmaceutical and herbal industries.

Combating Antimicrobial Resistance

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-12-08

Antibiotic Resistance

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Author : Kateryna Kon
language : en
Publisher: Academic Press
Release Date : 2016-06-24

Antibiotic Resistance written by Kateryna Kon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-24 with Medical categories.

Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance.

Nanotechnology Based Strategies For Combating Antimicrobial Resistance

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Author : Mohmmad Younus Wani
language : en
Publisher: Springer Nature
Release Date : 2024-05-14

Nanotechnology Based Strategies For Combating Antimicrobial Resistance written by Mohmmad Younus Wani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-14 with Medical categories.

This book provides a comprehensive overview of recent advances in nanotechnology as an alternative strategy for addressing antimicrobial resistance (AMR). Examining nanotechnology-based methods such as nanoencapsulation, drug delivery, and conjugation, the text highlights their successful application in treating microbial infections with reduced resistance and off-target toxicity. The introductory section outlines AMR and explores diverse mechanisms of microbial resistance, emphasizing the potential of nanotechnology to surmount these challenges. Subsequent chapters investigate the role of specific nanomaterials—metal nanoparticles, metal oxide nanoparticles, functionalized quantum dots, magnetic nanoparticles, bimetallic nanoparticles, nanocomposites, carbon nanomaterials, and polymer-based nanomaterials—in overcoming antimicrobial resistance. Several chapters focus on the efficacy of nanoemulsions as an antimicrobial delivery method, underscoring their inherent antimicrobial properties, capacity to enhance drug solubility, stability, bioavailability, and targeting potential at the organ and cellular levels. The concluding section provides a detailed review of liposomes, dendrimers-based nanoparticles, and micelles as drug delivery vehicles in the context of combating pathogens resistant to antimicrobials.

Combating Antimicrobial Resistance A One Health Approach

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Author : Ghassan M. Matar
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-14

Combating Antimicrobial Resistance A One Health Approach written by Ghassan M. Matar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-14 with categories.

Nordic Co Operation On Combating Antimicrobial Resistance

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Author : Nordic Council of Ministers
language : en
Publisher: Nordic Council of Ministers
Release Date : 2017-04-04

Nordic Co Operation On Combating Antimicrobial Resistance written by Nordic Council of Ministers and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-04 with Technology & Engineering categories.

Whether it is a doctor treating a patient for pneumonia, or a farmer administering antibiotics to pigs in an attempt to keep various diseases at bay, antibiotics are widely used and taken for granted in many sectors nowadays. This has not always been the case, and this will not be the case in the future if the development of antimicrobial resistance (AMR) is not curbed. The escalating and significant increase in the use of antibiotics has led to a global and growing challenge, in the form of antibiotic-resistant bacteria and microbes in many different areas. If the right policy decisions are not made today, the consequences may be grave in the decades to come. As many as one million people may die each year as a result of antibiotic resistance and the number is growing. The latest calculations show that if the current situation is allowed to continue unchecked, it will lead to a humanitarian and economic disaster. Some forecasts predict that by 2050, multi-resistant bacteria and microbes will kill up to 10 million people worldwide each year. The report 12 initiatives, Nordic co-operation on combating antimicrobial resistance, is a white paper adopted by the Nordic Council. It is developed on the basis of hearing “You don’t die from pneumonia, do you...?”, which took place on 6 December 2016 in the Parliament in Copenhagen, at the request of the Danish Presidency of the Nordic Council Presidium and the President of the Council, Henrik Dam Kristensen. Experts from all five Nordic countries and the appropriate academic environments attended. The report describes at strategy with 7 overall objectives that can be implemented through 12 well-founded tangible initiatives. The initiatives can be efficiently implemented through Nordic cooperation. The Nordic Council has declared its support for the initiatives and recommends the Nordic Council of Ministers to prepare and initiate the implementation.

Combating Antimicrobial Resistance

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