New Strategies Combating Bacterial Infection
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New Strategies Combating Bacterial Infection
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Author : Iqbal Ahmad
language : en
Publisher: John Wiley & Sons
Release Date : 2008-11-21
New Strategies Combating Bacterial Infection written by Iqbal Ahmad and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-21 with Science categories.
Combating bacterial infections calls for a multidisciplinary approach and this is what is on offer here. Written by an experienced international team of researchers from various fields ranging from biotechnology to traditional medicine, the book provides complete and comprehensive coverage of topics relevant to new antibacterial drugs. This ready reference and handbook adopts a novel approach, focusing on combating multi-drug resistance in bacteria by developing antibacterials with new target sites, using new advances in drug discovery as well as natural products. Divided into three sections, the first describes the problem of drug resistance and the need for new drugs, while the second treats recent trends and new classes of drugs, including relevant developments in transcriptomics and proteomics leading to new antimicrobial drug discovery, and a new generation of antibiotics and non-antibiotics. The third section on natural products discusses the antibacterial action of phytocompounds, plant extracts, essential oils and honey as well as the role of probiotics in bacterial infections. Invaluable to students of medicine, pharmaceutical sciences, phytomedicine and microbiology and all those wanting to know about the possibilities and limitations of new antibacterial drugs. Furthermore, its coverage of plants and other natural products makes this relevant to the pharmaceutical and herbal industries.
Insights Into New Strategies To Combat Biofilms
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Author : Sujogya Kumar Panda
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-09
Insights Into New Strategies To Combat Biofilms written by Sujogya Kumar Panda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-09 with Science categories.
Treating Infectious Diseases In A Microbial World
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-01-03
Treating Infectious Diseases In A Microbial World written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-03 with Medical categories.
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
National Strategy And Action Plan For Combating Antibiotic Resistant Bacteria
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Author : Anthony Phillips
language : en
Publisher: Nova Science Publishers
Release Date : 2015
National Strategy And Action Plan For Combating Antibiotic Resistant Bacteria written by Anthony Phillips and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Antibiotics categories.
The discovery of antibiotics in the early 20th century fundamentally transformed human and veterinary medicine. Antibiotics now save millions of lives each year in the United States and around the world. The rise of antibiotic-resistant bacterial strains, however, represents a serious threat to public health and the economy. If the effectiveness of antibiotics (drugs that kill or inhibit the growth of bacteria) is lost, we will no longer be able to reliably and rapidly treat bacterial infections, including bacterial pneumonias, foodborne illnesses, and healthcare-associated infections. As more strains of bacteria become resistant to an ever-larger number of antibiotics, our drug choices have become increasingly limited and more expensive and, in some cases, nonexistent. In a world with few effective antibiotics, modern medical advances such as surgery, transplants, and chemotherapy may no longer be viable due to the threat of infection. This book examines the national strategy and plan for combating antibiotic-resistant bacteria.
The Resistance Phenomenon In Microbes And Infectious Disease Vectors
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2003-03-26
The Resistance Phenomenon In Microbes And Infectious Disease Vectors written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-26 with Medical categories.
The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.
Bacterial Biofilms
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Author : Tony Romeo
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-26
Bacterial Biofilms written by Tony Romeo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-26 with Medical categories.
Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.
National Strategy And Action Plan For Combating Antibiotic Resistant Bacteria
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Author : Anthony Phillips
language : en
Publisher:
Release Date : 2015
National Strategy And Action Plan For Combating Antibiotic Resistant Bacteria written by Anthony Phillips and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with HEALTH & FITNESS categories.
New Weapons To Control Bacterial Growth
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Author : Tomas G. Villa
language : en
Publisher: Springer
Release Date : 2016-03-24
New Weapons To Control Bacterial Growth written by Tomas G. Villa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-24 with Science categories.
Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages or purified lysins), the specific control of pathogenic clostridia, the design of new drugs affecting DNA synthesis in bacteria, the use of fecal-matter transplant strategies, the specific control of quorum sensing responses in bacteria, the use of new peptides as antibiotics and new ways to control bacteria that cause cancer, such as Helicobacter pylori cancers.
Beyond Antibiotics
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Author : Michael A. Schmidt, Ph.D.
language : en
Publisher: North Atlantic Books
Release Date : 2009-01-20
Beyond Antibiotics written by Michael A. Schmidt, Ph.D. and has been published by North Atlantic Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-20 with Health & Fitness categories.
At a time when the numbers of emerging infections and antibiotic-resistant bacteria are rising sharply, the supply of new antibiotic drugs has been steadily decreasing. In addition, many health providers have failed to consider that our bodies are cloaked in a blanket of bacteria so pervasive that the bacterial cells outnumber our “human” cells by a factor of ten. In short, we are living in a microbe’s world and cannot ignore the very real potential for untreatable serious infections. In this timely book, Dr. Michael Schmidt proposes we focus on strengthening ourselves by thinking of our bodies as a “human-microbe hybrid.” This requires taking action to raise our defenses, while preserving the integrity of the microbial elements that live on and within us. Drawing on the latest research from several scientific fields, Schmidt presents a strategy of medicine that can be used to build and balance our system of immune defense and repair. He offers a set of general recommendations that can easily be used to tailor programs to individuals seeking to support health maintenance, prevent illness, fight active acute or chronic infections, and foster faster recovery from infections.
Pneumonia Before Antibiotics
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Author : Scott H. Podolsky
language : en
Publisher: JHU Press
Release Date : 2006-05-01
Pneumonia Before Antibiotics written by Scott H. Podolsky and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-01 with Medical categories.
“Uses [pneumonia] as a vehicle for examining the evolution of therapeutics in America between the ‘Golden Age of Microbiology’ and the ‘Age of Antibiotics.’”—Isis Focusing largely on the treatment of pneumonia in first half of the century with type-specific serotherapy, clinician-historian Scott H. Podolsky provides insight into the rise and clinical evaluation of therapeutic “specifics,” the contested domains of private practice and public health, and—as the treatment of pneumonia made the transition from serotherapy to chemotherapy and antibiotics—the tempo and mode of therapeutic change itself. Type-specific serotherapy, founded on the tenets of applied immunology, justified by controlled clinical trials, and grounded in a novel public ethos, was deemed revolutionary when it emerged to replace supportive therapeutics. With the advent of the even more revolutionary sulfa drugs and antibiotics, pneumonia ceased to be a public health concern and became instead an illness treated in individual patients by individual physicians. Podolsky describes the new therapeutics and the scientists and practitioners who developed and debated them. He finds that, rather than representing a barren era in anticipation of some unknown transformation to come, the first decades of the twentieth-century shaped the use of, and reliance upon, the therapeutic specific throughout the century and beyond. This intriguing study will interest historians of medicine and science, policymakers, and clinicians alike. “Podolsky’s scholarship is awesome, and his grasp of the philosophical and sociologic context of the issues considered make this an important work.” —New England Journal of Medicine “This thoroughly documented, carefully written book is a landmark analysis . . . It should be read by everyone who is involved in research and therapeutic development.” —JAMA