Community Series In Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses Volume Ii
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Community Series In Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses Volume Ii
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Author : Alex Tsoi
language : en
Publisher: Frontiers Media SA
Release Date : 2025-01-27
Community Series In Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses Volume Ii written by Alex Tsoi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-27 with Medical categories.
The ability to understand the underlying mechanisms that drive the heterogeneity in inflammatory responses among patients suffering from immune-mediated conditions is critical. The nature of the immune mechanism ranges from the degree of immune cell activation, to the HLA genotypes, and the intensity of responses of target tissues to cytokines. High throughput experiments have generated significant information for us to facilitate the identification of disease-associated components for different complex immune-mediated conditions (e.g. psoriasis, lupus, rheumatoid arthritis, inflammatory bowel diseases), and the advances in biotechnologies and efficiency in computational resources have further promised cost-effective opportunities to simultaneously study the different aspects in the basic and translational domains of these human diseases. The critical questions we face are to provide efficient inference to integrate these datasets, and translate what we have learned from the disease-associated components to understand the heterogeneity (e.g. ethnic, gender, genetic differences) in disease manifestation and prognosis of these immune-mediated conditions. Translating and integrating big data to understand the intrinsic factors that shape the different unique natures of inflammation processes require an efficient and flexible framework to incorporate signatures of different types.
Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses
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Author : Xu-jie Zhou
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-16
Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses written by Xu-jie Zhou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-16 with Medical categories.
Topic Editor Dr. MacLeod is employed by Janssen. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Controversies In Copd
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Author : Antonio Anzueto
language : en
Publisher: European Respiratory Society
Release Date : 2015-09-01
Controversies In Copd written by Antonio Anzueto and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-01 with Medical categories.
COPD is one of the most common diseases worldwide and is projected to be the third leading cause of death by 2020. But that does not mean it is easy to understand or manage. In everyday practice, pulmonologists face areas of controversy in COPD, for which evidence-based medicine is often unavailable. This ERS Monograph considers where the current controversies in COPD lie, discussing areas such as screening, premature birth, asthma–COPD overlap syndrome, treatment, rehabilitation and palliative care. This book will be of great interest to both clinicians and scientists, and aims to stimulate further discussion about this diverse and fascinating disease. "...contains a vast amount of information on the disease, its prevalence, signs and symptoms, diagnositc tests and treatment options. The book's format makes it quick and simple to find out what you need to know, and its size would make it easy to take to work for use in practice [...] invaluable for anyone working with patients with the disease." Emma Vincent, Nursing Standard
The Fourth Industrial Revolution
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Author : Klaus Schwab
language : en
Publisher: Penguin UK
Release Date : 2017-01-03
The Fourth Industrial Revolution written by Klaus Schwab and has been published by Penguin UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-03 with Business & Economics categories.
The founder and executive chairman of the World Economic Forum on how the impending technological revolution will change our lives We are on the brink of the Fourth Industrial Revolution. And this one will be unlike any other in human history. Characterized by new technologies fusing the physical, digital and biological worlds, the Fourth Industrial Revolution will impact all disciplines, economies and industries - and it will do so at an unprecedented rate. World Economic Forum data predicts that by 2025 we will see: commercial use of nanomaterials 200 times stronger than steel and a million times thinner than human hair; the first transplant of a 3D-printed liver; 10% of all cars on US roads being driverless; and much more besides. In The Fourth Industrial Revolution, Schwab outlines the key technologies driving this revolution, discusses the major impacts on governments, businesses, civil society and individuals, and offers bold ideas for what can be done to shape a better future for all.
Precision Public Health
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Author : Tarun Weeramanthri
language : en
Publisher: Frontiers Media SA
Release Date : 2018-06-25
Precision Public Health written by Tarun Weeramanthri and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-25 with categories.
Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.
Precision Medicine For Investigators Practitioners And Providers
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Author : Joel Faintuch
language : en
Publisher: Academic Press
Release Date : 2019-11-16
Precision Medicine For Investigators Practitioners And Providers written by Joel Faintuch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-16 with Science categories.
Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. - Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers - Covers disease groups and ancillary information about techniques, resources and consequences - Follows a structured blueprint, ensuring essential chapters items are not overlooked
Computational Immunology
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Author : Josep Bassaganya-Riera
language : en
Publisher: Academic Press
Release Date : 2015-10-21
Computational Immunology written by Josep Bassaganya-Riera and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-21 with Medical categories.
Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. - Offers case studies with different levels of complexity - Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills - Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting
Deep Learning For Cancer Diagnosis
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Author : Utku Kose
language : en
Publisher: Springer Nature
Release Date : 2020-09-12
Deep Learning For Cancer Diagnosis written by Utku Kose and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-12 with Technology & Engineering categories.
This book explores various applications of deep learning to the diagnosis of cancer,while also outlining the future face of deep learning-assisted cancer diagnostics. As is commonly known, artificial intelligence has paved the way for countless new solutions in the field of medicine. In this context, deep learning is a recent and remarkable sub-field, which can effectively cope with huge amounts of data and deliver more accurate results. As a vital research area, medical diagnosis is among those in which deep learning-oriented solutions are often employed. Accordingly, the objective of this book is to highlight recent advanced applications of deep learning for diagnosing different types of cancer. The target audience includes scientists, experts, MSc and PhD students, postdocs, and anyone interested in the subjects discussed. The book can be used as a reference work to support courses on artificial intelligence, medical and biomedicaleducation.
Human Genetics And Genomics
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Author : Bruce R. Korf
language : en
Publisher: John Wiley & Sons
Release Date : 2012-11-19
Human Genetics And Genomics written by Bruce R. Korf and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-19 with Medical categories.
This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice 'Hot topics' boxes that focus on the latest developments in testing, assessment and treatment 'Ethical issues' boxes to prompt further thought and discussion on the implications of genetic developments 'Sources of information' boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.
Social Isolation And Loneliness In Older Adults
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2020-06-14
Social Isolation And Loneliness In Older Adults written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-14 with Social Science categories.
Social isolation and loneliness are serious yet underappreciated public health risks that affect a significant portion of the older adult population. Approximately one-quarter of community-dwelling Americans aged 65 and older are considered to be socially isolated, and a significant proportion of adults in the United States report feeling lonely. People who are 50 years of age or older are more likely to experience many of the risk factors that can cause or exacerbate social isolation or loneliness, such as living alone, the loss of family or friends, chronic illness, and sensory impairments. Over a life course, social isolation and loneliness may be episodic or chronic, depending upon an individual's circumstances and perceptions. A substantial body of evidence demonstrates that social isolation presents a major risk for premature mortality, comparable to other risk factors such as high blood pressure, smoking, or obesity. As older adults are particularly high-volume and high-frequency users of the health care system, there is an opportunity for health care professionals to identify, prevent, and mitigate the adverse health impacts of social isolation and loneliness in older adults. Social Isolation and Loneliness in Older Adults summarizes the evidence base and explores how social isolation and loneliness affect health and quality of life in adults aged 50 and older, particularly among low income, underserved, and vulnerable populations. This report makes recommendations specifically for clinical settings of health care to identify those who suffer the resultant negative health impacts of social isolation and loneliness and target interventions to improve their social conditions. Social Isolation and Loneliness in Older Adults considers clinical tools and methodologies, better education and training for the health care workforce, and dissemination and implementation that will be important for translating research into practice, especially as the evidence base for effective interventions continues to flourish.