Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses
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Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses
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Author : Xu-jie Zhou
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-16
Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses written by Xu-jie Zhou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-16 with Medical categories.
Topic Editor Dr. MacLeod is employed by Janssen. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Community Series In Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses Volume Ii
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Author : Alex Tsoi
language : en
Publisher: Frontiers Media SA
Release Date : 2025-01-27
Community Series In Towards Precision Medicine For Immune Mediated Disorders Advances In Using Big Data And Artificial Intelligence To Understand Heterogeneity In Inflammatory Responses Volume Ii written by Alex Tsoi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-27 with Medical categories.
The ability to understand the underlying mechanisms that drive the heterogeneity in inflammatory responses among patients suffering from immune-mediated conditions is critical. The nature of the immune mechanism ranges from the degree of immune cell activation, to the HLA genotypes, and the intensity of responses of target tissues to cytokines. High throughput experiments have generated significant information for us to facilitate the identification of disease-associated components for different complex immune-mediated conditions (e.g. psoriasis, lupus, rheumatoid arthritis, inflammatory bowel diseases), and the advances in biotechnologies and efficiency in computational resources have further promised cost-effective opportunities to simultaneously study the different aspects in the basic and translational domains of these human diseases. The critical questions we face are to provide efficient inference to integrate these datasets, and translate what we have learned from the disease-associated components to understand the heterogeneity (e.g. ethnic, gender, genetic differences) in disease manifestation and prognosis of these immune-mediated conditions. Translating and integrating big data to understand the intrinsic factors that shape the different unique natures of inflammation processes require an efficient and flexible framework to incorporate signatures of different types.
Rheumatology E Book
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Author : Marc C. Hochberg
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-07-29
Rheumatology E Book written by Marc C. Hochberg and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-29 with Medical categories.
Covering both the scientific basis of rheumatology and practical, clinical information for rheumatologists and trainees, Rheumatology, 8th Edition, remains a leading text in this fast-changing field. Dr. Marc Hochberg and his team of worldwide editors and authors keep you abreast of recent advances in the field— all in a user-friendly, accessible manner. Fully updated from cover to cover, this two-volume text is designed to meet the needs of all practicing and academic rheumatologists as well as arthritis-related health care professionals and scientists interested in rheumatic and musculoskeletal diseases. - Covers the epidemiology, pathogenesis, clinical manifestations, therapeutic approach, and management of all major as well as rarely encountered rheumatic and musculoskeletal diseases. - Discusses clinical examination, imaging principles, differential diagnosis, established and novel therapies, perioperative evaluation, pain management, basic science, and genetics of rheumatic and musculoskeletal diseases. - Uses a consistent, logical, reader-friendly format with templated chapters, concise text, and large-scale, state-of-the-art illustrations for efficient visual reference. - Contains new chapters covering pre-clinical disease and how to address these patients, common comorbidities in rheumatoid arthritis; emerging therapies for systemic sclerosis; immune mediated complications of checkpoint inhibitors; the epidemiology of COVID-19 and rheumatic and musculoskeletal diseases, emerging treatments for osteoarthritis, and big data analytics. - Provides updates to key topics such as systems biology and its impact on our understanding of the pathogenesis of rheumatic and musculoskeletal diseases, the microbiome in rheumatic musculoskeletal diseases, how to manage chronic pain in the patient with a rheumatic disease, drugs and reproductive health, and emerging therapies for patients with RA, SLE, spondyloarthritis, inflammatory muscle disease, and vasculitis. - Shares the knowledge and expertise of numerous new contributing authors, as well as new co-editor Dr. Désirée van der Heijde, who is an expert in psoriatic arthritis, spondyloarthritis, imaging, and clinical epidemiology. - Provides access to concise videos depicting the use of ultrasound for diagnosis and treatment. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. If you encounter issues with your eBook please contact Elsevier eBook+ support via [email protected].
Controversies In Copd
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Author : Antonio Anzueto
language : en
Publisher: European Respiratory Society
Release Date : 2015-09-01
Controversies In Copd written by Antonio Anzueto and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-01 with Medical categories.
COPD is one of the most common diseases worldwide and is projected to be the third leading cause of death by 2020. But that does not mean it is easy to understand or manage. In everyday practice, pulmonologists face areas of controversy in COPD, for which evidence-based medicine is often unavailable. This ERS Monograph considers where the current controversies in COPD lie, discussing areas such as screening, premature birth, asthma–COPD overlap syndrome, treatment, rehabilitation and palliative care. This book will be of great interest to both clinicians and scientists, and aims to stimulate further discussion about this diverse and fascinating disease. "...contains a vast amount of information on the disease, its prevalence, signs and symptoms, diagnositc tests and treatment options. The book's format makes it quick and simple to find out what you need to know, and its size would make it easy to take to work for use in practice [...] invaluable for anyone working with patients with the disease." Emma Vincent, Nursing Standard
Early Rheumatoid Arthritis
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Author : Paul Emery
language : en
Publisher:
Release Date : 2005
Early Rheumatoid Arthritis written by Paul Emery and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Rheumatoid arthritis categories.
This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.
The Fourth Industrial Revolution
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Author : Klaus Schwab
language : en
Publisher: Penguin UK
Release Date : 2017-01-03
The Fourth Industrial Revolution written by Klaus Schwab and has been published by Penguin UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-03 with Business & Economics categories.
The founder and executive chairman of the World Economic Forum on how the impending technological revolution will change our lives We are on the brink of the Fourth Industrial Revolution. And this one will be unlike any other in human history. Characterized by new technologies fusing the physical, digital and biological worlds, the Fourth Industrial Revolution will impact all disciplines, economies and industries - and it will do so at an unprecedented rate. World Economic Forum data predicts that by 2025 we will see: commercial use of nanomaterials 200 times stronger than steel and a million times thinner than human hair; the first transplant of a 3D-printed liver; 10% of all cars on US roads being driverless; and much more besides. In The Fourth Industrial Revolution, Schwab outlines the key technologies driving this revolution, discusses the major impacts on governments, businesses, civil society and individuals, and offers bold ideas for what can be done to shape a better future for all.
Precision Public Health
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Author : Tarun Weeramanthri
language : en
Publisher: Frontiers Media SA
Release Date : 2018-06-25
Precision Public Health written by Tarun Weeramanthri and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-25 with categories.
Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.
Critical Issues In Head And Neck Oncology
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Author : Jan B. Vermorken
language : en
Publisher: Springer Nature
Release Date : 2023-03-27
Critical Issues In Head And Neck Oncology written by Jan B. Vermorken and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-27 with Medical categories.
This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.
Artificial Intelligence In Oncology Drug Discovery And Development
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Author : John W. Cassidy
language : en
Publisher:
Release Date : 2020
Artificial Intelligence In Oncology Drug Discovery And Development written by John W. Cassidy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Antineoplastic agents categories.
Computational Immunology
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Author : Josep Bassaganya-Riera
language : en
Publisher: Academic Press
Release Date : 2015-10-21
Computational Immunology written by Josep Bassaganya-Riera and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-21 with Medical categories.
Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. - Offers case studies with different levels of complexity - Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills - Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting